edrophonium has been researched along with Botulism in 8 studies
Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
Botulism: A disease caused by potent protein NEUROTOXINS produced by CLOSTRIDIUM BOTULINUM which interfere with the presynaptic release of ACETYLCHOLINE at the NEUROMUSCULAR JUNCTION. Clinical features include abdominal pain, vomiting, acute PARALYSIS (including respiratory paralysis), blurred vision, and DIPLOPIA. Botulism may be classified into several subtypes (e.g., food-borne, infant, wound, and others). (From Adams et al., Principles of Neurology, 6th ed, p1208)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Repetitive nerve stimulation (RNS) test confirmed the diagnosis of botulism and edrophonium injection caused a reduction in the decremental response." | 7.69 | Botulism with sensory symptoms diagnosed by neuromuscular transmission studies associated with edrophonium responsiveness. ( Cengiz, B; Kuruoğlu, R; Tokçaer, A, 1996) |
| " Repetitive nerve stimulation (RNS) test confirmed the diagnosis of botulism and edrophonium injection caused a reduction in the decremental response." | 3.69 | Botulism with sensory symptoms diagnosed by neuromuscular transmission studies associated with edrophonium responsiveness. ( Cengiz, B; Kuruoğlu, R; Tokçaer, A, 1996) |
| "In three patients with iatrogenic diplopia, static alignment was abnormal but movement range and saccadic velocities were within normal limits." | 2.69 | Clinical evidence of extraocular muscle fiber-type specificity of botulinum toxin. ( Averbuch-Heller, L; Leigh, RJ; Remler, BF; Stahl, JS, 1998) |
| "The diagnosis of myasthenia gravis is often difficult and calls for a broader use of pharmacological and electrodiagnostic tests." | 1.24 | MYASTHENIA GRAVIS: MEDICAL ASPECTS. ( BUCKLER, WS; ZELDOWICZ, LR, 1965) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ZELDOWICZ, LR | 1 |
| BUCKLER, WS | 1 |
| Meriggioli, MN | 1 |
| Sanders, DB | 1 |
| Edell, TA | 1 |
| Sullivan, CP | 1 |
| Osborn, KM | 1 |
| Gambin, JP | 1 |
| Brenman, RD | 1 |
| Kuruoğlu, R | 1 |
| Cengiz, B | 1 |
| Tokçaer, A | 1 |
| Stahl, JS | 1 |
| Averbuch-Heller, L | 1 |
| Remler, BF | 1 |
| Leigh, RJ | 1 |
| Gajdos, P | 1 |
| Cherington, M | 2 |
| Ryan, DW | 1 |
2 reviews available for edrophonium and Botulism
| Article | Year |
|---|---|
Advances in the diagnosis of neuromuscular junction disorders.
Topics: Botulism; Cholinesterase Inhibitors; Edrophonium; Electrodiagnosis; Electromyography; Humans; Immuno | 2005 |
[Myasthenic syndrome. Diagnostic trends].
Topics: Adult; Botulism; Cholinesterase Inhibitors; Diagnosis, Differential; Edrophonium; Electromyography; | 2000 |
1 trial available for edrophonium and Botulism
| Article | Year |
|---|---|
Clinical evidence of extraocular muscle fiber-type specificity of botulinum toxin.
Topics: Adult; Aged; Anti-Dyskinesia Agents; Botulinum Toxins; Botulism; Diplopia; Edrophonium; Female; Huma | 1998 |
5 other studies available for edrophonium and Botulism
| Article | Year |
|---|---|
MYASTHENIA GRAVIS: MEDICAL ASPECTS.
Topics: Acetylcholine; Botulism; Bromides; Cholinesterase Inhibitors; Decamethonium Compounds; Diagnosis; Di | 1965 |
Wound botulism associated with a positive tensilon test.
Topics: Adult; Botulism; Edrophonium; Humans; Male; Wounds, Penetrating | 1983 |
Botulism with sensory symptoms diagnosed by neuromuscular transmission studies associated with edrophonium responsiveness.
Topics: Adult; Botulism; Edrophonium; Electric Stimulation; Female; Humans; Neural Conduction; Neuromuscular | 1996 |
Botulism. Ten-year experience.
Topics: Adolescent; Adult; Blepharoptosis; Botulinum Antitoxin; Botulism; Colorado; Edrophonium; Electric St | 1974 |
Human type A botulism.
Topics: Acute Disease; Administration, Oral; Adult; Botulism; Edrophonium; Female; Follow-Up Studies; Guanid | 1971 |