Page last updated: 2024-10-26

edrophonium and Atrial Flutter

edrophonium has been researched along with Atrial Flutter in 4 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Atrial Flutter: Rapid, irregular atrial contractions caused by a block of electrical impulse conduction in the right atrium and a reentrant wave front traveling up the inter-atrial septum and down the right atrial free wall or vice versa. Unlike ATRIAL FIBRILLATION which is caused by abnormal impulse generation, typical atrial flutter is caused by abnormal impulse conduction. As in atrial fibrillation, patients with atrial flutter cannot effectively pump blood into the lower chambers of the heart (HEART VENTRICLES).

Research Excerpts

ExcerptRelevanceReference
"Atrial flutter has a fully excitable gap, and procainamide does not convert the gap from full to partial excitability."1.29Pharmacologic alterations in human type I atrial flutter cycle length and monophasic action potential duration. Evidence of a fully excitable gap in the reentrant circuit. ( Ellenbogen, KA; Stambler, BS; Wood, MA, 1996)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stambler, BS2
Wood, MA1
Ellenbogen, KA2
Cummings, P1
Reddy, RC1
Gould, L1
Gomprecht, RF1

Other Studies

4 other studies available for edrophonium and Atrial Flutter

ArticleYear
Pharmacologic alterations in human type I atrial flutter cycle length and monophasic action potential duration. Evidence of a fully excitable gap in the reentrant circuit.
    Journal of the American College of Cardiology, 1996, Volume: 27, Issue:2

    Topics: Action Potentials; Adenosine; Aged; Anti-Arrhythmia Agents; Atrial Flutter; Cardiac Pacing, Artifici

1996
Elucidating the mechanisms of atrial flutter cycle length variability using power spectral analysis techniques.
    Circulation, 1996, Nov-15, Volume: 94, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Atrial Flutter; Edrophonium; Heart; Heart Transplantation;

1996
Supraventricular tachycardias in the emergency room.
    Comprehensive therapy, 1985, Volume: 11, Issue:2

    Topics: Atrial Fibrillation; Atrial Flutter; Digoxin; Edrophonium; Electric Countershock; Emergencies; Human

1985
Use of edrophonium (tensilon) in the evaluation of cardiac arrhythmias.
    American heart journal, 1971, Volume: 82, Issue:6

    Topics: Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Diagnosis, Differentia

1971