edrophonium has been researched along with Batten Turner Congenital Myopathy in 3 studies
Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In two subjects with paramyotonia congenita the isometric torque generated by the abductor digiti minimi and the surface EMG recorded over ADM decreased during prolonged or repetitive contractions, whether these were voluntarily or electrically induced." | 1.25 | Contractile properties of the abductor digiti minimi muscle in paramyotonia congenita. ( Burke, D; Lethlean, AK; Skuse, NF, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lundberg, PO | 1 |
| Stålberg, E | 1 |
| Thiele, B | 1 |
| Burke, D | 1 |
| Skuse, NF | 1 |
| Lethlean, AK | 1 |
| Brown, JC | 1 |
3 other studies available for edrophonium and Batten Turner Congenital Myopathy
| Article | Year |
|---|---|
Paralysis periodica paramyotonica. A clinical and neurophysiological study.
Topics: Acetazolamide; Acetylcholine; Adult; Alanine Transaminase; Aspartate Aminotransferases; Calcium; Cre | 1974 |
Contractile properties of the abductor digiti minimi muscle in paramyotonia congenita.
Topics: Adult; Cold Temperature; Edrophonium; Electric Stimulation; Electromyography; Facial Muscles; Fatigu | 1974 |
Muscle weakness after rest in myotonic disorders; an electrophysiological study.
Topics: Action Potentials; Adult; Edrophonium; Electric Stimulation; Electromyography; Guanidines; Humans; M | 1974 |