edrophonium has been researched along with Eaton-Lambert Myasthenic Syndrome in 4 studies
Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Uneqivocally positive edrophonium tests, both clinically and electrophysiologically, were observed in a classic case of the Lambert-Eaton myasthenic syndrome." | 7.68 | Edrophonium responsiveness not necessarily diagnostic of myasthenia gravis. ( Cho, HK; Oh, SJ, 1990) |
| "Uneqivocally positive edrophonium tests, both clinically and electrophysiologically, were observed in a classic case of the Lambert-Eaton myasthenic syndrome." | 3.68 | Edrophonium responsiveness not necessarily diagnostic of myasthenia gravis. ( Cho, HK; Oh, SJ, 1990) |
| "The case of a patient with fatigable diplopia and ptosis 3 years after removal of a large-cell lung carcinoma is presented." | 1.31 | Myasthenia gravis with a paraneoplastic marker. ( Leavitt, JA, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meriggioli, MN | 1 |
| Sanders, DB | 1 |
| Gajdos, P | 1 |
| Leavitt, JA | 1 |
| Oh, SJ | 1 |
| Cho, HK | 1 |
2 reviews available for edrophonium and Eaton-Lambert Myasthenic Syndrome
| Article | Year |
|---|---|
Advances in the diagnosis of neuromuscular junction disorders.
Topics: Botulism; Cholinesterase Inhibitors; Edrophonium; Electrodiagnosis; Electromyography; Humans; Immuno | 2005 |
[Myasthenic syndrome. Diagnostic trends].
Topics: Adult; Botulism; Cholinesterase Inhibitors; Diagnosis, Differential; Edrophonium; Electromyography; | 2000 |
2 other studies available for edrophonium and Eaton-Lambert Myasthenic Syndrome
| Article | Year |
|---|---|
Myasthenia gravis with a paraneoplastic marker.
Topics: Autoantibodies; Azathioprine; Biomarkers; Blepharoptosis; Calcium Channels; Carcinoma, Large Cell; D | 2000 |
Edrophonium responsiveness not necessarily diagnostic of myasthenia gravis.
Topics: Edrophonium; Electrophysiology; Female; Humans; Lambert-Eaton Myasthenic Syndrome; Middle Aged; Myas | 1990 |