edrophonium has been researched along with Bradyarrhythmia in 5 studies
Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neostigmine evoked bradycardia in vagotomized, propranolol-treated cats." | 7.68 | Mechanism of the bradycardia produced in the cat by the anticholinesterase neostigmine. ( Bachoo, M; Backman, SB; Polosa, C, 1993) |
| "The dose-response and the doses required to prevent bradycardia in 50% (ED50) and 95% (ED95) of patients were determined for atropine after antagonism of pancuronium-induced neuromuscular blockade in 72 patients with edrophonium-atropine mixtures." | 5.06 | Atropine-edrophonium mixture: a dose-response study. ( Absood, GH; Gomaa, M; Naguib, M, 1988) |
| " Patients with PD+NOH had normal bradycardia responses to edrophonium and normal epinephrine responses to glucagon." | 3.74 | Generalized and neurotransmitter-selective noradrenergic denervation in Parkinson's disease with orthostatic hypotension. ( Goldstein, DS; Holmes, C; Imrich, R; Pechnik, S; Sharabi, Y, 2008) |
| "Neostigmine evoked bradycardia in vagotomized, propranolol-treated cats." | 3.68 | Mechanism of the bradycardia produced in the cat by the anticholinesterase neostigmine. ( Bachoo, M; Backman, SB; Polosa, C, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sharabi, Y | 1 |
| Imrich, R | 1 |
| Holmes, C | 1 |
| Pechnik, S | 1 |
| Goldstein, DS | 1 |
| Chowdhary, S | 1 |
| Marsh, AM | 1 |
| Coote, JH | 1 |
| Townend, JN | 1 |
| Backman, SB | 1 |
| Bachoo, M | 1 |
| Polosa, C | 1 |
| Naguib, M | 1 |
| Gomaa, M | 1 |
| Absood, GH | 1 |
| Suga, F | 1 |
| Snow, JB | 1 |
2 trials available for edrophonium and Bradyarrhythmia
| Article | Year |
|---|---|
Nitric oxide and cardiac muscarinic control in humans.
Topics: Adolescent; Adrenergic beta-1 Receptor Agonists; Adrenergic beta-Agonists; Adult; Bradycardia; Cardi | 2004 |
Atropine-edrophonium mixture: a dose-response study.
Topics: Adult; Anesthesia, Inhalation; Atropine; Bradycardia; Dose-Response Relationship, Drug; Drug Combina | 1988 |
3 other studies available for edrophonium and Bradyarrhythmia
| Article | Year |
|---|---|
Generalized and neurotransmitter-selective noradrenergic denervation in Parkinson's disease with orthostatic hypotension.
Topics: Aged; Blood Pressure; Bradycardia; Cholinesterase Inhibitors; Edrophonium; Epinephrine; Female; Gluc | 2008 |
Mechanism of the bradycardia produced in the cat by the anticholinesterase neostigmine.
Topics: Acetylcholine; Animals; Bradycardia; Cats; Edrophonium; Heart Rate; Neostigmine; Parasympathetic Ner | 1993 |
Cholinergic control of cochlear blood flow.
Topics: Acetylcholine; Animals; Atropine; Bethanechol Compounds; Blood Pressure; Bradycardia; Cochlea; Edrop | 1969 |