edrophonium has been researched along with Diplopia in 19 studies
Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
Diplopia: A visual symptom in which a single object is perceived by the visual cortex as two objects rather than one. Disorders associated with this condition include REFRACTIVE ERRORS; STRABISMUS; OCULOMOTOR NERVE DISEASES; TROCHLEAR NERVE DISEASES; ABDUCENS NERVE DISEASES; and diseases of the BRAIN STEM and OCCIPITAL LOBE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In three patients with iatrogenic diplopia, static alignment was abnormal but movement range and saccadic velocities were within normal limits." | 2.69 | Clinical evidence of extraocular muscle fiber-type specificity of botulinum toxin. ( Averbuch-Heller, L; Leigh, RJ; Remler, BF; Stahl, JS, 1998) |
| "Four severely affected patients with dysphagia as their leading symptom were examined." | 1.35 | Fiberoptic endoscopic evaluation of swallowing with simultaneous Tensilon application in diagnosis and therapy of myasthenia gravis. ( Dziewas, R; Oelenberg, S; Ringelstein, EB; Teismann, I; Warnecke, T; Zimmermann, J, 2008) |
| "Reports on association of systemic lupus erythematosus (SLE) and myasthenia gravis are sparse." | 1.31 | [Ocular myasthenic syndrome and systemic lupus erythematosus]. ( Budde, M; Gusek-Schneider, GC; Heckmann, JG; Kraus, B, 2002) |
| "The case of a patient with fatigable diplopia and ptosis 3 years after removal of a large-cell lung carcinoma is presented." | 1.31 | Myasthenia gravis with a paraneoplastic marker. ( Leavitt, JA, 2000) |
| "When myasthenia gravis is suspected, the presence of sustained gaze fatigue provides a tentative clinical diagnosis to be confirmed by pharmacologic testing." | 1.26 | Myasthenic sustained gaze fatigue. ( Glaser, JS; Osher, RH, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (52.63) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benjamin, LA | 1 |
| Chipolombwe, J | 1 |
| Domargard, K | 1 |
| Sennik, DK | 1 |
| Suresh, D | 1 |
| Goodall, E | 1 |
| Lane, RJ | 1 |
| Budde, M | 1 |
| Heckmann, JG | 1 |
| Kraus, B | 1 |
| Gusek-Schneider, GC | 1 |
| MANSON, N | 1 |
| STERN, G | 1 |
| Gamio, S | 1 |
| Garcia-Erro, M | 1 |
| Vaccarezza, MM | 1 |
| Minella, JA | 1 |
| Warnecke, T | 1 |
| Teismann, I | 1 |
| Zimmermann, J | 1 |
| Oelenberg, S | 1 |
| Ringelstein, EB | 1 |
| Dziewas, R | 1 |
| Rush, JA | 1 |
| Shafrin, F | 1 |
| Shaw, JR | 1 |
| Osher, RH | 1 |
| Glaser, JS | 2 |
| Arroyo, HA | 1 |
| Stahl, JS | 1 |
| Averbuch-Heller, L | 1 |
| Remler, BF | 1 |
| Leigh, RJ | 1 |
| Leavitt, JA | 1 |
| Padua, L | 1 |
| Stalberg, E | 1 |
| LoMonaco, M | 1 |
| Evoli, A | 1 |
| Batocchi, A | 1 |
| Tonali, P | 1 |
| Williams, IM | 1 |
| Dickinson, P | 1 |
| Sum, AC | 1 |
| Aita, JF | 1 |
| Snyder, DH | 1 |
| Reichl, W | 1 |
| Adelstein, FE | 1 |
| Kunze, K | 1 |
| Hoyt, WF | 1 |
| Keane, JR | 1 |
| Retzlaff, JA | 1 |
| Kearns, TP | 1 |
| Howard, FM | 1 |
| Cronin, ML | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Transnasal Endoscopic Evaluation of Swallowing: Functional Esophagoscopy Using an Ultrathin Video Endoscope in Neurogenic Dysphagia[NCT01995929] | 62 participants (Actual) | Observational | 2013-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for edrophonium and Diplopia
| Article | Year |
|---|---|
[Myasthenia gravis in childhood and adolescence].
Topics: Blepharoptosis; Child; Child, Preschool; Diplopia; Edrophonium; Electromyography; Female; Humans; Ma | 1996 |
3 trials available for edrophonium and Diplopia
| Article | Year |
|---|---|
Clinical evidence of extraocular muscle fiber-type specificity of botulinum toxin.
Topics: Adult; Aged; Anti-Dyskinesia Agents; Botulinum Toxins; Botulism; Diplopia; Edrophonium; Female; Huma | 1998 |
SFEMG in ocular myasthenia gravis diagnosis.
Topics: Adult; Aged; Autoantibodies; Blepharoptosis; Cholinesterase Inhibitors; Diagnosis, Differential; Dip | 2000 |
Tensilon tonography in the diagnosis of myasthenia gravis.
Topics: Clinical Trials as Topic; Curare; Diplopia; Edrophonium; Female; Humans; Intraocular Pressure; Male; | 1967 |
15 other studies available for edrophonium and Diplopia
| Article | Year |
|---|---|
Case report: A young man with progressive weakness, double vision and breathlessness.
Topics: Adolescent; Cholinesterase Inhibitors; Diplopia; Dyspnea; Edrophonium; Humans; Male; Muscle Weakness | 2011 |
A case of diplopia and arm weakness.
Topics: Aged, 80 and over; Arm; Blepharoptosis; Cholinesterase Inhibitors; Diplopia; Edrophonium; Female; Hu | 2009 |
[Ocular myasthenic syndrome and systemic lupus erythematosus].
Topics: Adult; Diplopia; Edrophonium; Female; Humans; Lupus Erythematosus, Systemic; Myasthenia Gravis; Sens | 2002 |
DEFECTS OF NEAR VISION IN MYASTHENIA GRAVIS.
Topics: Accommodation, Ocular; Cholinesterase Inhibitors; Diagnosis; Diplopia; Drug Therapy; Edrophonium; Ey | 1965 |
Myasthenia gravis in childhood.
Topics: Adult; Age of Onset; Blepharoptosis; Child; Child, Preschool; Cholinesterase Inhibitors; Diagnostic | 2004 |
Fiberoptic endoscopic evaluation of swallowing with simultaneous Tensilon application in diagnosis and therapy of myasthenia gravis.
Topics: Aged, 80 and over; Cholinesterase Inhibitors; Conscious Sedation; Deglutition; Deglutition Disorders | 2008 |
Ocular myasthenia presenting as superior oblique weakness.
Topics: Adult; Blepharoptosis; Diplopia; Edrophonium; Humans; Male; Myasthenia Gravis; Ophthalmoplegia; Stra | 1982 |
Testing for myasthenia.
Topics: Blepharoptosis; Diplopia; Edrophonium; Humans; Myasthenia Gravis; Tonometry, Ocular | 1983 |
Myasthenic sustained gaze fatigue.
Topics: Adrenal Cortex Hormones; Blepharoptosis; Diplopia; Edrophonium; Esotropia; Eye Movements; Fatigue; H | 1980 |
Myasthenia gravis with a paraneoplastic marker.
Topics: Autoantibodies; Azathioprine; Biomarkers; Blepharoptosis; Calcium Channels; Carcinoma, Large Cell; D | 2000 |
Edrophonium test in myasthenia: quantitative oculography.
Topics: Aged; Blepharoptosis; Diagnosis, Differential; Diplopia; Edrophonium; Humans; Infrared Rays; Myasthe | 1986 |
Myasthenia gravis and multiple sclerosis: an unusual combination of diseases.
Topics: Adult; Brain; Demyelinating Diseases; Diplopia; Edrophonium; Electroencephalography; Female; gamma-G | 1974 |
[Comparative studies on ocular myasthenia using electromyography, measurement of movement distance and dynamic determination of diplopia].
Topics: Adult; Diplopia; Edrophonium; Electromyography; Eye Movements; Female; Humans; Male; Methods; Myasth | 1969 |
Superior oblique myokymia. Report and discussion on five cases of benign intermittent uniocular microtremor.
Topics: Adult; Brain Stem; Diplopia; Edrophonium; Electromyography; Eye Movements; Female; Humans; Male; Mid | 1970 |
Lancaster red-green test in evaluation of edrophonium effect in myasthenia gravis.
Topics: Adult; Aged; Blepharoptosis; Curare; Diplopia; Edrophonium; Female; Humans; Male; Methods; Myastheni | 1969 |