Page last updated: 2024-10-26

edrophonium and Arrhythmias, Cardiac

edrophonium has been researched along with Arrhythmias, Cardiac in 15 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.

Research Excerpts

ExcerptRelevanceReference
"However, serious ventricular arrhythmias continued in three patients and appeared in four despite the agent."5.26Clinical evaluation of the enhancement of vagal tone in acute myocardial infarction by edrophonium hydrochloride: effects on ventricular arrhythmias, His bundle electrography, and left ventricular function. ( Amsterdam, EA; DeMaria, AN; Mason, DT; Miller, RR; Olson, HG; Vera, Z, 1977)
"Edrophonium (0."1.26Edrophonium: duration of action and atropine requirement in humans during halothane anesthesia. ( Cronnelly, R; Miller, RD; Morris, RB, 1982)
"However, serious ventricular arrhythmias continued in three patients and appeared in four despite the agent."1.26Clinical evaluation of the enhancement of vagal tone in acute myocardial infarction by edrophonium hydrochloride: effects on ventricular arrhythmias, His bundle electrography, and left ventricular function. ( Amsterdam, EA; DeMaria, AN; Mason, DT; Miller, RR; Olson, HG; Vera, Z, 1977)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199015 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Spitzer, S1
Mason, D1
Lemmon, WM1
Moyer, JH1
Azar, I1
Pham, AN1
Karambelkar, DJ1
Lear, E1
Cronnelly, R1
Morris, RB1
Miller, RD1
Coumel, P1
Krikler, D1
Rosen, MR1
Wellens, HJ1
Zipes, DP1
Rossen, RM1
Krikorian, J1
Hancock, EW1
Gyermek, L2
Miller, RR1
Olson, HG1
Vera, Z1
DeMaria, AN1
Amsterdam, EA1
Mason, DT1
Urquhart, ML1
Ramsey, FM1
Royster, RL1
Morell, RC1
Gerr, P1
Yungbluth, J1
Henry, JD1
McAnallen, K1
Albee, DT1
Mirakhur, RK1
Fletcher, GF1
Torda, TA1
Sinclair, E1
Ulyatt, DB1
Harrison, LA1
Harrison, LH1
Kent, KM1
Epstein, SE1
Reddy, RC1
Gould, L1
Gomprecht, RF1

Trials

2 trials available for edrophonium and Arrhythmias, Cardiac

ArticleYear
Clinical studies on the reversal of the neuromuscular blockade produced by pancuronium bromide. I. The effects of glycopyrrolate and pyridostigmine.
    Current therapeutic research, clinical and experimental, 1975, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atropine; Child; Child, Preschool; Clinical Trials as

1975
Recovery characteristics following antagonism of vecuronium with edrophonium, neostigmine or pyridostigmine.
    AANA journal, 1988, Volume: 56, Issue:2

    Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Cholinesterase Inhibitors; Clinical Trials as Top

1988

Other Studies

13 other studies available for edrophonium and Arrhythmias, Cardiac

ArticleYear
Use of edrophonium (Tensilon) in the evaluation of supraventricular tachycardia.
    The American journal of the medical sciences, 1967, Volume: 254, Issue:4

    Topics: Aged; Arrhythmias, Cardiac; Curare; Diagnosis, Differential; Edrophonium; Electrocardiography; Femal

1967
The heart rate following edrophonium-atropine and edrophonium-glycopyrrolate mixtures.
    Anesthesiology, 1983, Volume: 59, Issue:2

    Topics: Anesthesia, General; Arrhythmias, Cardiac; Atropine; Drug Combinations; Edrophonium; Female; Glycopy

1983
Edrophonium: duration of action and atropine requirement in humans during halothane anesthesia.
    Anesthesiology, 1982, Volume: 57, Issue:4

    Topics: Anesthesia, General; Arrhythmias, Cardiac; Atropine; Blood Pressure; Dose-Response Relationship, Dru

1982
Newer antiarrhythmic drugs.
    Pacing and clinical electrophysiology : PACE, 1978, Volume: 1, Issue:4

    Topics: Administration, Oral; Adult; Amiodarone; Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Ca

1978
Ventricular asystole after edrophonium chloride administration.
    JAMA, 1976, Mar-08, Volume: 235, Issue:10

    Topics: Aged; Arrhythmias, Cardiac; Autopsy; Coronary Disease; Edrophonium; Electrocardiography; Female; Hea

1976
Clinical evaluation of the enhancement of vagal tone in acute myocardial infarction by edrophonium hydrochloride: effects on ventricular arrhythmias, His bundle electrography, and left ventricular function.
    American heart journal, 1977, Volume: 93, Issue:2

    Topics: Acetylcholinesterase; Adult; Aged; Arrhythmias, Cardiac; Bundle of His; Edrophonium; Electrocardiogr

1977
Clinical pharmacology of the reversal of neuromuscular block.
    International journal of clinical pharmacology and biopharmacy, 1977, Volume: 15, Issue:8

    Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atropine; Child; Child, Preschool; Edrophonium; Femal

1977
Heart rate and rhythm following an edrophonium/atropine mixture for antagonism of neuromuscular blockade during fentanyl/N2O/O2 or isoflurane/N2O/O2 anesthesia.
    Anesthesiology, 1987, Volume: 67, Issue:4

    Topics: Adult; Arrhythmias, Cardiac; Atropine; Drug Combinations; Edrophonium; Female; Fentanyl; Heart Rate;

1987
Antagonism of the muscarinic effects of edrophonium with atropine or glycopyrrolate. A comparative study.
    British journal of anaesthesia, 1985, Volume: 57, Issue:12

    Topics: Adult; Arrhythmias, Cardiac; Atropine; Edrophonium; Female; Glycopyrrolate; Heart Rate; Humans; Intr

1985
The effectiveness of edrophonium in 12 patients with supraventricular tachyarrhythmias.
    Medical times, 1971, Volume: 99, Issue:5

    Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Child; Child, Preschool; Edrophonium; Electrocardiogr

1971
Puffer fish (tetrodotoxin) poisoning: clinical record and suggested management.
    The Medical journal of Australia, 1973, 03-24, Volume: 1, Issue:12

    Topics: Adolescent; Animals; Arrhythmias, Cardiac; Consciousness; Edrophonium; Fishes, Poisonous; Foodborne

1973
Enhancement of electrical stability of acutely ischemic myocardium by edrophonium.
    Circulation, 1974, Volume: 50, Issue:1

    Topics: Acetylcholine; Animals; Arrhythmias, Cardiac; Atropine; Cholinesterase Inhibitors; Coronary Disease;

1974
Use of edrophonium (tensilon) in the evaluation of cardiac arrhythmias.
    American heart journal, 1971, Volume: 82, Issue:6

    Topics: Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Diagnosis, Differentia

1971