Page last updated: 2024-10-26

edrophonium and Delayed Awakening from Anesthesia

edrophonium has been researched along with Delayed Awakening from Anesthesia in 2 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Research Excerpts

ExcerptRelevanceReference
"Acetylcholinesterase inhibitors (neostigmine, edrophonium) and encapsulating agents (sugammadex and calabadion) can be used to reverse residual neuromuscular blockade (NMB)."4.93Reversing neuromuscular blockade: inhibitors of the acetylcholinesterase versus the encapsulating agents sugammadex and calabadion. ( Eikermann, M; Haerter, F, 2016)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jones, RS1
Auer, U1
Mosing, M1
Haerter, F1
Eikermann, M1

Reviews

2 reviews available for edrophonium and Delayed Awakening from Anesthesia

ArticleYear
Reversal of neuromuscular block in companion animals.
    Veterinary anaesthesia and analgesia, 2015, Volume: 42, Issue:5

    Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Antidotes; Cholinesterase Inhibitors; De

2015
Reversing neuromuscular blockade: inhibitors of the acetylcholinesterase versus the encapsulating agents sugammadex and calabadion.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:6

    Topics: Anesthesia Recovery Period; Anesthesia, General; Cholinesterase Inhibitors; Delayed Emergence from A

2016