edrophonium has been researched along with Convergent Strabismus in 2 studies
Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 70-year-old man with known vascular disease, who had bilateral internuclear ophthalmoplegia, and an 18-month-old girl with a long-term variable esotropia culminating in a postinfectious oculopharyngeal neuropathy both responded with a positive edrophonium chloride (Tensilon) test, strongly suggesting the diagnosis of myasthenia gravis." | 3.66 | Ocular myasthenia gravis mimicking pseudointernuclear ophthalmoplegia and variable esotropia. ( Acers, TE, 1979) |
| "When myasthenia gravis is suspected, the presence of sustained gaze fatigue provides a tentative clinical diagnosis to be confirmed by pharmacologic testing." | 1.26 | Myasthenic sustained gaze fatigue. ( Glaser, JS; Osher, RH, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Osher, RH | 1 |
| Glaser, JS | 1 |
| Acers, TE | 1 |
2 other studies available for edrophonium and Convergent Strabismus
| Article | Year |
|---|---|
Myasthenic sustained gaze fatigue.
Topics: Adrenal Cortex Hormones; Blepharoptosis; Diplopia; Edrophonium; Esotropia; Eye Movements; Fatigue; H | 1980 |
Ocular myasthenia gravis mimicking pseudointernuclear ophthalmoplegia and variable esotropia.
Topics: Aged; Diagnosis, Differential; Edrophonium; Esotropia; Female; Humans; Infant; Male; Myasthenia Grav | 1979 |