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edrophonium and Kidney Failure, Chronic

edrophonium has been researched along with Kidney Failure, Chronic in 2 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
" When present, the physician may want to determine whether the patient has myasthenia gravis--the commonest of all neuromuscular disorders--and administer the edrophonium (Tensilon) test."3.69Interpretation of positive edrophonium (Tensilon) test in patients with end-stage renal disease. ( Bank, N; Khan, GA, 1995)
"Seventeen patients with end stage chronic renal failure and 18 patients with normal renal function were anaesthetized with 0."2.67Neuromuscular block with doxacurium (BW A938U) in patients with normal or absent renal function. ( Cashman, JN; Jones, RM; Luke, JJ, 1990)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khan, GA1
Bank, N1
Cashman, JN1
Luke, JJ1
Jones, RM1

Trials

1 trial available for edrophonium and Kidney Failure, Chronic

ArticleYear
Neuromuscular block with doxacurium (BW A938U) in patients with normal or absent renal function.
    British journal of anaesthesia, 1990, Volume: 64, Issue:2

    Topics: Adult; Aged; Anesthesia, General; Drug Evaluation; Edrophonium; Female; Hemodynamics; Humans; Isoqui

1990

Other Studies

1 other study available for edrophonium and Kidney Failure, Chronic

ArticleYear
Interpretation of positive edrophonium (Tensilon) test in patients with end-stage renal disease.
    Renal failure, 1995, Volume: 17, Issue:1

    Topics: Aged; Chronic Disease; Diabetic Nephropathies; Edrophonium; False Positive Reactions; Female; Humans

1995