edrophonium has been researched along with Achalasia in 6 studies
Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Edrophonium continues to be a relatively sensitive test for noncardiac chest pain." | 1.27 | Comparison of hypertonic glucose to other provocative tests in patients with noncardiac chest pain. ( Hendrix, EA; Nasrallah, SM, 1987) |
| "In idiopathic achalasia, LES relaxation is abnormal because the inhibitory nerves to the sphincter are either absent or functionally impaired." | 1.27 | Integrity of cholinergic innervation to the lower esophageal sphincter in achalasia. ( Arndorfer, RC; Dent, J; Dodds, WJ; Helm, JF; Hogan, WJ; Holloway, RH, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fass, R | 1 |
| Benjamin, SB | 1 |
| Richter, JE | 1 |
| Cordova, CM | 1 |
| Knuff, TE | 1 |
| Castell, DO | 1 |
| Anselmino, M | 1 |
| Clark, GW | 1 |
| Hinder, RA | 1 |
| Nasrallah, SM | 1 |
| Hendrix, EA | 1 |
| Holloway, RH | 1 |
| Dodds, WJ | 1 |
| Helm, JF | 1 |
| Hogan, WJ | 1 |
| Dent, J | 1 |
| Arndorfer, RC | 1 |
| Cohen, S | 1 |
| Fisher, R | 1 |
| Tuch, A | 1 |
2 reviews available for edrophonium and Achalasia
| Article | Year |
|---|---|
Evaluation and diagnosis of noncardiac chest pain.
Topics: Chest Pain; Cholinesterase Inhibitors; Edrophonium; Endoscopy, Gastrointestinal; Ergonovine; Esophag | 2008 |
Esophageal chest pain: state of the art.
Topics: Bethanechol; Bethanechol Compounds; Calcium Channel Blockers; Chest Pain; Diagnosis, Differential; E | 1993 |
4 other studies available for edrophonium and Achalasia
| Article | Year |
|---|---|
Prospective manometric evaluation with pharmacologic provocation of patients with suspected esophageal motility dysfunction.
Topics: Adult; Aged; Bethanechol Compounds; Deglutition Disorders; Edrophonium; Esophageal Achalasia; Esopha | 1983 |
Comparison of hypertonic glucose to other provocative tests in patients with noncardiac chest pain.
Topics: Adolescent; Adult; Aged; Chest Pain; Deglutition Disorders; Diagnosis, Differential; Edrophonium; Es | 1987 |
Integrity of cholinergic innervation to the lower esophageal sphincter in achalasia.
Topics: Adult; Cholinergic Fibers; Edrophonium; Esophageal Achalasia; Esophagogastric Junction; Humans; Mano | 1986 |
The site of denervation in achalasia.
Topics: Acetylcholine; Adolescent; Adult; Aged; Edrophonium; Esophageal Achalasia; Esophagogastric Junction; | 1972 |