Page last updated: 2024-10-26

edrophonium and Envenomation, Snakebite

edrophonium has been researched along with Envenomation, Snakebite in 6 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Research Excerpts

ExcerptRelevanceReference
" The ptosis clinically resembled myasthenia gravis and improved after intravenous edrophonium."3.67Positive response to edrophonium in death adder (Acanthophis antarcticus) envenomation. ( Hudson, BJ, 1988)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Warrell, DA2
Looareesuwan, S1
White, NJ1
Theakston, RD2
Warrell, MJ1
Kosakarn, W1
Reid, HA1
Flachsenberger, W1
Mirtschin, P1
Singh, G1
Pannu, HS1
Chawla, PS1
Malhotra, S1
Hudson, BJ1
Watt, G1
Hayes, CG1
Yambao, ML1
Sangalang, R1
Ranoa, CP1
Alquizalas, E1
Arsura, EL1

Trials

2 trials available for edrophonium and Envenomation, Snakebite

ArticleYear
Neuromuscular transmission failure due to common krait (Bungarus caeruleus) envenomation.
    Muscle & nerve, 1999, Volume: 22, Issue:12

    Topics: Adolescent; Adult; Animals; Antidotes; Antivenins; Bungarus; Child; Edrophonium; Electric Stimulatio

1999
Positive response to edrophonium in patients with neurotoxic envenoming by cobras (Naja naja philippinensis). A placebo-controlled study.
    The New England journal of medicine, 1986, Dec-04, Volume: 315, Issue:23

    Topics: Adolescent; Adult; Clinical Trials as Topic; Deglutition; Double-Blind Method; Edrophonium; Elapid V

1986

Other Studies

4 other studies available for edrophonium and Envenomation, Snakebite

ArticleYear
Severe neurotoxic envenoming by the Malayan krait Bungarus candidus (Linnaeus): response to antivenom and anticholinesterase.
    British medical journal (Clinical research ed.), 1983, Feb-26, Volume: 286, Issue:6366

    Topics: Adolescent; Adult; Antivenins; Bungarotoxins; Child; Cholinesterase Inhibitors; Edrophonium; Female;

1983
Anticholinesterases as antidotes to envenomation of rats by the death adder (Acanthophis antarcticus).
    Toxicon : official journal of the International Society on Toxinology, 1994, Volume: 32, Issue:1

    Topics: Animals; Antivenins; Atropine; Cholinesterase Inhibitors; Drug Evaluation, Preclinical; Edrophonium;

1994
Positive response to edrophonium in death adder (Acanthophis antarcticus) envenomation.
    Australian and New Zealand journal of medicine, 1988, Volume: 18, Issue:6

    Topics: Adult; Diagnosis, Differential; Edrophonium; Humans; Injections, Intravenous; Male; Myasthenia Gravi

1988
Edrophonium for cobra bite.
    The New England journal of medicine, 1987, Jun-18, Volume: 316, Issue:25

    Topics: Edrophonium; Humans; Snake Bites

1987