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edrophonium and Esophageal Diseases

edrophonium has been researched along with Esophageal Diseases in 27 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Esophageal Diseases: Pathological processes in the ESOPHAGUS.

Research Excerpts

ExcerptRelevanceReference
"Edrophonium is a widely used provocative agent in the evaluation of noncardiac chest pain, with reported positivity rates of 30-55%."9.07Interaction between patient and test administrator may influence the results of edrophonium provocative testing in patients with noncardiac chest pain. ( Achkar, E; Falk, GW; Fleshler, B; Revta, R; Rose, S, 1993)
"Ten patients with anginal symptoms and ergonovine-induced chest pain without coronary artery spasm had esophageal manometry with provocative pharmacologic testing."7.66Provocation of esophageal pain by ergonovine or edrophonium. ( Cohen, S; Goldberg, S; Hirshfeld, JW; London, RL; Ouyang, A; Snape, WJ, 1981)
"Edrophonium is a widely used provocative agent in the evaluation of noncardiac chest pain, with reported positivity rates of 30-55%."5.07Interaction between patient and test administrator may influence the results of edrophonium provocative testing in patients with noncardiac chest pain. ( Achkar, E; Falk, GW; Fleshler, B; Revta, R; Rose, S, 1993)
"We combined edrophonium provocative testing with the technique of radionuclide oesophageal transit (RET) in 30 consecutive patients with non-cardiac chest pain (NCCP) and 12 controls."3.68The clinical utility of provocative radionuclide oesophageal transit in the evaluation of non-cardiac chest pain. ( Elloway, RS; Jacobs, MP; Mantil, JC; Nathan, MF, 1992)
" In 8 (24%) the pain proved to be related to oesophageal motor disorders unaccompanied by gastro-oesophageal reflux; in 12 (36%) acid reflux contributed to chest pain; but in the remaining 13 (40%) identical chest pain episodes were due to various mechanisms including reflux without motor disorders, motor disorders without reflux, motor disorders without reflux but with positive acid-perfusion test, and acid reflux without motility disorders but with positive edrophonium-stimulation test."3.67The irritable oesophagus--a frequent cause of angina-like pain. ( Ghillebert, G; Janssens, J; Vantrappen, G, 1987)
" The patient's chest discomfort and concomitant esophageal spasm were provoked by intravenous infusion of edrophonium chloride during esophageal manometry."3.67Chest pain associated with mitral valve prolapse. Evidence for esophageal origin. ( Day, FP; Koch, KL; Spears, PF, 1986)
"Ten patients with anginal symptoms and ergonovine-induced chest pain without coronary artery spasm had esophageal manometry with provocative pharmacologic testing."3.66Provocation of esophageal pain by ergonovine or edrophonium. ( Cohen, S; Goldberg, S; Hirshfeld, JW; London, RL; Ouyang, A; Snape, WJ, 1981)
"A 44."1.32Prevalence of esophageal disorders in patients with recurrent chest pain. ( Barroso, MS; Losada, H; Manterola, C; Muñoz, S; Vial, M, 2004)
"Edrophonium continues to be a relatively sensitive test for noncardiac chest pain."1.27Comparison of hypertonic glucose to other provocative tests in patients with noncardiac chest pain. ( Hendrix, EA; Nasrallah, SM, 1987)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199019 (70.37)18.7374
1990's7 (25.93)18.2507
2000's1 (3.70)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Manterola, C1
Barroso, MS1
Losada, H1
Muñoz, S1
Vial, M1
Benjamin, SB1
Richter, JE4
Cordova, CM1
Knuff, TE1
Castell, DO4
London, RL1
Ouyang, A2
Snape, WJ1
Goldberg, S1
Hirshfeld, JW1
Cohen, S3
Anselmino, M1
Clark, GW1
Hinder, RA1
Rose, S1
Achkar, E1
Falk, GW1
Fleshler, B1
Revta, R1
Mellow, M1
Elloway, RS1
Jacobs, MP1
Nathan, MF1
Mantil, JC1
Hewson, EG1
Dalton, CB1
Hackshaw, BT2
Wu, WC2
Humeau, B1
Cloarec, D1
Simon, J1
Bruley des Varannes, S1
Le Bodic, L1
Bouhour, JB1
Galmiche, JP1
Ghillebert, G2
Janssens, J3
Vantrappen, G3
Nevens, F1
Piessens, J1
Limburg, AJ1
Beekhuis, H1
van Dijk, RB1
Kleibeuker, JH1
Soffer, EE1
Scalabrini, P1
Wingate, DL1
Breumelhof, R1
Smout, AJ1
Breedijk, M1
Akkermans, LM1
Nadorp, JH1
De Caestecker, JS1
Pryde, A1
Heading, RC1
Nasrallah, SM1
Hendrix, EA1
Lee, CA1
Reynolds, JC1
Baker, L1
Linsell, J1
Owen, WJ1
Mason, RC1
Anggiansah, A1
Tibbling, L1
Ask, P1
Pope, CE1
Barish, CF1
Bordet, E1
Hecketsweiler, P1
Denis, P1
Spears, PF1
Koch, KL1
Day, FP1
Oshin, DL1
Hollis, JB1
Fisher, R1
Lipshutz, W1
Turner, R1
Myers, A1
Schumacher, R1

Reviews

1 review available for edrophonium and Esophageal Diseases

ArticleYear
Esophageal chest pain: state of the art.
    Surgery annual, 1993, Volume: 25 Pt 1

    Topics: Bethanechol; Bethanechol Compounds; Calcium Channel Blockers; Chest Pain; Diagnosis, Differential; E

1993

Trials

2 trials available for edrophonium and Esophageal Diseases

ArticleYear
Interaction between patient and test administrator may influence the results of edrophonium provocative testing in patients with noncardiac chest pain.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:1

    Topics: Adult; Aged; Chest Pain; Coronary Angiography; Edrophonium; Esophageal Diseases; Female; Humans; Mal

1993
Graded esophageal balloon distention. A new provocative test for noncardiac chest pain.
    Digestive diseases and sciences, 1986, Volume: 31, Issue:12

    Topics: Acids; Adult; Aged; Catheterization; Chest Pain; Diagnosis, Differential; Edrophonium; Esophageal Di

1986

Other Studies

24 other studies available for edrophonium and Esophageal Diseases

ArticleYear
Prevalence of esophageal disorders in patients with recurrent chest pain.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2004, Volume: 17, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Chest Pain; Cross-Sectional Studies; Diagnosis, Differential; Edroph

2004
Prospective manometric evaluation with pharmacologic provocation of patients with suspected esophageal motility dysfunction.
    Gastroenterology, 1983, Volume: 84, Issue:5 Pt 1

    Topics: Adult; Aged; Bethanechol Compounds; Deglutition Disorders; Edrophonium; Esophageal Achalasia; Esopha

1983
Provocation of esophageal pain by ergonovine or edrophonium.
    Gastroenterology, 1981, Volume: 81, Issue:1

    Topics: Adult; Angina Pectoris; Coronary Disease; Diagnosis, Differential; Edrophonium; Ergonovine; Esophage

1981
Symptomatic diffuse esophageal spasm. Manometric follow-up and response to cholinergic stimulation and cholinesterase inhibition.
    Gastroenterology, 1977, Volume: 73, Issue:2

    Topics: Adult; Bethanechol Compounds; Deglutition Disorders; Edrophonium; Esophageal Diseases; Esophagus; Fo

1977
The clinical utility of provocative radionuclide oesophageal transit in the evaluation of non-cardiac chest pain.
    European journal of nuclear medicine, 1992, Volume: 19, Issue:2

    Topics: Chest Pain; Edrophonium; Esophageal Diseases; Esophageal Motility Disorders; Esophagus; Female; Huma

1992
The prevalence of abnormal esophageal test results in patients with cardiovascular disease and unexplained chest pain.
    Archives of internal medicine, 1990, Volume: 150, Issue:5

    Topics: Acids; Adult; Aged; Angioplasty, Balloon; Cardiovascular Diseases; Chest Pain; Coronary Artery Bypas

1990
[Pseudo-angina pain of esophageal origin. Results of functional study and value of the balloon distention test].
    Gastroenterologie clinique et biologique, 1990, Volume: 14, Issue:4

    Topics: Adult; Aged; Angina Pectoris; Chest Pain; Diagnosis, Differential; Edrophonium; Esophageal Diseases;

1990
Ambulatory 24 hour intraoesophageal pH and pressure recordings v provocation tests in the diagnosis of chest pain of oesophageal origin.
    Gut, 1990, Volume: 31, Issue:7

    Topics: Adult; Aged; Ambulatory Care; Chest Pain; Edrophonium; Esophageal Diseases; Esophagus; Female; Human

1990
Noncardiac chest pain: is the esophagus really a frequent source?
    Scandinavian journal of gastroenterology, 1990, Volume: 25, Issue:8

    Topics: Chest Pain; Edrophonium; Esophageal Diseases; Esophagoscopy; Female; Gastroesophageal Reflux; Humans

1990
[Role of manometry in the diagnosis of motor disorders of the esophagus].
    Presse medicale (Paris, France : 1983), 1989, Mar-25, Volume: 18, Issue:12

    Topics: Chest Pain; Deglutition Disorders; Diagnosis, Differential; Edrophonium; Esophageal Diseases; Esopha

1989
Spontaneous noncardiac chest pain: value of ambulatory esophageal pH and motility monitoring.
    Digestive diseases and sciences, 1989, Volume: 34, Issue:11

    Topics: Adult; Aged; Chest Pain; Edrophonium; Esophageal Diseases; Esophageal Motility Disorders; Female; Hu

1989
[The value of ambulatory 24-hour esophageal manometry in the diagnosis of retrosternal pain of non-cardiac origin].
    Nederlands tijdschrift voor geneeskunde, 1989, Oct-28, Volume: 133, Issue:43

    Topics: Chest Pain; Edrophonium; Esophageal Diseases; Esophagus; Female; Humans; Hydrogen-Ion Concentration;

1989
The irritable oesophagus--a frequent cause of angina-like pain.
    Lancet (London, England), 1987, May-30, Volume: 1, Issue:8544

    Topics: Adult; Aged; Angina Pectoris; Diagnosis, Differential; Edrophonium; Esophageal Diseases; Esophagosco

1987
Comparison of intravenous edrophonium and oesophageal acid perfusion during oesophageal manometry in patients with non-cardiac chest pain.
    Gut, 1988, Volume: 29, Issue:8

    Topics: Adolescent; Adult; Aged; Chest Pain; Edrophonium; Esophageal Diseases; Esophagus; Female; Humans; Hy

1988
Comparison of hypertonic glucose to other provocative tests in patients with noncardiac chest pain.
    The American journal of gastroenterology, 1987, Volume: 82, Issue:5

    Topics: Adolescent; Adult; Aged; Chest Pain; Deglutition Disorders; Diagnosis, Differential; Edrophonium; Es

1987
Esophageal chest pain. Value of high-dose provocative testing with edrophonium chloride in patients with normal esophageal manometries.
    Digestive diseases and sciences, 1987, Volume: 32, Issue:7

    Topics: Adult; Aged; Chest Pain; Edrophonium; Esophageal Diseases; Esophagus; Female; Humans; Male; Manometr

1987
Edrophonium provocation test in the diagnosis of diffuse oesophageal spasm.
    The British journal of surgery, 1987, Volume: 74, Issue:8

    Topics: Adolescent; Adult; Aged; Edrophonium; Esophageal Diseases; Evaluation Studies as Topic; Humans; Mano

1987
Electromyography of human oesophageal smooth muscle.
    Scandinavian journal of gastroenterology, 1986, Volume: 21, Issue:5

    Topics: Animals; Atropine; Deglutition; Edrophonium; Electromyography; Esophageal Diseases; Esophagogastric

1986
[Atypical thoracic pain and the edrophonium (Tensilon) test].
    Gastroenterologie clinique et biologique, 1986, Volume: 10, Issue:1

    Topics: Adult; Aged; Edrophonium; Esophageal Diseases; Female; Humans; Male; Middle Aged; Pain; Thorax

1986
Chest pain associated with mitral valve prolapse. Evidence for esophageal origin.
    Archives of internal medicine, 1986, Volume: 146, Issue:4

    Topics: Adult; Edrophonium; Esophageal Diseases; Humans; Male; Manometry; Mitral Valve Prolapse; Pain; Spasm

1986
Edrophonium: a useful provocative test for esophageal chest pain.
    Annals of internal medicine, 1985, Volume: 103, Issue:1

    Topics: Adult; Aged; Coronary Angiography; Coronary Vessels; Edrophonium; Esophageal Diseases; Esophagus; Fe

1985
Edrophonium, ergonovine, and the diagnosis of chest pain.
    Annals of internal medicine, 1985, Volume: 103, Issue:6 ( Pt 1)

    Topics: Coronary Vasospasm; Edrophonium; Ergonovine; Esophageal Diseases; Humans; Pain; Thorax

1985
Esophageal function in elderly man. A new look at "presbyesophagus".
    Annals of internal medicine, 1974, Volume: 80, Issue:3

    Topics: Aged; Aging; Deglutition; Edrophonium; Esophageal Diseases; Esophagus; Gastrointestinal Motility; Hu

1974
The pathogenesis of esophageal dysfunction in scleroderma and Raynaud's disease.
    The Journal of clinical investigation, 1972, Volume: 51, Issue:10

    Topics: Adult; Edrophonium; Esophageal Diseases; Esophagus; Gastrins; Humans; Manometry; Methacholine Compou

1972