edrophonium has been researched along with Bradycardia in 5 studies
Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neostigmine evoked bradycardia in vagotomized, propranolol-treated cats." | 7.68 | Mechanism of the bradycardia produced in the cat by the anticholinesterase neostigmine. ( Bachoo, M; Backman, SB; Polosa, C, 1993) |
| "The dose-response and the doses required to prevent bradycardia in 50% (ED50) and 95% (ED95) of patients were determined for atropine after antagonism of pancuronium-induced neuromuscular blockade in 72 patients with edrophonium-atropine mixtures." | 5.06 | Atropine-edrophonium mixture: a dose-response study. ( Absood, GH; Gomaa, M; Naguib, M, 1988) |
| " Patients with PD+NOH had normal bradycardia responses to edrophonium and normal epinephrine responses to glucagon." | 3.74 | Generalized and neurotransmitter-selective noradrenergic denervation in Parkinson's disease with orthostatic hypotension. ( Goldstein, DS; Holmes, C; Imrich, R; Pechnik, S; Sharabi, Y, 2008) |
| "Neostigmine evoked bradycardia in vagotomized, propranolol-treated cats." | 3.68 | Mechanism of the bradycardia produced in the cat by the anticholinesterase neostigmine. ( Bachoo, M; Backman, SB; Polosa, C, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sharabi, Y | 1 |
| Imrich, R | 1 |
| Holmes, C | 1 |
| Pechnik, S | 1 |
| Goldstein, DS | 1 |
| Chowdhary, S | 1 |
| Marsh, AM | 1 |
| Coote, JH | 1 |
| Townend, JN | 1 |
| Backman, SB | 1 |
| Bachoo, M | 1 |
| Polosa, C | 1 |
| Naguib, M | 1 |
| Gomaa, M | 1 |
| Absood, GH | 1 |
| Suga, F | 1 |
| Snow, JB | 1 |
2 trials available for edrophonium and Bradycardia
| Article | Year |
|---|---|
Nitric oxide and cardiac muscarinic control in humans.
Topics: Adolescent; Adrenergic beta-1 Receptor Agonists; Adrenergic beta-Agonists; Adult; Bradycardia; Cardi | 2004 |
Atropine-edrophonium mixture: a dose-response study.
Topics: Adult; Anesthesia, Inhalation; Atropine; Bradycardia; Dose-Response Relationship, Drug; Drug Combina | 1988 |
3 other studies available for edrophonium and Bradycardia
| Article | Year |
|---|---|
Generalized and neurotransmitter-selective noradrenergic denervation in Parkinson's disease with orthostatic hypotension.
Topics: Aged; Blood Pressure; Bradycardia; Cholinesterase Inhibitors; Edrophonium; Epinephrine; Female; Gluc | 2008 |
Mechanism of the bradycardia produced in the cat by the anticholinesterase neostigmine.
Topics: Acetylcholine; Animals; Bradycardia; Cats; Edrophonium; Heart Rate; Neostigmine; Parasympathetic Ner | 1993 |
Cholinergic control of cochlear blood flow.
Topics: Acetylcholine; Animals; Atropine; Bethanechol Compounds; Blood Pressure; Bradycardia; Cochlea; Edrop | 1969 |