edrophonium has been researched along with Fatigue in 10 studies
Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When myasthenia gravis is suspected, the presence of sustained gaze fatigue provides a tentative clinical diagnosis to be confirmed by pharmacologic testing." | 1.26 | Myasthenic sustained gaze fatigue. ( Glaser, JS; Osher, RH, 1980) |
| "In two subjects with paramyotonia congenita the isometric torque generated by the abductor digiti minimi and the surface EMG recorded over ADM decreased during prolonged or repetitive contractions, whether these were voluntarily or electrically induced." | 1.25 | Contractile properties of the abductor digiti minimi muscle in paramyotonia congenita. ( Burke, D; Lethlean, AK; Skuse, NF, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Osher, RH | 1 |
| Glaser, JS | 1 |
| Trojan, DA | 2 |
| Cashman, NR | 2 |
| Gendron, D | 1 |
| Barton, JJ | 1 |
| Szobor, A | 1 |
| Sellman, MS | 1 |
| Mayer, RF | 1 |
| Patten, BM | 1 |
| Hart, A | 1 |
| Lovelace, R | 1 |
| Lundberg, PO | 1 |
| Stålberg, E | 1 |
| Thiele, B | 1 |
| Burke, D | 1 |
| Skuse, NF | 1 |
| Lethlean, AK | 1 |
| Schwab, RS | 1 |
| Perlo, VP | 1 |
1 review available for edrophonium and Fatigue
| Article | Year |
|---|---|
Quantitative ocular tests for myasthenia gravis: a comparative review with detection theory analysis.
Topics: Edrophonium; Electronystagmography; Eye Movements; Fatigue; Humans; Myasthenia Gravis; Nystagmus, Pa | 1998 |
9 other studies available for edrophonium and Fatigue
| Article | Year |
|---|---|
Myasthenic sustained gaze fatigue.
Topics: Adrenal Cortex Hormones; Blepharoptosis; Diplopia; Edrophonium; Esotropia; Eye Movements; Fatigue; H | 1980 |
Anticholinesterases in post-poliomyelitis syndrome.
Topics: Edrophonium; Electromyography; Fatigue; Humans; Muscle Contraction; Neuromuscular Junction; Postpoli | 1995 |
Anticholinesterase-responsive neuromuscular junction transmission defects in post-poliomyelitis fatigue.
Topics: Adult; Aged; Edrophonium; Electric Stimulation; Electromyography; Fatigue; Humans; Middle Aged; Musc | 1993 |
[Diagnosis and differential diagnosis of myasthenia gravis].
Topics: Adolescent; Adult; Diagnosis, Differential; Edrophonium; Electromyography; Electrooculography; Eye M | 1975 |
Weakness and 'tiredness': when to suspect myasthenia gravis.
Topics: Aged; Antibodies; Diagnosis, Differential; Edrophonium; Electromyography; Fatigue; Female; Humans; M | 1985 |
Multiple sclerosis associated with defects in neuromuscular transmission.
Topics: Adult; Edrophonium; Electric Stimulation; Electromyography; Evoked Potentials; Fatigue; Female; Huma | 1972 |
Paralysis periodica paramyotonica. A clinical and neurophysiological study.
Topics: Acetazolamide; Acetylcholine; Adult; Alanine Transaminase; Aspartate Aminotransferases; Calcium; Cre | 1974 |
Contractile properties of the abductor digiti minimi muscle in paramyotonia congenita.
Topics: Adult; Cold Temperature; Edrophonium; Electric Stimulation; Electromyography; Facial Muscles; Fatigu | 1974 |
Syndromes simulating myasthenia gravis.
Topics: Adult; Aged; Brain Diseases; Brain Stem; Diagnosis, Differential; Edrophonium; Extrapyramidal Tracts | 1966 |