edrophonium has been researched along with Amyotonia Congenita in 15 studies
Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The value of electronystagmography (ENG) and of tonography in monitoring the beneficial effect of edrophonium chloride (Tensilon) on the extraocular muscles in myasthenia gravis has been assessed." | 3.65 | Ocular myasthenia: evaluation of Tensilon tonography and electronystagmography as diagnostic tests. ( Campbell, MJ; Crombie, AL; Simpson, E; Walton, JN, 1970) |
| "Benzoquinonium (Mytolon) has been shown to produce a curare-like rather than a decamethonium-like paralysis of neuromuscular transmission in the tibialis anterior and soleus muscle of cats and the gastrocnemius muscle of hens." | 3.63 | The neuromuscular blocking action of benzoquinonium chloride in the cat and in the hen. ( BOWMAN, WC, 1958) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (93.33) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HOUGS, W | 1 |
| JOHANSEN, SH | 1 |
| BOWMAN, WC | 1 |
| Dell'Osso, LF | 1 |
| Ayyar, DR | 1 |
| Daroff, RB | 1 |
| Abel, LA | 1 |
| Trojaborg, W | 1 |
| Flagstad, A | 1 |
| Singh, G | 1 |
| Pannu, HS | 1 |
| Chawla, PS | 1 |
| Malhotra, S | 1 |
| Sanders, DB | 1 |
| Schleifer, LS | 1 |
| Eldefrawi, ME | 1 |
| Cobb, EE | 1 |
| Johns, TR | 1 |
| Szobor, A | 1 |
| Uebayashi, Y | 2 |
| Yoshida, S | 2 |
| Yase, Y | 2 |
| Bessho, H | 2 |
| Campbell, MJ | 1 |
| Simpson, E | 1 |
| Crombie, AL | 1 |
| Walton, JN | 1 |
| Wray, SH | 1 |
| Pavan-Langston, D | 1 |
| Stålberg, E | 1 |
| Thiele, B | 1 |
| Jusić, A | 1 |
| Rowland, LP | 1 |
| Lisak, RP | 1 |
| Schotland, DL | 1 |
| DeJesus, PV | 1 |
| Berg, P | 1 |
1 trial available for edrophonium and Amyotonia Congenita
| Article | Year |
|---|---|
Neuromuscular transmission failure due to common krait (Bungarus caeruleus) envenomation.
Topics: Adolescent; Adult; Animals; Antidotes; Antivenins; Bungarus; Child; Edrophonium; Electric Stimulatio | 1999 |
14 other studies available for edrophonium and Amyotonia Congenita
| Article | Year |
|---|---|
Effects of edrophonium and neostigmine on neuromuscular block in the cat.
Topics: Animals; Cats; Edrophonium; Felis; Muscle Relaxants, Central; Neostigmine; Neuromuscular Blockade; N | 1958 |
The neuromuscular blocking action of benzoquinonium chloride in the cat and in the hen.
Topics: Acetylcholine; Animals; Cats; Chickens; Cholinesterase Inhibitors; Cholinesterases; Edrophonium; Fem | 1958 |
Edrophonium test in Eaton-Lambert syndrome: quantitative oculography.
Topics: Aged; Edrophonium; Eye Movements; Female; Fixation, Ocular; Humans; Male; Middle Aged; Myasthenia Gr | 1983 |
A hereditary neuromuscular disorder in dogs.
Topics: Animals; Dog Diseases; Dogs; Edrophonium; Electrophysiology; Evoked Potentials; Female; Guanidine; G | 1982 |
An immunological induced defect of neuromuscular transmission in rats.
Topics: Animals; Antigens; Disease Models, Animal; Edrophonium; Female; Immunization; Myasthenia Gravis; Neo | 1975 |
[Diagnosis and differential diagnosis of myasthenia gravis].
Topics: Adolescent; Adult; Diagnosis, Differential; Edrophonium; Electromyography; Electrooculography; Eye M | 1975 |
[Spontaneous discharges in motor neuron disease: evocation by edrophonium and degenerative process].
Topics: Adult; Aged; Edrophonium; Electromyography; Fasciculation; Female; Humans; Male; Middle Aged; Motor | 1987 |
[An observation of spontaneous discharges by surface EMG in motor neuron disease. Correlation between ratio of evocation by edrophonium and clinical course].
Topics: Adult; Aged; Edrophonium; Electromyography; Female; Humans; Male; Middle Aged; Motor Neurons; Neurom | 1985 |
Ocular myasthenia: evaluation of Tensilon tonography and electronystagmography as diagnostic tests.
Topics: Adolescent; Adult; Aged; Child; Edrophonium; Electrooculography; Eye Manifestations; Female; Humans; | 1970 |
A reevaluation of edrophonium chloride (Tensilon) tonography in the diagnosis of myasthenia gravis. With observations on some other defects of neuromuscular transmission.
Topics: Adolescent; Adult; Aged; Bronchial Neoplasms; Child; Edrophonium; Electromyography; Female; Humans; | 1971 |
Transmission block in terminal nerve twigs: a single fibre electromyographic finding in man.
Topics: Action Potentials; Amyotrophic Lateral Sclerosis; Edrophonium; Electromyography; Humans; Motor Neuro | 1972 |
[Myasthenia gravis, its pathogenetic and electrophysiological differential diagnosis].
Topics: Animals; Antibodies, Antinuclear; Autoimmune Diseases; Decamethonium Compounds; Diagnosis, Different | 1974 |
Myasthenic myopathy and thymoma.
Topics: Edrophonium; Humans; Male; Middle Aged; Muscles; Myasthenia Gravis; Neostigmine; Neuromuscular Disea | 1973 |
Letter: Hypercalcemia and neuromuscular disease.
Topics: Adult; Calcitonin; Carcinoma; Edrophonium; Female; Humans; Hypercalcemia; Middle Aged; Neuromuscular | 1974 |