Page last updated: 2024-10-26

edrophonium and Apnea

edrophonium has been researched along with Apnea in 5 studies

Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

Apnea: A transient absence of spontaneous respiration.

Research Excerpts

ExcerptRelevanceReference
"The laryngeal chemoreflex results in apnea, laryngospasm, and cardiovascular changes that can be fatal when a liquid stimulus is placed on the laryngeal mucosa of infant mammals."3.68Cholinergic agents in the laryngeal chemoreflex model of sudden infant death syndrome. ( Goding, GS; Johnson, K; Rimell, F, 1993)
" The condition is characterized by (1) absence of myasthenia in the mother, (2) occurrence of a similar disorder among siblings, (3) respiratory depression at birth, (4) episodic weakness and apnea during the first two years of life, and (5) improvement with age."3.66Familial infantile myasthenia. ( Chun, RW; Kornguth, SE; Robertson, WC, 1980)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BLAUGRUND, SM1
ROSIN, HD1
GENKINS, G1
OSSERMAN, KE1
Robertson, WC1
Chun, RW1
Kornguth, SE1
Smith, DC1
Ridley, SA1
Donaldson, KF1
Rimell, F1
Goding, GS1
Johnson, K1
Chagnac, Y1
Hadani, M1
Goldhammer, Y1

Other Studies

5 other studies available for edrophonium and Apnea

ArticleYear
STUDIES IN MYASTHENIA GRAVIS: THE ROLE OF TRACHEOTOMY AND CONTROLLED VENTILATION.
    The Annals of otology, rhinology, and laryngology, 1964, Volume: 73

    Topics: Acidosis; Adolescent; Apnea; Autonomic Nervous System Diseases; Carbon Dioxide; Child; Cholinesteras

1964
Familial infantile myasthenia.
    Archives of neurology, 1980, Volume: 37, Issue:2

    Topics: Adolescent; Apnea; Child; Child, Preschool; Edrophonium; Follow-Up Studies; Humans; Infant; Male; My

1980
Fresh frozen plasma and edrophonium in a patient with a plasma cholinesterase deficiency.
    Anaesthesia, 1993, Volume: 48, Issue:6

    Topics: Adult; Apnea; Cholinesterases; Edrophonium; Female; Humans; Monitoring, Physiologic; Neuromuscular J

1993
Cholinergic agents in the laryngeal chemoreflex model of sudden infant death syndrome.
    The Laryngoscope, 1993, Volume: 103, Issue:6

    Topics: Animals; Animals, Newborn; Apnea; Atropine; Blood Pressure; Chemoreceptor Cells; Disease Models, Ani

1993
Myasthenic crisis after intravenous administration of iodinated contrast agent.
    Neurology, 1985, Volume: 35, Issue:8

    Topics: Aged; Apnea; Contrast Media; Diatrizoate; Diatrizoate Meglumine; Edrophonium; Female; Humans; Middle

1985