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edrophonium and Coronary Disease

edrophonium has been researched along with Coronary Disease in 9 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
"Ten patients with anginal symptoms and ergonovine-induced chest pain without coronary artery spasm had esophageal manometry with provocative pharmacologic testing."7.66Provocation of esophageal pain by ergonovine or edrophonium. ( Cohen, S; Goldberg, S; Hirshfeld, JW; London, RL; Ouyang, A; Snape, WJ, 1981)
"Ten patients with anginal symptoms and ergonovine-induced chest pain without coronary artery spasm had esophageal manometry with provocative pharmacologic testing."3.66Provocation of esophageal pain by ergonovine or edrophonium. ( Cohen, S; Goldberg, S; Hirshfeld, JW; London, RL; Ouyang, A; Snape, WJ, 1981)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's5 (55.56)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
London, RL1
Ouyang, A1
Snape, WJ1
Goldberg, S1
Hirshfeld, JW1
Cohen, S1
Hookman, P1
Barkin, JS1
Jaklitsch, MT1
Byrne, JG1
Mery, C1
Kooguchi, K1
Maegawa, Y1
Namba, M1
Yaku, H1
Takahashi, A1
Tanaka, Y1
Rossen, RM1
Krikorian, J1
Hancock, EW1
Meesmann, M1
Karagueuzian, HS1
Ino, T1
McGrath, MF1
Mandel, WJ1
Deschner, WK1
Maher, KA1
Cattau, EL1
Benjamin, SB1
Hewson, EG1
Dalton, CB1
Hackshaw, BT1
Wu, WC1
Richter, JE1
Harrison, LA1
Harrison, LH1
Kent, KM1
Epstein, SE1

Trials

1 trial available for edrophonium and Coronary Disease

ArticleYear
[Heart rate reduction using edrophonium during coronary artery bypass grafting without cardiopulmonary bypass].
    Masui. The Japanese journal of anesthesiology, 2000, Volume: 49, Issue:1

    Topics: Aged; Aged, 80 and over; Cardiopulmonary Bypass; Coronary Artery Bypass; Coronary Disease; Edrophoni

2000

Other Studies

8 other studies available for edrophonium and Coronary Disease

ArticleYear
Provocation of esophageal pain by ergonovine or edrophonium.
    Gastroenterology, 1981, Volume: 81, Issue:1

    Topics: Adult; Angina Pectoris; Coronary Disease; Diagnosis, Differential; Edrophonium; Ergonovine; Esophage

1981
The diagnosis and management of unexplained chest pain--is less more?
    The American journal of gastroenterology, 1999, Volume: 94, Issue:8

    Topics: Angina Pectoris; Chest Pain; Coronary Angiography; Coronary Disease; Diagnosis, Differential; Edroph

1999
Thymoma encasing last patent vein graft to the heart.
    The Journal of thoracic and cardiovascular surgery, 1999, Volume: 118, Issue:3

    Topics: Combined Modality Therapy; Coronary Angiography; Coronary Artery Bypass; Coronary Disease; Edrophoni

1999
Ventricular asystole after edrophonium chloride administration.
    JAMA, 1976, Mar-08, Volume: 235, Issue:10

    Topics: Aged; Arrhythmias, Cardiac; Autopsy; Coronary Disease; Edrophonium; Electrocardiography; Female; Hea

1976
The role of enhanced vagal activity on ischemic ventricular tachycardia: pharmacologic basis of inefficiency.
    American heart journal, 1991, Volume: 121, Issue:6 Pt 1

    Topics: Adrenergic beta-Antagonists; Animals; Atropine; Cardiac Pacing, Artificial; Coronary Circulation; Co

1991
Intraesophageal balloon distention versus drug provocation in the evaluation of noncardiac chest pain.
    The American journal of gastroenterology, 1990, Volume: 85, Issue:8

    Topics: Bethanechol; Bethanechol Compounds; Catheterization; Chest Pain; Coronary Disease; Deglutition Disor

1990
The prevalence of abnormal esophageal test results in patients with cardiovascular disease and unexplained chest pain.
    Archives of internal medicine, 1990, Volume: 150, Issue:5

    Topics: Acids; Adult; Aged; Angioplasty, Balloon; Cardiovascular Diseases; Chest Pain; Coronary Artery Bypas

1990
Enhancement of electrical stability of acutely ischemic myocardium by edrophonium.
    Circulation, 1974, Volume: 50, Issue:1

    Topics: Acetylcholine; Animals; Arrhythmias, Cardiac; Atropine; Cholinesterase Inhibitors; Coronary Disease;

1974