edrophonium has been researched along with Acute Confusional Senile Dementia in 4 studies
Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neuropathologic data from patients with Alzheimer's disease indicate the presence of neurofibrillary tangles in hypothalamic regions associated with regulation of pituitary hormone release." | 1.27 | Growth hormone response to edrophonium in Alzheimer's disease. ( Bienenfeld, D; Bosmann, HB; Hartford, JT; Thienhaus, OJ; Zemlan, FP, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rakonczay, Z | 1 |
| Ogane, N | 1 |
| Giacobini, E | 1 |
| Struble, R | 1 |
| Thienhaus, OJ | 1 |
| Zemlan, FP | 1 |
| Bienenfeld, D | 1 |
| Hartford, JT | 1 |
| Bosmann, HB | 1 |
| Davidson, M | 1 |
| Davis, BM | 1 |
| Bastiaens, L | 1 |
| Macaluso, J | 1 |
| Aryan, M | 1 |
| Ryan, T | 1 |
| Davis, KL | 1 |
4 other studies available for edrophonium and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Potencies and selectivities of inhibitors of acetylcholinesterase and its molecular forms in normal and Alzheimer's disease brain.
Topics: Acetylcholinesterase; Alzheimer Disease; Benzazepines; Brain; Butyrylcholinesterase; Carbamates; Cer | 2003 |
Differential inhibition of acetylcholinesterase molecular forms in normal and Alzheimer disease brain.
Topics: Acetylcholinesterase; Aged; Alzheimer Disease; Brain; Centrifugation, Density Gradient; Cholinestera | 1992 |
Growth hormone response to edrophonium in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Edrophonium; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Hypo | 1987 |
Growth hormone response to edrophonium in patients with Alzheimer's disease and normal control subjects.
Topics: Aged; Alzheimer Disease; Edrophonium; Female; Growth Hormone; Humans; Male; Middle Aged | 1988 |