edrophonium has been researched along with ALS - Amyotrophic Lateral Sclerosis in 5 studies
Edrophonium: A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
edrophonium : A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In addition, muscles with frequent fasciculations showed a larger decrement than the ones with rare fasciculation." | 1.26 | Amyotrophic lateral sclerosis. Impairment of neuromuscular transmission. ( Denys, EH; Norris, FH, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Killian, JM | 1 |
| Wilfong, AA | 1 |
| Burnett, L | 1 |
| Appel, SH | 1 |
| Boland, D | 1 |
| Denys, EH | 1 |
| Norris, FH | 1 |
| Pascuzzi, RM | 1 |
| Stålberg, E | 1 |
| Thiele, B | 1 |
| Ideta, T | 1 |
| Okamoto, S | 1 |
| Okajima, T | 1 |
| Tokuomi, H | 1 |
5 other studies available for edrophonium and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Decremental motor responses to repetitive nerve stimulation in ALS.
Topics: Action Potentials; Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Edrophonium; Elect | 1994 |
Amyotrophic lateral sclerosis. Impairment of neuromuscular transmission.
Topics: Adolescent; Adult; Aged; Amyotrophic Lateral Sclerosis; Cold Temperature; Edrophonium; Fasciculation | 1979 |
Amyotrophic lateral sclerosis.
Topics: Adult; Aged; Amitriptyline; Amyotrophic Lateral Sclerosis; Cholinesterase Inhibitors; Diagnosis, Dif | 1988 |
Transmission block in terminal nerve twigs: a single fibre electromyographic finding in man.
Topics: Action Potentials; Amyotrophic Lateral Sclerosis; Edrophonium; Electromyography; Humans; Motor Neuro | 1972 |
[Case of myasthenic syndrome with amyotrophic lateral sclerosis].
Topics: Amyotrophic Lateral Sclerosis; Edrophonium; Electromyography; Female; Humans; Middle Aged; Myastheni | 1973 |