edrophonium has been researched along with Fasciculation in 4 studies
Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
Fasciculation: Involuntary contraction of the muscle fibers innervated by a motor unit. Fasciculations may be visualized as a muscle twitch or dimpling under the skin, but usually do not generate sufficient force to move a limb. They may represent a benign condition or occur as a manifestation of MOTOR NEURON DISEASE or PERIPHERAL NERVOUS SYSTEM DISEASES. (Adams et al., Principles of Neurology, 6th ed, p1294)
Excerpt | Relevance | Reference |
---|---|---|
"In addition, muscles with frequent fasciculations showed a larger decrement than the ones with rare fasciculation." | 1.26 | Amyotrophic lateral sclerosis. Impairment of neuromuscular transmission. ( Denys, EH; Norris, FH, 1979) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (75.00) | 18.7374 |
1990's | 1 (25.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
OSSERMAN, KE | 1 |
KAPLAN, LI | 1 |
Denys, EH | 1 |
Norris, FH | 1 |
Okamoto, M | 1 |
Walewski, JL | 1 |
Artusio, JF | 1 |
Riker, WF | 1 |
Uebayashi, Y | 1 |
Yoshida, S | 1 |
Yase, Y | 1 |
Bessho, H | 1 |
4 other studies available for edrophonium and Fasciculation
Article | Year |
---|---|
Rapid diagnostic test for myasthenia gravis: increased muscle strength, without fasciculations, after intravenous administration of edrophonium (tensilon) chloride.
Topics: Administration, Intravenous; Chlorides; Curare; Diagnostic Tests, Routine; Edrophonium; Fasciculatio | 1952 |
Amyotrophic lateral sclerosis. Impairment of neuromuscular transmission.
Topics: Adolescent; Adult; Aged; Amyotrophic Lateral Sclerosis; Cold Temperature; Edrophonium; Fasciculation | 1979 |
Neuromuscular pharmacology in rat neonates: development of responsiveness to prototypic blocking and reversal drugs.
Topics: 4-Aminopyridine; Aging; Animals; Animals, Newborn; Cholinesterase Inhibitors; Curare; Dose-Response | 1992 |
[Spontaneous discharges in motor neuron disease: evocation by edrophonium and degenerative process].
Topics: Adult; Aged; Edrophonium; Electromyography; Fasciculation; Female; Humans; Male; Middle Aged; Motor | 1987 |