Page last updated: 2024-10-26

edrophonium and Emesis

edrophonium has been researched along with Emesis in 2 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Research Excerpts

ExcerptRelevanceReference
" In this randomized, double-blind, placebo-controlled study of 113 healthy children who had received mivacurium as part of a standardized anesthetic regimen, we compared the incidence of postoperative complications after spontaneous recovery and after the use of neostigmine-glycopyrrolate or edrophonium-atropine."9.08Effect of antagonism of mivacurium-induced neuromuscular block on postoperative emesis in children. ( McCulloch, DA; Safavi, FZ; Tan, TS; Watcha, MF; White, PF, 1995)
" In this randomized, double-blind, placebo-controlled study of 113 healthy children who had received mivacurium as part of a standardized anesthetic regimen, we compared the incidence of postoperative complications after spontaneous recovery and after the use of neostigmine-glycopyrrolate or edrophonium-atropine."5.08Effect of antagonism of mivacurium-induced neuromuscular block on postoperative emesis in children. ( McCulloch, DA; Safavi, FZ; Tan, TS; Watcha, MF; White, PF, 1995)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Watcha, MF1
Safavi, FZ1
McCulloch, DA1
Tan, TS1
White, PF1
Huang, CH1
Wang, MJ1
Susetio, L1
Cherng, YG1
Shi, JJ1
Chen, YA1
Chiu, WH1

Trials

2 trials available for edrophonium and Emesis

ArticleYear
Effect of antagonism of mivacurium-induced neuromuscular block on postoperative emesis in children.
    Anesthesia and analgesia, 1995, Volume: 80, Issue:4

    Topics: Anesthesia Recovery Period; Atropine; Child; Double-Blind Method; Edrophonium; Glycopyrrolate; Human

1995
Comparison of the combined effects of atropine and neostigmine with atropine and edrophonium on the occurrence of postoperative nausea and vomiting.
    Ma zui xue za zhi = Anaesthesiologica Sinica, 1993, Volume: 31, Issue:2

    Topics: Adult; Atropine; Chi-Square Distribution; Double-Blind Method; Drug Therapy, Combination; Edrophoniu

1993