edrophonium has been researched along with Disease Models, Animal in 9 studies
Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The laryngeal chemoreflex results in apnea, laryngospasm, and cardiovascular changes that can be fatal when a liquid stimulus is placed on the laryngeal mucosa of infant mammals." | 3.68 | Cholinergic agents in the laryngeal chemoreflex model of sudden infant death syndrome. ( Goding, GS; Johnson, K; Rimell, F, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Shelton, GD | 1 |
| Rimell, F | 1 |
| Goding, GS | 1 |
| Johnson, K | 1 |
| Takamori, M | 1 |
| Iwanaga, S | 1 |
| Nastuk, WL | 1 |
| Niemi, WD | 1 |
| Alexander, JT | 1 |
| Chang, HW | 1 |
| Nastuk, MA | 1 |
| Sanders, DB | 1 |
| Schleifer, LS | 1 |
| Eldefrawi, ME | 1 |
| Cobb, EE | 1 |
| Johns, TR | 1 |
| Higgs, RH | 1 |
| Castell, DO | 1 |
| Eastwood, GL | 1 |
| Zuckermann, EC | 1 |
| Glaser, GH | 1 |
9 other studies available for edrophonium and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
'Dropped head sign' in myasthenia gravis.
Topics: Animals; Cholinesterase Inhibitors; Disease Models, Animal; Dogs; Edrophonium; Head; Male; Myastheni | 2004 |
Cholinergic agents in the laryngeal chemoreflex model of sudden infant death syndrome.
Topics: Animals; Animals, Newborn; Apnea; Atropine; Blood Pressure; Chemoreceptor Cells; Disease Models, Ani | 1993 |
Experimental myasthenia due to alpha-bungarotoxin.
Topics: Adult; Animals; Bungarotoxins; Disease Models, Animal; Edrophonium; Evoked Potentials; Female; Human | 1976 |
Myasthenia in frogs immunized against cholinergic-receptor protein.
Topics: Action Potentials; Animals; Anura; Disease Models, Animal; Edrophonium; Immunization; Muscle Hypoton | 1979 |
An immunological induced defect of neuromuscular transmission in rats.
Topics: Animals; Antigens; Disease Models, Animal; Edrophonium; Female; Immunization; Myasthenia Gravis; Neo | 1975 |
Studies on the mechanism of esophagitis-induced lower esophageal sphincter hypotension in cats.
Topics: Animals; Bethanechol Compounds; Cats; Disease Models, Animal; Edrophonium; Esophagitis; Esophagogast | 1976 |
Anticonvulsive action of increased calcium concentration in cerebrospinal fluid.
Topics: Acetylcholine; Animals; Anticonvulsants; Calcium; Cats; Disease Models, Animal; Dose-Response Relati | 1973 |