edoxaban and Respiratory-Distress-Syndrome

We aimed to investigate the clinical performance of edoxaban for the treatment of pulmonary embolism (PE) in hospitalized COVID-19 patients.. We conducted a retrospective analysis selecting hospitalized patients with COVID-19 admitted to our Institution from 20 May 2020 to 20 November 2020 with computer tomography (CT) detected PE at admission, treated with edoxaban after initial parenteral therapy. Clinical outcomes were compared between patients with and without ARDS at admission and between those with and without CT confirmed PE resolution.. 50 patients were included. Mean follow-up was 42.5 ± 10 days. No baseline differences were found between patients with ARDS (30%) and those without ARDS at admission. Patients with PE resolution (84%) were younger (. Edoxaban was an effective and safe treatment for acute PE in COVID-19 setting.

Topics: Adult; Aged; COVID-19; Factor Xa Inhibitors; Female; Fondaparinux; Humans; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Pulmonary Embolism; Pyridines; Respiratory Distress Syndrome; Retrospective Studies; SARS-CoV-2; Thiazoles