edetic acid has been researched along with Disease Models, Animal in 130 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 21 (16.15) | 18.7374 |
1990's | 30 (23.08) | 18.2507 |
2000's | 37 (28.46) | 29.6817 |
2010's | 33 (25.38) | 24.3611 |
2020's | 9 (6.92) | 2.80 |
Authors | Studies |
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Abouelhassan, Y; Chojnacki, M; Ding, Y; Dunman, PM; Fuse, MA; Huang, G; Huigens, RW; Jin, S; Kallifidas, D; Kundra, S; Lemos, JA; Liu, K; Luesch, H; Rohde, KH; Yang, H; Zhang, P | 1 |
Chae, IH; Han, D; Kang, SH; Yoon, CH; Youn, TJ | 1 |
Boateng, YO; Donnelly, WT; Erlichman, JS; Estevez, AY; Ganesana, M; Leiter, JC; Li, G; Lipps, JM; Olson, JE; Trentini, JF; Yablonski, SER | 1 |
Aronow, BJ; Bertelli, C; Bogue, AL; Brinkman, FSL; Danilczuk, M; Dasgupta, N; Dexheimer, P; Dongare, P; Forbes, MDE; Gill, E; Hancock, REW; Haslam, DB; Hassett, DJ; Ko, SB; Lau, GW; McDaniel, CT; Meyer, TJ; Miller, WE; Mortensen, JE; Muruve, DA; Panmanee, W; Paul, AT; Schurr, MJ; Winsor, GL | 1 |
Aasbrenn, M; Abd El-Aty, AM; Abdu, A; Abraha, HB; Achour, A; Acquaroni, M; Addeo, P; Agback, P; Agback, T; Al-Alwan, M; Al-Mazrou, A; Al-Mohanna, F; Aliste, M; Almquist, J; Andel, J; Ando, M; Angelov, A; Annuar, MSM; Antwi, K; Arroliga, AC; Arruda, SLM; Asch, SM; Averous, G; Ayaz, S; Ayer, GB; Bachellier, P; Ball, S; Banijamali, AR; Barden, TC; Bartoncini, S; Bedanie, G; Bellò, M; Benić, F; Berhe, GG; Bertiger, G; Beumer, JH; Bhandari, B; Bond, DS; Boules, M; Braüner Christensen, J; Brown-Johnson, C; Burgstaller, S; Cao, L; Capasso, C; Carlevato, R; Carvalho, AE; Ceci, F; Chagas, ATA; Chavan, SG; Chen, AP; Chen, HC; Chen, J; Chen, Q; Chen, Y; Chen, YF; Christ, ER; Chu, CW; Covey, JM; Coyne, GO'; Cristea, MC; Currie, MG; Dahdal, DN; Dai, L; Dang, Z; de Abreu, NL; de Carvalho, KMB; de la Plaza Llamas, R; Deandreis, D; Del Prete, S; Dennis, JA; Deur, J; Díaz Candelas, DA; Divyapriya, G; Djanani, A; Dodig, D; Doki, Y; Doroshow, JH; Dos Santos, RC; Durairaj, N; Dutra, ES; Eguchi, H; Eisterer, W; Ekmann, A; Elakkad, A; Evans, WE; Fan, W; Fang, Z; Faria, HP; Farris, SG; Fenoll, J; Fernandez-Botran, R; Flores, P; Fujita, J; Gan, L; Gandara, DR; Gao, X; Garcia, AA; Garrido, I; Gebru, HA; Gerger, A; Germano, P; Ghamande, S; Ghebeh, H; Giver Jensen, T; Go, A; Goichot, B; Goldwater, M; Gontero, P; Greil, R; Gruenberger, B; Guarneri, A; Guo, Y; Gupta, S; Haxholdt Lunn, T; Hayek, AJ; He, ML; Hellín, P; Hepprich, M; Hernández de Rodas, E; Hill, A; Hndeya, AG; Holdsworth, LM; Hookey, L; Howie, W; Hu, G; Huang, JD; Huang, SY; Hubmann, E; Hwang, SY; Imamura, H; Imperiale, A; Jiang, JQ; Jimenez, JL; Jin, F; Jin, H; Johnson, KL; Joseph, A; Juwara, L; Kalapothakis, E; Karami, H; Karayağiz Muslu, G; Kawabata, R; Kerwin, J; Khan, I; Khin, S; Kidanemariam, HG; Kinders, RJ; Klepov, VV; Koehler, S; Korger, M; Kovačić, S; Koyappayil, A; Kroll, MH; Kuban, J; Kummar, S; Kung, HF; Kurokawa, Y; Laengle, F; Lan, J; Leal, HG; Lee, MH; Lemos, KGE; Li, B; Li, G; Li, H; Li, X; Li, Y; Li, Z; Liebl, W; Lillaz, B; Lin, F; Lin, L; Lin, MCM; Lin, Y; Lin, YP; Lipton, RB; Liu, J; Liu, W; Liu, Z; Lu, J; Lu, LY; Lu, YJ; Ludwig, S; Luo, Y; Ma, L; Ma, W; Machado-Coelho, GLL; Mahmoodi, B; Mahoney, M; Mahvash, A; Mansour, FA; Mao, X; Marinho, CC; Masferrer, JL; Matana Kaštelan, Z; Melendez-Araújo, MS; Méndez-Chacón, E; Miletić, D; Miller, B; Miller, E; Miller, SB; Mo, L; Moazzen, M; Mohammadniaei, M; Montaz-Rosset, MS; Mousavi Khaneghah, A; Mühlethaler, K; Mukhopadhyay, S; Mulugeta, A; Nambi, IM; Navarro, S; Nazmara, S; Neumann, HJ; Newman, EM; Nguyen, HTT; Nicolato, AJPG; Nicolotti, DG; Nieva, JJ; Nilvebrant, J; Nocentini, A; Nugent, K; Nunez-Rodriguez, DL; Nygren, PÅ; Oberli, A; Oderda, M; Odisio, B; Oehler, L; Otludil, B; Overman, M; Özdemir, M; Pace, KA; Palm, H; Parchment, RE; Parise, R; Passera, R; Pavlovic, J; Pecherstorfer, M; Peng, Z; Pérez Coll, C; Petzer, A; Philipp-Abbrederis, K; Pichler, P; Piekarz, RL; Pilati, E; Pimentel, JDSM; Posch, F; Prager, G; Pressel, E; Profy, AT; Qi, P; Qi, Y; Qiu, C; Rajasekhar, B; Ramia, JM; Raynor, HA; Reis, VW; Reubi, JC; Ricardi, U; Riedl, JM; Romano, F; Rong, X; Rubinstein, L; Rumboldt, Z; Sabir, S; Safaeinili, N; Sala, BM; Sandoval Castillo, L; Sau, M; Sbhatu, DB; Schulte, T; Scott, V; Shan, H; Shao, Y; Shariatifar, N; Shaw, JG; She, Y; Shen, B; Shernyukov, A; Sheth, RA; Shi, B; Shi, R; Shum, KT; Silva, JC; Singh, A; Sinha, N; Sirajudeen, AAO; Slaven, J; Sliwa, T; Somme, F; Song, S; Steinberg, SM; Subramaniam, R; Suetta, C; Sui, Y; Sun, B; Sun, C; Sun, H; Sun, Y; Supuran, CT; Surger, M; Svartz, G; Takahashi, T; Takeno, A; Tam, AL; Tang, Z; Tanner, JA; Tannich, E; Taye, MG; Tekle, HT; Thomas, GJ; Tian, Y; Tobin, JV; Todd Milne, G; Tong, X; Une, C; Vela, N; Venkateshwaran, U; Villagrán de Tercero, CI; Wakefield, JD; Wampfler, R; Wan, M; Wang, C; Wang, J; Wang, L; Wang, S; Waser, B; Watt, RM; Wei, B; Wei, L; Weldemichael, MY; Wellmann, IA; Wen, A; Wild, D; Wilthoner, K; Winder, T; Wing, RR; Winget, M; Wöll, E; Wong, KL; Wong, KT; Wu, D; Wu, Q; Wu, Y; Xiang, T; Xiang, Z; Xu, F; Xu, L; Yamasaki, M; Yamashita, K; Yan, H; Yan, Y; Yang, C; Yang, H; Yang, J; Yang, N; Yang, Y; Yau, P; Yu, M; Yuan, Q; Zhan, S; Zhang, B; Zhang, H; Zhang, J; Zhang, N; Zhang, Y; Zhao, X; Zheng, BJ; Zheng, H; Zheng, W; Zhou, H; Zhou, X; Zhu, S; Zimmer, DP; Zionts, D; Zitella, A; Zlott, J; Zolfaghari, K; Zuo, D; Zur Loye, HC; Žuža, I | 1 |
Abu-Seida, AM; Bastawy, HA; El Halaby, HM; Farid, MH; Fawzy, MI | 1 |
Amirmozafari, N; Erfani, M; Mazaheri Tehrani, M | 1 |
Austerlitz, T; Baumgartner, M; Beer, A; Cervenka, A; Deim, G; Evstatiev, R; Frick, A; Gasche, C; Gmainer, C; Khare, V; Krnjic, A; Lang, M; Schachner, H | 1 |
Barry, A; Hassett, DJ; Panmanee, W; Satish, L | 1 |
Ansari, NH; Shoeb, M; Syed, MF; Xiao, T; Zhang, M | 1 |
Bao, B; Zheng, X; Zhu, H | 1 |
Awazu, K; Honda, N; Ito, N; Katayama, B; Morimoto, K; Oiso, N; Ozawa, T; Tsuruta, D | 1 |
Kimmitt, BA; Moore, GE; Stiles, J | 1 |
Chowdhury, A; Karamched, SR; Moreland, HE; Nosoudi, N; Vyavahare, NR | 1 |
Cai, XB; Gao, Q; Guo, LL; Huang, C; Qi, XS; Wan, XJ | 1 |
Bentzer, P; Jungner, M; Lundblad, C | 1 |
Liu, Z; Lu, X; Shang, Q | 1 |
Baynes, JW; Frizzell, N | 1 |
Boase, S; Cleland, E; Drilling, A; James, C; Jardeleza, C; Jervis-Bardy, J; Morales, S; Speck, P; Tan, NC; Vreugde, S; Wormald, PJ | 1 |
Wreesmann, CT | 1 |
Baracat, MM; Casagrande, R; da França, LG; Fattori, V; Georgetti, SR; Mizokami, SS; Pavanelli, WR; Silva, JJ; Staurengo-Ferrari, L; Verri, WA; Zanichelli, PG | 1 |
Dandapani, K; Katyal, A; Malairaman, U | 1 |
Blain, PG; Dunn, M; Flecknell, PA; Henderson, D; Hill, SL; Morris, CM; Thomas, AA; Thomas, SH | 1 |
Cai, XB; Dong Yuan, X; Li, BW; Lu, LG; Qi, XS; Qin Qian, Y; Wan, XJ; Wang, XP; Xu, ZJ; Yang, Q; Zhang, RL; Zhang, WX | 1 |
Aizenman, E; Friedman, A; Gilad, D; Hershfinkel, M; Ketzef, M; Sekler, I; Shorer, S | 1 |
Ansari, NH; Ayadi, AE; Enkhbaatar, P; Finnerty, CC; Goswamy, J; Herndon, DN; Mifflin, R; Papaconstantinou, J; Sousse, L; Wang, CZ | 1 |
Borlee, BR; Borlee, GI; Ferris, RA; Hennet, ML; Loncar, KD; McCue, PM | 1 |
He, Y; Li, F; Lin, Y; Liu, Z; Lu, Q; Song, C; Wang, Z; Yu, J | 1 |
Bruton, J; Cacciani, N; Cheng, AJ; Ivarsson, N; Jonsson, W; Larsson, L; Llano-Diez, M; Sun, V; Westerblad, H | 1 |
Chowdhury, A; Gerard, P; Karamched, S; Nosoudi, N; Parasaram, V; Parrish, J; Siclari, S; Vyavahare, N | 1 |
Kim, TY; Kim, YH; Kim, YJ; Koh, JY; Lee, JY | 1 |
Jarrett, SG; Liang, LP; Patel, M | 1 |
Bosmans, H; Chen, F; DeKeyzer, F; Feng, Y; Li, J; Marchal, G; Ni, Y; Wang, H; Yu, J | 1 |
Bovee-Oudenhoven, IM; Brummer, RJ; Hendriks, T; Keijer, J; Kramer, E; Schepens, MA; Schonewille, AJ; van der Meer, R; van Schothorst, EM; Vink, C | 1 |
Arribas, SM; Bernatova, I; Conde, MV; González, MC; Kopincova, J; Puzserova, A | 1 |
Chen, M; Chen, Q; Cheng, XW; Jia, JM; Liu, HX; Lu, TJ; Xiong, ZQ; Xu, L; Zhang, C | 1 |
Myint, KT; Nakamura, T; Oda, Y | 1 |
Cui, X; Shi, Q; Yang, XQ | 1 |
Brazier, MW; Collins, SJ; Green, JE; Han, S; Hill, AF; Kvasnicka, M; Masters, CL; Underwood, JR; Volitakis, I; White, AR | 1 |
Ansari, NH; Campbell, GA; Hogan, D; Liu, P; Shoeb, M; Wong, IG; Xiao, T; Zhang, M | 1 |
Duggan, D; Lee, SM; Nagaoka, H; Teixeira, FB; Yamauchi, M; Yamauchi, N; Yamauchi, S; Zhong, S | 1 |
Benvegnú, D; Boufleur, N; Bürger, ME; Dias, VT; Dos Santos, CM; Flores, EM; Pase, CS; Reckziegel, P; Segat, HJ; Silva Barcelos, RC | 1 |
Gutiérrez, JM; Herrera, C; Rucavado, A; Warrell, DA | 1 |
Harada, S; Ishii, Y; Kimura, S; Livermore, DM; Saga, T; Tateda, K; Woodford, N; Yamaguchi, K; Yoshizumi, A | 1 |
Aguilera-Tejero, E; Cantor, T; Estepa, JC; Felsenfeld, AJ; Gao, P; Lopez, I; Rodríguez, M | 1 |
Ailawadi, G; Bishop, K; Ford, JW; Hannawa, KK; Henke, PK; Knipp, BS; Lu, G; Roelofs, KJ; Stanley, JC; Thanaporn, P; Upchurch, GR | 1 |
Ma, QY; Rowlands, BJ; Williamson, KE | 1 |
Glancy, R; Hodge, AJ; Neethling, WM | 1 |
Jessen, KR; Matsas, R; Meintanis, S; Mirsky, R; Thomaidou, D | 1 |
Choi, JW; Gong, GY; Kim, ST; Kim, TH; Lim, TH; Seo, JB; Shin, JH; Yang, DH; Yoon, JH | 1 |
Choi, JW; Kim, ST; Kim, TH; Lim, TH; Seo, JB; Shin, JH; Yang, DH; Yoon, JH | 1 |
Massry, SG; Smogorzewski, M | 1 |
Bonnefont-Rousselot, D; Jafarian-Tehrani, M; Lerouet, D; Louin, G; Margaill, I; Palmier, B; Plotkine, M | 1 |
Stauber, WT; Willems, ME | 1 |
Hazell, AS; Kennedy, G; Norenberg, MD; Normandin, L; Yi, JH | 1 |
Kuo, YM; Wu, Z; Yang, Y; Zhou, B | 1 |
Nadler, JV; Timofeeva, O | 1 |
Belloni, D; Ferrero, E; Ferrero, ME; Foglieni, C; Fulgenzi, A; Pellegatta, F; Sciorati, C; Ticozzi, P | 1 |
Bahna, P; Hachem, R; Hanna, H; Raad, I; Stephens, LC | 1 |
Cheng, C; Inoue, T; Kang, Y; Nagashima, Y; Nakagami, Y; Oka, T; Omura, M; Suzuki, A | 1 |
Aronson, M; Dalal, E; Hidas, G; Nativ, O | 1 |
Danscher, G; Jensen, MS; Noyan, B | 1 |
Bentzer, P; Lundblad, C | 1 |
Chen, H; Levin, L; Ritter, AL; Teixeira, FB; Trope, M | 1 |
Alarie, Y; Valentini, JE; Wong, KL | 1 |
Alving, K; Fornhem, C; Lundberg, JM | 1 |
el-Badawy, S; Nielsen, OS; Overgaard, J; Safwat, A | 1 |
Aiko, S; Grisham, MB | 1 |
Chang, KK; Chen, CY; Chou, TC; Chow, NH; Leow, TC; Lin, XZ | 1 |
Kaku, H; Kurokawa, R; Morisada, M; Onodera, T; Yamaguchi, H | 1 |
Burney, DL; Crissinger, KD; Gonzalez, E; Velasquez, OR | 1 |
Bustamante, SA; Chotinaruemol, S; Clark, DA; McIntyre, JA; Miller, MJ; Sadowska-Krowicka, H; Zhang, XJ | 1 |
Blomlöf, J; Blomlöf, L; Jansson, L; Lindskog, S | 1 |
Aguilera-Tejero, E; Almadén, Y; Felsenfeld, AJ; Mayer-Valor, R; Rodríguez, M; Sánchez, J | 1 |
Callegan, MC; Engel, LS; Folkens, AT; Hill, JM; O'Callaghan, RJ; Shimomura, Y | 1 |
McHugh, KJ; Persson, CG; Svensjö, E | 1 |
Marchal, G; Ni, Y | 1 |
Atzpodien, E; Grant, D; Martinsen, I; Toft, KG | 1 |
Karlsson, JO; Mortensen, E; Pedersen, HK; Refsum, H; Sager, G | 1 |
Buret, AG; Gall, DG; Hardin, JA; Kimm, MH; Olson, ME | 1 |
Baert, AL; Grant, D; Gray, TJ; Lukito, G; Marchal, G; Ni, Y; Petré, C | 1 |
Barrett, KE; Ries, J; Stein, J | 1 |
Sakurai, H; Tsuji, A | 1 |
Baumgarten, KM; Gerstenblith, G; Weiss, RG | 1 |
Harmeyer, J; Schlumbohm, C | 1 |
Daniel, RC; Enemark, JM; Jørgensen, RJ; Mellau, LS; Nyengaard, NR | 1 |
Han, JA; Kim, KM; Kim, SS; Kim, YM; Lea, HZ; Yoo, YM | 1 |
Andersson, SE; Ekström, GM | 1 |
Dolphin, PJ; Kelly, SE; O'Brien, SF; Russell, JC | 1 |
Arheden, H; Bremerich, J; Higgins, CB; Saeed, M; Wendland, MF | 1 |
Dwivedi, SK; Patra, RC; Swarup, D | 1 |
Belinsky, SA; March, TH; Marron-Terada, PG | 1 |
Barat, JL; Clofent-Sanchez, G; Dabadie, M; Ducassou, D; Jacobin, MJ; Laroche-Traineau, J; Nurden, AT; Valli, N | 1 |
Brurok, H; Engebretsen, B; Eriksen, M; Jynge, P; Karlsson, JO; Moen, O; Refsum, H; Toft, KG; Towart, R | 1 |
Hachem, R; Raad, I; Sherertz, R; Tcholakian, RK | 1 |
Bergeron, RJ; Brittenham, GM; Wiegand, J | 1 |
Arroyo, M; Barrientos, A; Blanco, J; Cano, M; Fernández, C; Ortega, L; Prats, D; Sánchez-Fructuoso, AI | 1 |
Howell, RL; Lees, RK; MacDonald, HR | 1 |
Bingen, A; Kirn, A | 1 |
Allard, R; Berenholc, S; Lamendin, H; Moczar, E; Robert, AM | 1 |
Edgerton, MT; Edlich, RF; Pettry, D; Rodeheaver, GT; Thacker, JG | 1 |
Askenazi, J; Davis, MA; Holman, BL; Jones, AG; Maroko, PR | 1 |
Ballowitz, L; Hanefeld, F | 1 |
Brown, SI; Gipson, LL; Kessler, E; Mondino, BJ | 1 |
Arai, H; Ariji, F; Asoo, N; Ishikawa, T; Konno, K; Matsuda, T; Motomiya, M; Nagai, H; Nakamura, T; Niwa, T; Sato, H; Yokosawa, A | 1 |
Abou-Shousha, EK; el-Sahn, MF; Korra, AK | 1 |
Chansue, E; Gans, LA; Laycock, KA; Lenze, EJ; Miller, JK; Pepose, JS; Smith, ME | 1 |
Hiromasa, S; Kupersmith, J; Li, ZY; Maldonado, C; Zee-Cheng, C | 1 |
Horton, JW | 1 |
Barkemeyer, B; Clark, DA; Eloby-Childress, S; Gu, X; Miller, MJ; Sadowska-Krowicka, H; Zhang, XJ | 1 |
Chamorovskaia, LT; MItrokhin, NM; Zhigacheva, IV | 1 |
Batt, RM; Hall, EJ | 1 |
Banerjee, AK; Peters, TJ | 1 |
Daniel, RC; Fennwick, DC | 1 |
Ehrlich, MG; Ishizue, KK; Mankin, HJ | 1 |
Ehrlich, MG | 1 |
Bonucci, E; Sadun, R | 1 |
Burrous, SE; Eudy, WW; Siedler, AJ | 1 |
Weiser, R | 1 |
Okumoto, M; Smolin, G; Wilson, FM | 1 |
Feine, U; Geisbe, H; Mildenberger, H; Schmidt, HT; Schubert, GE; Wahl, SH | 1 |
Bohigian, G; Caraway, BL; Okumoto, M; Valenton, M | 1 |
Frank, MM; Schreiber, AD | 1 |
Brázdová, K; Mráz, J; Nezval, J; Sedlácek, J | 1 |
Arora, P; Chellappan, DK; Dua, K; Gupta, G; Nainwal, LM; Oliver, BG; Singh, SK | 1 |
Bhandari, R; Kuhad, A; Prasad, RS; Prasad, SK; Shakya, A; Sinha, SK; Verma, S | 1 |
Ahmad, S; Arooj, M; Butt, TT; Gan, SH; Jafar, TH; Malik, A; Mirza, MU; Waquar, S; Zahid, F; Zahid, S | 1 |
Chang, W; Li, Y; Lou, H; Ying, Z; Zhang, M | 1 |
Chauhan, K; Parmar, S; Ranpariya, V; Sheth, N | 1 |
5 review(s) available for edetic acid and Disease Models, Animal
Article | Year |
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Reasons for raising the maximum acceptable daily intake of EDTA and the benefits for iron fortification of foods for children 6-24 months of age.
Topics: Animals; Biological Availability; Child, Preschool; Disease Models, Animal; Dose-Response Relationship, Drug; Edetic Acid; Food, Fortified; Humans; Infant; Iron, Dietary; Rats; Recommended Dietary Allowances; Zinc | 2014 |
Endothelial dysfunction in spontaneously hypertensive rats: focus on methodological aspects.
Topics: Animals; Antioxidants; Ascorbic Acid; Blood Pressure; Disease Models, Animal; Edetic Acid; Endothelium, Vascular; Hypertension; Nitric Oxide; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity | 2009 |
Clinical implications of studies with MnDPDP in animal models of hepatic abnormalities.
Topics: Animals; Contrast Media; Disease Models, Animal; Drug Evaluation, Preclinical; Edetic Acid; Humans; Liver; Liver Diseases; Magnetic Resonance Imaging; Manganese; Pyridoxal Phosphate | 1997 |
Induced hypocalcaemia by Na2EDTA infusion. A review.
Topics: Animals; Calcium; Cattle; Cattle Diseases; Disease Models, Animal; Edetic Acid; Female; Heart; Hypocalcemia; Muscle, Smooth; Parturient Paresis; Pregnancy | 1999 |
Collagenase inhibitors: rationale for their use in treating corneal ulceration.
Topics: Acetylcysteine; alpha 1-Antitrypsin; alpha-Macroglobulins; Animals; Calcium; Corneal Ulcer; Cyclic AMP; Cysteine; Disease Models, Animal; Edetic Acid; Humans; Microbial Collagenase; Protease Inhibitors; Steroids; Tropocollagen; Zinc Radioisotopes | 1975 |
1 trial(s) available for edetic acid and Disease Models, Animal
124 other study(ies) available for edetic acid and Disease Models, Animal
Article | Year |
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A Modular Synthetic Route Involving
Topics: Aniline Compounds; Animals; Anti-Bacterial Agents; Biofilms; Cell Line; Cell Survival; Disease Models, Animal; Drug Design; Female; Halogenation; Humans; Iron; Iron Deficiencies; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Phenazines; Staphylococcal Infections; Structure-Activity Relationship; Wound Healing | 2021 |
Attenuation of ischemia-reperfusion injury by intracoronary chelating agent administration.
Topics: Animals; Aorta, Thoracic; Chelating Agents; Disease Models, Animal; Echocardiography; Edetic Acid; Male; Mitochondria; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Salvage Therapy; Stroke Volume; Swine; Ventricular Function, Left; Ventricular Remodeling | 2022 |
Antioxidant Enzyme-Mimetic Activity and Neuroprotective Effects of Cerium Oxide Nanoparticles Stabilized with Various Ratios of Citric Acid and EDTA.
Topics: Animals; Antioxidants; Catalase; Cell Death; Cerium; Citric Acid; Disease Models, Animal; Edetic Acid; Hippocampus; Ischemia; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nanoparticles; Neuroprotective Agents; Oxidative Stress; Oxidoreductases; Particle Size; Superoxide Dismutase; Surface Properties | 2019 |
AB569, a nontoxic chemical tandem that kills major human pathogenic bacteria.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Biofilms; Disease Models, Animal; Down-Regulation; Drug Resistance, Bacterial; Edetic Acid; Lung Diseases; Metabolic Networks and Pathways; Mice; Nitrites; Pseudomonas aeruginosa; Sodium Nitrite | 2020 |
Evaluation of the regenerative potential of dentin conditioning and naturally derived scaffold for necrotic immature permanent teeth in a dog model.
Topics: Animals; Dental Pulp; Dental Pulp Necrosis; Dentin; Disease Models, Animal; Dogs; Edetic Acid; Female; Humans; Male; Odontoblasts; Platelet-Rich Fibrin; Regeneration; Tissue Engineering; Tissue Scaffolds; Tooth Root | 2020 |
[
Topics: Animals; Antimicrobial Cationic Peptides; Disease Models, Animal; Drug Stability; Edetic Acid; Escherichia coli; Escherichia coli Infections; Hydrazines; Kidney; Mice; Nicotinic Acids; Radiopharmaceuticals; Technetium; Tissue Distribution | 2021 |
The food additive EDTA aggravates colitis and colon carcinogenesis in mouse models.
Topics: Animals; Carcinogenesis; Colitis; Colonic Neoplasms; Disease Models, Animal; Edetic Acid; Food Additives; Humans; Inflammatory Bowel Diseases; Interleukin-10; Mice; Mice, Knockout | 2021 |
AB569, a Novel, Topical Bactericidal Gel Formulation, Kills Pseudomonas aeruginosa and Promotes Wound Healing in a Murine Model of Burn Wound Infection.
Topics: Animals; Anti-Bacterial Agents; Body Weight; Burns; Collagen; Disease Models, Animal; Edetic Acid; Gels; Nitric Oxide; Nitrites; Pseudomonas aeruginosa; Pseudomonas Infections; Wound Healing | 2021 |
Amelioration of Endotoxin-Induced Inflammatory Toxic Response by a Metal Chelator in Rat Eyes.
Topics: Animals; Aqueous Humor; Calcium Chelating Agents; Cytokines; Disease Models, Animal; Edetic Acid; Male; Oxidative Stress; Rats; Rats, Inbred Lew; Uveitis | 2018 |
Is NS-EDTA Effective in Clearing Bacteria From Infected Wounds in a Rat Model?
Topics: Animals; Anti-Infective Agents; Cell Survival; Cells, Cultured; Debridement; Disease Models, Animal; Edetic Acid; Escherichia coli Infections; Fibroblasts; Human Umbilical Vein Endothelial Cells; Humans; Rats; Saline Solution; Staphylococcal Infections; Surgical Wound Infection; Therapeutic Irrigation; Time Factors | 2018 |
Enhanced sterilization and healing of cutaneous pseudomonas infection using 5-aminolevulinic acid as a photosensitizer with 410-nm LED light.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Biofilms; Biopsy; Disease Models, Animal; Edetic Acid; Humans; Levulinic Acids; Male; Mice; Mice, Inbred C57BL; Photochemotherapy; Photosensitizing Agents; Pseudomonas aeruginosa; Pseudomonas Infections; Skin; Skin Ulcer; Wound Healing | 2018 |
Comparison of the efficacy of various concentrations and combinations of serum, ethylenediaminetetraacetic acid, tetracycline, doxycycline, minocycline, and N-acetylcysteine for inhibition of collagenase activity in an in vitro corneal degradation model.
Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Collagenases; Cornea; Corneal Diseases; Disease Models, Animal; Dogs; Doxycycline; Edetic Acid; Horses; Matrix Metalloproteinase Inhibitors; Minocycline; Serum; Tetracycline | 2018 |
Site-specific chelation therapy with EDTA-loaded albumin nanoparticles reverses arterial calcification in a rat model of chronic kidney disease.
Topics: Animals; Aorta; Arteries; Body Weight; Bone and Bones; Chelation Therapy; Disease Models, Animal; Edetic Acid; Kidney; Matrix Metalloproteinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nanoparticles; Phenotype; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Serum Albumin, Bovine; Tissue Distribution; Vascular Calcification | 2019 |
Drug-eluting fully covered self-expanding metal stent for dissolution of bile duct stones
Topics: Alloys; Animals; Common Bile Duct; Disease Models, Animal; Drug Carriers; Drug Liberation; Drug-Eluting Stents; Edetic Acid; Gallstones; Humans; Male; Nanofibers; Polyesters; Self Expandable Metallic Stents; Sodium Cholate; Swine; Swine, Miniature; Treatment Outcome | 2019 |
Rosuvastatin in experimental brain trauma: improved capillary patency but no effect on edema or cerebral blood flow.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood-Brain Barrier; Brain Edema; Brain Injuries; Capillaries; Cerebrovascular Circulation; Disease Models, Animal; Edetic Acid; Epoprostenol; Fluorobenzenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Microcirculation; Nitric Oxide; Pyrimidines; Rats; Rats, Sprague-Dawley; Rosuvastatin Calcium; Sulfonamides; Time Factors | 2013 |
[Experimental study on quick preparation of osteoporosis in vitro model].
Topics: Animals; Biomechanical Phenomena; Bone Density; Decalcification Technique; Disease Models, Animal; Edetic Acid; Female; Femur; Goats; Osteoporosis; Tensile Strength; Time Factors; Tomography, X-Ray Computed | 2013 |
Chelation therapy: overlooked in the treatment and prevention of diabetes complications?
Topics: Advanced Oxidation Protein Products; Animals; Cardiovascular Diseases; Catalysis; Chelation Therapy; Diabetes Complications; Diabetes Mellitus, Type 2; Disease Models, Animal; Edetic Acid; Glycation End Products, Advanced; Humans; Metals; Reactive Oxygen Species | 2013 |
Safety and efficacy of topical bacteriophage and ethylenediaminetetraacetic acid treatment of Staphylococcus aureus infection in a sheep model of sinusitis.
Topics: Animals; Biofilms; Cattle; Disease Models, Animal; Edetic Acid; Frontal Sinus; Humans; Microscopy, Confocal; Sheep; Staphylococcal Infections; Staphylococcus aureus; Staphylococcus Phages | 2014 |
The ruthenium nitric oxide donor, [Ru(HEDTA)NO], inhibits acute nociception in mice by modulating oxidative stress, cytokine production and activating the cGMP/PKG/ATP-sensitive potassium channel signaling pathway.
Topics: Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Edetic Acid; Hyperalgesia; Inflammation; KATP Channels; Male; Mice; Nitric Oxide; Nitric Oxide Donors; Nociception; Oxidative Stress; Ruthenium Compounds; Signal Transduction | 2014 |
Effect of Ca2EDTA on zinc mediated inflammation and neuronal apoptosis in hippocampus of an in vivo mouse model of hypobaric hypoxia.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Chelating Agents; Disease Models, Animal; Edetic Acid; Gene Expression Regulation; Hippocampus; Homeostasis; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; In Situ Nick-End Labeling; Inflammation; Inflammation Mediators; Lipid Peroxidation; Male; Mice, Inbred BALB C; NADPH Oxidases; Neurons; Nitric Oxide; Nitrites; Poly(ADP-ribose) Polymerases; Zinc | 2014 |
Rapid and equivalent systemic bioavailability of the antidotes HI-6 and dicobalt edetate via the intraosseous and intravenous routes.
Topics: Animals; Antidotes; Area Under Curve; Biological Availability; Chemical Warfare Agents; Disease Models, Animal; Edetic Acid; Infusions, Intraosseous; Injections, Intravenous; Oximes; Pyridinium Compounds; Swine | 2015 |
Safety and efficacy of a novel plastic stent coated with stone-dissolving agents for the treatment of biliary stones in a porcine model.
Topics: Alanine Transaminase; Amylases; Animals; Aspartate Aminotransferases; Calcium Chelating Agents; Cholangiography; Disease Models, Animal; Drug-Eluting Stents; Edetic Acid; Gallstones; Leukocyte Count; Plastics; Sodium Cholate; Swine | 2015 |
Homeostatic regulation of KCC2 activity by the zinc receptor mZnR/GPR39 during seizures.
Topics: Action Potentials; Animals; Animals, Newborn; Disease Models, Animal; Edetic Acid; Excitatory Amino Acid Agonists; Fluoresceins; Gamma Rhythm; Gene Expression Regulation; Hippocampus; Homeostasis; In Vitro Techniques; K Cl- Cotransporters; Kainic Acid; Mice; Mice, Transgenic; Protein Transport; Receptors, G-Protein-Coupled; Seizures; Statistics, Nonparametric; Symporters; Zinc | 2015 |
Topically applied metal chelator reduces thermal injury progression in a rat model of brass comb burn.
Topics: Acrolein; Administration, Cutaneous; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Animals; Burns; Chelating Agents; Copper; Dimethyl Sulfoxide; Disease Models, Animal; Edetic Acid; Immunohistochemistry; Malondialdehyde; Mitochondrial Proteins; Oxidative Stress; Permeability; Rats; Retinal Dehydrogenase; Skin; Sulfones; Trauma Severity Indices; Zinc | 2015 |
In Vitro Efficacy of Nonantibiotic Treatments on Biofilm Disruption of Gram-Negative Pathogens and an In Vivo Model of Infectious Endometritis Utilizing Isolates from the Equine Uterus.
Topics: Acetylcysteine; Animals; Anti-Infective Agents; Biofilms; Biomass; Disease Models, Animal; Edetic Acid; Endometritis; Female; Gram-Negative Bacteria; Horses; Hydrogen Peroxide; Luminescent Measurements; Microbial Viability; Staining and Labeling; Uterus | 2016 |
In vitro and in vivo activity of EDTA and antibacterial agents against the biofilm of mucoid Pseudomonas aeruginosa.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Disease Models, Animal; Edetic Acid; Guinea Pigs; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections | 2017 |
Impaired Ca(2+) release contributes to muscle weakness in a rat model of critical illness myopathy.
Topics: Animals; Critical Illness; Disease Models, Animal; Edetic Acid; Female; Male; Muscle Contraction; Muscle Strength; Muscle Weakness; Muscular Diseases; Rats; Rats, Sprague-Dawley | 2016 |
Reversal of Vascular Calcification and Aneurysms in a Rat Model Using Dual Targeted Therapy with EDTA- and PGG-Loaded Nanoparticles.
Topics: Animals; Aortic Aneurysm; Arachnida; Calcium Chelating Agents; Disease Models, Animal; Drug Therapy, Combination; Edetic Acid; Histocytochemistry; Hydrolyzable Tannins; Nanoparticles; Polyphenols; Rats; Treatment Outcome; Vascular Calcification | 2016 |
Essential role for zinc-triggered p75NTR activation in preconditioning neuroprotection.
Topics: Animals; Apoptosis; Calcium; Cell Culture Techniques; Cerebral Cortex; Cerebral Infarction; Chelating Agents; Disease Models, Animal; Edetic Acid; Embryo, Mammalian; Enzyme Activation; Excitatory Amino Acid Agonists; Infarction, Middle Cerebral Artery; Ischemic Preconditioning; Laser-Doppler Flowmetry; Male; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Receptor, Nerve Growth Factor; Time Factors; Zinc | 2008 |
Chelation of mitochondrial iron prevents seizure-induced mitochondrial dysfunction and neuronal injury.
Topics: Analysis of Variance; Animals; Behavior, Animal; Bleomycin; Chelating Agents; Colorimetry; Disease Models, Animal; DNA, Mitochondrial; Edetic Acid; Fluoresceins; Glutathione; Glutathione Disulfide; Hippocampus; Iron; Kainic Acid; Male; Mitochondrial Diseases; Organic Chemicals; Rats; Rats, Sprague-Dawley; Status Epilepticus; Subcellular Fractions; Time Factors | 2008 |
Tumor models and specific contrast agents for small animal imaging in oncology.
Topics: Animals; Biomarkers, Tumor; Clinical Trials as Topic; Contrast Media; Diagnostic Imaging; Disease Models, Animal; Edetic Acid; Humans; Image Enhancement; Liver Neoplasms; Magnetic Resonance Imaging; Models, Animal; Molecular Diagnostic Techniques; Neoplasm Transplantation; Neoplasms, Experimental; Pyridoxal Phosphate; Rhabdomyosarcoma | 2009 |
Supplemental calcium attenuates the colitis-related increase in diarrhea, intestinal permeability, and extracellular matrix breakdown in HLA-B27 transgenic rats.
Topics: Animals; Anti-Inflammatory Agents; Calcium; Calcium, Dietary; Colitis; Colon; Diarrhea; Dietary Supplements; Disease Models, Animal; Edetic Acid; Extracellular Matrix; Feces; Female; Fibronectins; Gene Expression; HLA-B27 Antigen; Interleukin-1beta; Intestinal Absorption; Matrix Metalloproteinases; Oligonucleotide Array Sequence Analysis; Permeability; Procollagen; Rats; Rats, Transgenic | 2009 |
Zn2+ mediates ischemia-induced impairment of the ubiquitin-proteasome system in the rat hippocampus.
Topics: Actins; Animals; CA1 Region, Hippocampal; Cells, Cultured; Chelating Agents; Coumarins; Disease Models, Animal; Dose-Response Relationship, Drug; Edetic Acid; Embryo, Mammalian; Enzyme Inhibitors; Fluorescent Dyes; Green Fluorescent Proteins; Imidazoles; Ischemia; Leupeptins; Male; Microtubule-Associated Proteins; Neurons; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Proteasome Endopeptidase Complex; Pyrimidines; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Time Factors; Transfection; Ubiquitin; Zinc | 2009 |
Ethylenediaminetetraacetic acid increases identification rate of phosphoproteomics in real biological samples.
Topics: Alzheimer Disease; Animals; Brain Chemistry; Chromatography, Affinity; Disease Models, Animal; Edetic Acid; Humans; Mass Spectrometry; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphoproteins; Phosphoric Acids; Proteomics; Titanium | 2010 |
The effects of FeCl₃ and Fe-EDTA on the development of psoriasis.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Edetic Acid; Epithelial Cells; Female; Ferric Compounds; Ferrous Compounds; Kidney; Liver; Male; Mice; Mice, Inbred Strains; Psoriasis; Tissue Distribution; Trace Elements | 2011 |
Manganese chelation therapy extends survival in a mouse model of M1000 prion disease.
Topics: Animals; Brain; Chelating Agents; Disease Models, Animal; Edetic Acid; Manganese; Mice; Mice, Inbred BALB C; Prion Diseases; PrPSc Proteins | 2010 |
Topical metal chelation therapy ameliorates oxidation-induced toxicity in diabetic cataract.
Topics: Administration, Topical; Aldehydes; Animals; Cataract; Cell Proliferation; Chelating Agents; Chelation Therapy; Diabetes Complications; Dimethyl Sulfoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Edetic Acid; Epithelial Cells; Lens, Crystalline; Male; Metals; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sulfones | 2011 |
Tissue engineering strategies for immature teeth with apical periodontitis.
Topics: Animals; Apexification; Blood Coagulation; Calcification, Physiologic; Cementogenesis; Chelating Agents; Collagen Type I; Dental Pulp Cavity; Dental Pulp Necrosis; Dentin; Disease Models, Animal; Dogs; Edetic Acid; Guided Tissue Regeneration; Periapical Periodontitis; Random Allocation; Root Canal Preparation; Time Factors; Tissue Engineering; Tissue Scaffolds; Tooth Apex; Wound Healing | 2011 |
Locomotor damage and brain oxidative stress induced by lead exposure are attenuated by gallic acid treatment.
Topics: Animals; Antioxidants; Behavior, Animal; Brain; Catalase; Chelating Agents; Disease Models, Animal; Edetic Acid; Exploratory Behavior; Gallic Acid; Lead; Lead Poisoning, Nervous System; Lipid Peroxidation; Male; Motor Activity; Nitrates; Oxidative Stress; Porphobilinogen Synthase; Protein Carbonylation; Rats; Rats, Wistar | 2011 |
Systemic effects induced by the venom of the snake Bothrops caribbaeus in a murine model.
Topics: Animals; Bothrops; Coagulants; Crotalid Venoms; Disease Models, Animal; Edetic Acid; Fibrinogen; Hemorrhage; Humans; Injections, Intravenous; Lectins, C-Type; Longevity; Lung Diseases; Male; Metalloproteases; Mice; Platelet Aggregation; Species Specificity; Thrombocytopenia; Thrombosis | 2013 |
Efficacies of calcium-EDTA in combination with imipenem in a murine model of sepsis caused by Escherichia coli with NDM-1 β-lactamase.
Topics: Animals; Anti-Bacterial Agents; Bacterial Load; beta-Lactam Resistance; beta-Lactamases; Colony Count, Microbial; Disease Models, Animal; Edetic Acid; Escherichia coli; Escherichia coli Infections; Imipenem; Mice; Microbial Sensitivity Tests; Sepsis | 2013 |
Dynamics of secretion and metabolism of PTH during hypo- and hypercalcaemia in the dog as determined by the 'intact' and 'whole' PTH assays.
Topics: Animals; Calcium Chloride; Disease Models, Animal; Dogs; Edetic Acid; Female; Hypercalcemia; Hypocalcemia; Immunoradiometric Assay; Infusions, Intravenous; Kidney; Male; Parathyroid Hormone; Peptide Fragments | 2003 |
A nonintrinsic regional basis for increased infrarenal aortic MMP-9 expression and activity.
Topics: Actins; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Blood Pressure; Chelating Agents; Disease Models, Animal; Edetic Acid; Gelatin; Gelatinases; Heart Rate; Leupeptins; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Models, Cardiovascular; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1 | 2003 |
Ethylene diamine tetraacetic acid-induced colonic crypt cell proliferation in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Bromodeoxyuridine; Cell Division; Chelating Agents; Colon; Colorectal Neoplasms; Disease Models, Animal; Edetic Acid; Male; Rats; Rats, Wistar | 2004 |
ADAPT-treated porcine valve tissue (cusp and wall) versus Medtronic Freestyle and Prima Plus: crosslink stability and calcification behavior in the subcutaneous rat model.
Topics: Animals; Aortic Valve; Bioprosthesis; Calcinosis; Calcium; Cellulose; Cross-Linking Reagents; Disease Models, Animal; Drug Combinations; Durable Medical Equipment; Edetic Acid; Fixatives; Glutaral; Heart Valve Prosthesis; Male; Models, Cardiovascular; Prosthesis Design; Rats; Rats, Wistar; Severity of Illness Index; Swine; Thimerosal | 2004 |
Novel method for studying myelination in vivo reveals that EDTA is a potent inhibitor of myelin protein and mRNA expression during development of the rat sciatic nerve.
Topics: Animals; Animals, Newborn; Chelating Agents; Disease Models, Animal; DNA-Binding Proteins; Down-Regulation; Drug Carriers; Early Growth Response Protein 2; Edetic Acid; Galactosylceramides; Growth Inhibitors; Implants, Experimental; Microscopy, Electron, Transmission; Myelin Basic Protein; Myelin P0 Protein; Myelin Proteins; Myelin Sheath; Nerve Regeneration; Neurosurgical Procedures; Rats; RNA, Messenger; Schwann Cells; Sciatic Nerve; Silicone Elastomers; Transcription Factors | 2004 |
Manganese dipyridoxyl diphosphate (MnDPDP)-enhanced magnetic resonance imaging of acute reperfused myocardial injury in a cat model: part I: comparison with pathologic examination.
Topics: Acute Disease; Animals; Cats; Contrast Media; Disease Models, Animal; Edetic Acid; Magnetic Resonance Imaging; Myocardial Reperfusion Injury; Pyridoxal Phosphate | 2005 |
Manganese dipyridoxyl diphosphate (MnDPDP)-enhanced magnetic resonance imaging of acute reperfused myocardial injury in a cat model: part II: comparison with cine magnetic resonance imaging.
Topics: Acute Disease; Animals; Cats; Contrast Media; Disease Models, Animal; Edetic Acid; Magnetic Resonance Imaging; Magnetic Resonance Imaging, Cine; Myocardial Reperfusion Injury; Pyridoxal Phosphate | 2005 |
The effects of serum calcium and parathyroid hormone and the interaction between them on blood pressure in normal subjects and in patients with chronic kidney failure.
Topics: Animals; Blood Pressure; Calcium; Disease Models, Animal; Drug Interactions; Edetic Acid; Humans; Hypercalcemia; Hyperparathyroidism; Hypertension; Kidney Failure, Chronic; Parathyroid Hormone; Peptide Fragments | 2005 |
Lack of iNOS induction in a severe model of transient focal cerebral ischemia in rats.
Topics: Amidines; Analysis of Variance; Animals; Anticoagulants; Benzylamines; Blotting, Western; Brain; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Edetic Acid; Enzyme Inhibitors; Inhibitory Concentration 50; Ischemic Attack, Transient; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors | 2005 |
Streptomycin and EDTA decrease the number of desmin-negative fibers following stretch injury.
Topics: Animals; Calcium; Calcium Signaling; Chelating Agents; Desmin; Disease Models, Animal; Down-Regulation; Edetic Acid; Female; Isometric Contraction; Muscle Fibers, Skeletal; Muscle Weakness; Muscle, Skeletal; Muscular Diseases; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Recovery of Function; Streptomycin; Treatment Outcome | 2005 |
Alzheimer type II astrocytic changes following sub-acute exposure to manganese and its prevention by antioxidant treatment.
Topics: Acetylcysteine; Alzheimer Disease; Analysis of Variance; Animals; Antioxidants; Astrocytes; Cerebral Cortex; Chelating Agents; Disease Models, Animal; Drug Interactions; Edetic Acid; Male; Manganese; Rats; Rats, Sprague-Dawley; Time Factors | 2006 |
Dietary rescue of fumble--a Drosophila model for pantothenate-kinase-associated neurodegeneration.
Topics: Acetylcysteine; Adenosine Triphosphate; Animal Feed; Animals; Ascorbic Acid; Carnitine; Cloning, Molecular; Creatine; Diet; Disease Models, Animal; Drosophila; Drosophila melanogaster; Edetic Acid; Ginkgo biloba; Heterozygote; Humans; Inosine; Iron; Mutation; Neurodegenerative Diseases; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Transgenes; Vitamin E | 2005 |
Facilitation of granule cell epileptiform activity by mossy fiber-released zinc in the pilocarpine model of temporal lobe epilepsy.
Topics: Action Potentials; Animals; Bicuculline; Chelating Agents; Disease Models, Animal; Drug Interactions; Edetic Acid; Electric Stimulation; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Mossy Fibers, Hippocampal; Neurons; Perforant Pathway; Pilocarpine; Potassium; Rats; Rats, Sprague-Dawley; Zinc | 2006 |
Protective effect of EDTA preadministration on renal ischemia.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Capillary Permeability; Cell Adhesion; Chelating Agents; Creatinine; Disease Models, Animal; Disease Progression; Edetic Acid; Hemodynamics; Ischemia; Kidney; Macrophage-1 Antigen; Male; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha | 2006 |
EDTA as an adjunct antifungal agent for invasive pulmonary aspergillosis in a rodent model.
Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Calcium; Colony Count, Microbial; Confidence Intervals; Creatinine; Disease Models, Animal; Drug Combinations; Drug Evaluation, Preclinical; Drug Therapy, Combination; Edetic Acid; Lung Diseases, Fungal; Male; Phosphatidylcholines; Phosphatidylglycerols; Rats; Rats, Sprague-Dawley; Survival Analysis; Time Factors | 2006 |
Development of an orthotopic transplantation model in nude mice that simulates the clinical features of human lung cancer.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Animals; Carcinoma, Small Cell; Disease Models, Animal; Edetic Acid; Female; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Reproducibility of Results | 2006 |
EDTA-induced urothelial cell shedding for the treatment of superficial bladder cancer in the mouse.
Topics: Administration, Intravesical; Animals; Chelating Agents; Disease Models, Animal; Disease Progression; Edetic Acid; Female; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Treatment Outcome; Urinary Bladder; Urinary Bladder Neoplasms; Urothelium | 2006 |
The lack of effects of zinc and nitric oxide in initial state of pilocarpine-induced seizures.
Topics: Animals; Behavior, Animal; Chelating Agents; Disease Models, Animal; Drug Interactions; Edetic Acid; Enzyme Inhibitors; Functional Laterality; Hippocampus; Injections, Intraventricular; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Zinc | 2007 |
Effects of L-arginine on cerebral blood flow, microvascular permeability, number of perfused capillaries, and brain water content in the traumatized mouse brain.
Topics: Animals; Arginine; Body Water; Brain Injuries; Capillaries; Capillary Permeability; Cerebral Cortex; Cerebrovascular Circulation; Chromium Radioisotopes; Disease Models, Animal; Edetic Acid; Male; Mice; Mice, Inbred C57BL | 2007 |
The effect of intracanal anti-inflammatory medicaments on external root resorption of replanted dog teeth after extended extra-oral dry time.
Topics: Animals; Anti-Inflammatory Agents; Demeclocycline; Dental Alloys; Desiccation; Disease Models, Animal; Dogs; Drug Combinations; Edetic Acid; Epoxy Resins; Glucocorticoids; Gutta-Percha; Nickel; Root Canal Filling Materials; Root Canal Irrigants; Root Canal Preparation; Root Resorption; Sodium Hypochlorite; Time Factors; Titanium; Tooth Avulsion; Tooth Replantation; Triamcinolone Acetonide; Wound Healing | 2008 |
Single-tracer technique to evaluate pulmonary edema and its application to detect the effect of hexamethylene diisocyanate trimer aerosol exposures.
Topics: Aerosols; Animals; Chromium Radioisotopes; Cyanates; Disease Models, Animal; Edetic Acid; Kinetics; Lung; Male; Mice; Pulmonary Alveoli; Pulmonary Circulation; Pulmonary Edema | 1983 |
Allergen-induced late-phase airways obstruction in the pig: the role of endogenous cortisol.
Topics: Airway Obstruction; Airway Resistance; Allergens; Animals; Catecholamines; Disease Models, Animal; Edetic Acid; Epinephrine; Female; Hemodynamics; Hydrocortisone; Hypersensitivity, Delayed; Male; Metyrapone; Norepinephrine; Swine | 1995 |
Late renal damage after total body irradiation and bone marrow transplantation in a mouse model: effect of radiation fractionation.
Topics: Animals; Blood Urea Nitrogen; Bone Marrow Transplantation; Disease Models, Animal; Dose-Response Relationship, Radiation; Edetic Acid; Hematocrit; Kidney Diseases; Male; Mice; Whole-Body Irradiation | 1995 |
Spontaneous intestinal inflammation and nitric oxide metabolism in HLA-B27 transgenic rats.
Topics: Animals; Animals, Genetically Modified; Colitis; Colon; Disease Models, Animal; Edetic Acid; Gastric Mucosa; HLA-B27 Antigen; Ileitis; Ileum; Inflammatory Bowel Diseases; Intestinal Mucosa; Male; Nitrates; Nitric Oxide; Nitrites; Permeability; Peroxidase; Rats; Rats, Inbred F344; Stomach | 1995 |
Toxic effects of cholelitholytic solvents on gallbladder and liver. A piglet model study.
Topics: Animals; Cholelithiasis; Dimethyl Sulfoxide; Disease Models, Animal; Drug Evaluation, Preclinical; Edetic Acid; Ethers; Gallbladder; Liver; Methyl Ethers; Propionates; Solvents; Swine | 1995 |
Peripolar cells in guinea pigs under experimental hyperplasia of juxtaglomerular cells induced by long-term, low-dose calcium condition.
Topics: Animals; Calcium; Chelating Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Edetic Acid; Female; Guinea Pigs; Hyperplasia; Juxtaglomerular Apparatus; Kallikrein-Kinin System; Kidney Diseases; Male; Microscopy, Electron; Renin; Time Factors | 1994 |
An animal model of necrotizing enterocolitis induced by infant formula and ischemia in developing piglets.
Topics: Animal Feed; Animals; Animals, Newborn; Disease Models, Animal; Edetic Acid; Enterocolitis, Pseudomembranous; Female; Food, Formulated; Ileum; Jejunum; Male; Microvilli; Reperfusion Injury; Swine; Triglycerides | 1994 |
Nitric oxide release in response to gut injury.
Topics: Animals; Bile Acids and Salts; Capillary Permeability; Chromium Radioisotopes; Disease Models, Animal; Edetic Acid; Enterocolitis, Pseudomembranous; Epithelium; Female; Guinea Pigs; Ileitis; Inflammation; Intestinal Diseases; Nitric Oxide; Nitrites; Permeability; Peroxidase; Proteins; Rabbits; Swine; Therapeutic Irrigation; Trinitrobenzenesulfonic Acid | 1993 |
Root surface etching at neutral pH promotes periodontal healing.
Topics: Acid Etching, Dental; Animals; Bicuspid; Chelating Agents; Citrates; Citric Acid; Collagen; Connective Tissue; Dental Cementum; Dentin; Disease Models, Animal; Edetic Acid; Epithelial Attachment; Gingival Recession; Macaca fascicularis; Molar; Necrosis; Periodontal Diseases; Periodontal Ligament; Periodontal Pocket; Tooth Root; Wound Healing | 1996 |
Hysteresis of the PTH-calcium curve during hypocalcemia in the dog: effect of the rate and linearity of calcium decrease and sequential episodes of hypocalcemia.
Topics: Analysis of Variance; Animals; Calcium; Calcium Chloride; Disease Models, Animal; Dogs; Edetic Acid; Hypocalcemia; Infusions, Intravenous; Parathyroid Hormone; Reproducibility of Results | 1996 |
The effectiveness of two ciprofloxacin formulations for experimental Pseudomonas and Staphylococcus keratitis.
Topics: Animals; Anti-Infective Agents; Benzalkonium Compounds; Chelating Agents; Ciprofloxacin; Colony Count, Microbial; Cornea; Disease Models, Animal; Edetic Acid; Eye Infections, Bacterial; Keratitis; Ophthalmic Solutions; Preservatives, Pharmaceutical; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Staphylococcal Infections; Staphylococcus aureus | 1996 |
Exudative and absorptive permeability in different phases of an experimental colitis condition.
Topics: Acetic Acid; Animals; Cell Membrane Permeability; Chromium Radioisotopes; Colitis; Disease Models, Animal; Edetic Acid; Exudates and Transudates; Inflammatory Bowel Diseases; Intestinal Absorption; Male; Peroxidase; Rats; Rats, Sprague-Dawley; Serum Albumin, Radio-Iodinated | 1996 |
Tissue distribution and general safety of MnDPDP in male beagle dogs, with or without total common bile duct obstruction.
Topics: Animals; Cholestasis, Extrahepatic; Common Bile Duct; Contrast Media; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Edetic Acid; Ligation; Magnetic Resonance Imaging; Male; Manganese; Prognosis; Pyridoxal Phosphate; Safety; Tissue Distribution | 1997 |
Cardiovascular effects of MnDPDP and MnCl2 in dogs with acute ischaemic heart failure.
Topics: Acute Disease; Animals; Cardiovascular System; Chlorides; Contrast Media; Depression, Chemical; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Edetic Acid; Female; Heart Failure; Hemodynamics; Male; Manganese; Manganese Compounds; Myocardial Ischemia; Pyridoxal Phosphate; Time Factors | 1997 |
Mast cell hyperplasia and increased macromolecular uptake in an animal model of giardiasis.
Topics: Animals; Biological Transport; Cell Count; Chelating Agents; Chromium Radioisotopes; Connective Tissue; Disease Models, Animal; Edetic Acid; Female; Gerbillinae; Giardiasis; Hyperplasia; Intestinal Mucosa; Jejunum; Mast Cells; Permeability; Serum Albumin, Bovine; Specific Pathogen-Free Organisms | 1997 |
Effect of manganese dipyridoxal diphosphate on liver magnetic resonance imaging and serum bilirubin in rats with removable biliary obstruction.
Topics: Animals; Bilirubin; Cholestasis; Contrast Media; Disease Models, Animal; Edetic Acid; Liver; Magnetic Resonance Imaging; Male; Pyridoxal Phosphate; Rats; Rats, Wistar; Statistics, Nonparametric | 1995 |
Disruption of intestinal barrier function associated with experimental colitis: possible role of mast cells.
Topics: Animals; Biomarkers; Body Water; Chromium Radioisotopes; Chymases; Colitis; Colon; Dexamethasone; Disease Models, Animal; Edetic Acid; Granulocytes; Intestinal Absorption; Male; Mast Cells; Peroxidase; Rats; Rats, Sprague-Dawley; Serine Endopeptidases; Thioxanthenes; Trinitrobenzenesulfonic Acid; Xanthones | 1998 |
Generation of nitric oxide from streptozotocin (STZ) in the presence of copper(II) plus ascorbate: implication for the development of STZ-induced diabetes.
Topics: Animals; Ascorbic Acid; Chelating Agents; Copper; Diabetes Mellitus, Experimental; Disease Models, Animal; Edetic Acid; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hemin; Hypoglycemic Agents; Islets of Langerhans; Niacinamide; Nitric Oxide; Phenanthrolines; Rats; Spectrophotometry; Streptozocin | 1998 |
High extracellular K+ during hypoxic preconditioning episodes attenuates the post-ischemic contractile and ionic benefits of preconditioning.
Topics: Animals; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Edetic Acid; Hypoxia; Ischemia; Ischemic Preconditioning, Myocardial; Lidocaine; Male; Perfusion; Potassium; Rats; Rats, Wistar; Reperfusion; Sarcolemma; Time Factors; Ventricular Pressure | 1999 |
Effect of hypocalcaemia on glucose metabolism in hyperketonaemic piglets.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Calcitriol; Calcium; Disease Models, Animal; Edetic Acid; Glucose; Hypocalcemia; Ketone Bodies; Swine | 1999 |
Hemoglobin toxicity in experimental bacterial peritonitis is due to production of reactive oxygen species.
Topics: Animals; Chelating Agents; Cyclic N-Oxides; Deferoxamine; Disease Models, Animal; Edetic Acid; Escherichia coli Infections; Hemin; Hemoglobins; Hydrogen Peroxide; Macrophages, Peritoneal; Male; Oxidative Stress; Pentetic Acid; Peritonitis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Superoxides | 1999 |
Plasma exudation, hyperaemia, and epithelial permeability in rats with oxazolone-induced colitis: modulatory effects of budesonide.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Budesonide; Colitis; Colon; Disease Models, Animal; Edetic Acid; Endothelium; Epithelium; Female; Glucocorticoids; Humans; Intestine, Small; Oxazolone; Permeability; Rats | 2000 |
Chelation therapy in the JCR:LA-cp rat: experimental assessment of a putative antiatherosclerotic treatment.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Bone and Bones; Calcium; Chelation Therapy; Complementary Therapies; Disease Models, Animal; Edetic Acid; Endothelium, Vascular; Insulin Resistance; Lipids; Macrophages; Magnesium; Male; Microscopy, Electron, Scanning; Obesity; Prospective Studies; Rats; Rats, Mutant Strains; Triglycerides | 2000 |
Normal and infarcted myocardium: differentiation with cellular uptake of manganese at MR imaging in a rat model.
Topics: Analysis of Variance; Animals; Contrast Media; Coronary Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Echo-Planar Imaging; Edetic Acid; Female; Follow-Up Studies; Magnetic Resonance Imaging; Manganese; Metabolic Clearance Rate; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley | 2000 |
Antioxidant effects of alpha tocopherol, ascorbic acid and L-methionine on lead induced oxidative stress to the liver, kidney and brain in rats.
Topics: Animals; Antioxidants; Ascorbic Acid; Brain; Chelating Agents; Disease Models, Animal; Edetic Acid; Kidney; Lead; Lipid Peroxides; Liver; Methionine; Organ Size; Oxidative Stress; Rats; Vitamin E | 2001 |
Refinement of an orthotopic lung cancer model in the nude rat.
Topics: Animals; Carcinoma; Disease Models, Animal; Edetic Acid; Female; Humans; Lung Neoplasms; Male; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Pancreatic Elastase; Rats; Rats, Nude; Time Factors; Transplantation, Heterologous; Tumor Cells, Cultured; Whole-Body Irradiation | 2001 |
Characterisation, cloning and sequencing of a conformation-dependent monoclonal antibody to the alphaIIbbeta3 integrin: interest for use in thrombus detection.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Affinity; Antibody Specificity; Binding Sites; Cloning, Molecular; Disease Models, Animal; Edetic Acid; Immunoconjugates; Iodine Radioisotopes; Male; Molecular Sequence Data; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Conformation; Rabbits; Radionuclide Imaging; Sequence Analysis; Thrombin; Thrombosis | 2001 |
Cardioprotective effects of the MR contrast agent MnDPDP and its metabolite MnPLED upon reperfusion of the ischemic porcine myocardium.
Topics: Animals; Blood Pressure; Cardiotonic Agents; Contrast Media; Coronary Circulation; Disease Models, Animal; Edetic Acid; Female; Magnetic Resonance Imaging; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Pyridoxal Phosphate; Swine | 2001 |
Efficacy of minocycline and EDTA lock solution in preventing catheter-related bacteremia, septic phlebitis, and endocarditis in rabbits.
Topics: Animals; Anti-Bacterial Agents; Bacteremia; Catheterization; Disease Models, Animal; Edetic Acid; Endocarditis; Male; Minocycline; Phlebitis; Prosthesis-Related Infections; Rabbits | 2002 |
HBED ligand: preclinical studies of a potential alternative to deferoxamine for treatment of chronic iron overload and acute iron poisoning.
Topics: Acute Disease; Animals; Blood Pressure; Cebus; Chronic Disease; Deferoxamine; Disease Models, Animal; Dogs; Drug Administration Routes; Drug Evaluation, Preclinical; Edetic Acid; Heart Rate; Iron; Iron Chelating Agents; Iron Overload; Male; Poisoning; Rats; Rats, Sprague-Dawley; Therapeutic Equivalency | 2002 |
Experimental lead nephropathy: treatment with calcium disodium ethylenediaminetetraacetate.
Topics: Animals; Arteries; Cell Nucleus; Chelating Agents; Creatinine; Disease Models, Animal; Edetic Acid; Fibrosis; Hypertrophy; Inclusion Bodies; Kidney Diseases; Kidney Tubules, Proximal; Lead Poisoning; Lymphocytes; Male; Microvilli; Muscle, Smooth, Vascular; Porphobilinogen Synthase; Rats; Rats, Wistar; Vacuoles | 2002 |
Quantitative approaches to the assessment of cell-mediated immune responses to solid tumor allografts.
Topics: Animals; Cytotoxicity, Immunologic; Disease Models, Animal; Edetic Acid; Immunity, Cellular; Mast-Cell Sarcoma; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Transplantation, Homologous | 1978 |
Fibrillar bodies in hepatocyte nuclei during the course of the toxic hepatitis produced by frog virus 3 in mice.
Topics: Animals; Anura; Cell Nucleus; Chemical and Drug Induced Liver Injury; Disease Models, Animal; DNA Viruses; Edetic Acid; Histocytochemistry; Inclusion Bodies; Liver; Mice; Mice, Inbred Strains; Microscopy, Electron; Pronase; Proteins; Ribonucleases | 1975 |
Comparative study on the composition of the organic matrix of the long bones of the "normal" rat and of the mutant Op/Orl.
Topics: Amino Acids; Animals; Bone Matrix; Chondroitin Sulfates; Disease Models, Animal; Edetic Acid; Femur; Glycosaminoglycans; Hexosamines; Hexoses; Hyaluronic Acid; Hydroxyproline; Osteopetrosis; Proteins; Rats; Rats, Inbred Strains; Sex Factors; Tibia; Urea | 1977 |
Wound cleansing by high pressure irrigation.
Topics: Animals; Antisepsis; Colloids; Decontamination; Disease Models, Animal; Edetic Acid; Flocculation; Guinea Pigs; Pressure; Rats; Saline Solution, Hypertonic; Soil; Surface-Active Agents; Therapeutic Irrigation; Wound Infection | 1975 |
Double-labeling of experimental acute myocardial infarcts with 113mIn- and 99mTc-EDTMP.
Topics: Animals; Disease Models, Animal; Dogs; Edetic Acid; Indium; Myocardial Infarction; Radioisotopes; Radionuclide Imaging; Technetium | 1976 |
Effect of drugs on infant Gunn rats under phototherapy.
Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; Benzyl Alcohols; Bilirubin; Body Weight; Cerebellum; Disease Models, Animal; Edetic Acid; Gentamicins; Humans; Infant, Newborn; Jaundice, Neonatal; Phototherapy; Purkinje Cells; Rats; Serum Albumin; Sulfonamides | 1976 |
Effects of zinc sulfate on Pseudomonas aeruginosa infections and protease in rabbit corneas.
Topics: Animals; Cysteine; Disease Models, Animal; Drug Evaluation, Preclinical; Edetic Acid; Keratitis; Peptide Hydrolases; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Sulfates; Zinc | 1976 |
Experimental pulmonary emphysema in Syrian hamsters.
Topics: Animals; Collagen; Connective Tissue; Cricetinae; Cysteine; Disease Models, Animal; Dose-Response Relationship, Drug; Edetic Acid; Papain; Pulmonary Alveoli; Pulmonary Emphysema | 1976 |
Evaluation of some lines of therapy in experimentally induced herpetic keratitis in rabbits.
Topics: Animals; Cautery; Corneal Transplantation; Cryosurgery; Debridement; Disease Models, Animal; Edetic Acid; Humans; Idoxuridine; Keratitis, Dendritic; Rabbits | 1976 |
Reactivation of latent herpes simplex virus by excimer laser photokeratectomy.
Topics: Animals; Cornea; Disease Models, Animal; Edetic Acid; Epithelium; Eye Infections, Viral; Female; Keratitis, Herpetic; Laser Therapy; Mice; Mice, Inbred Strains; Simplexvirus; Virus Activation; Virus Replication | 1992 |
Conduction of early afterdepolarizations in sheep Purkinje fibers and ventricular muscle. An in vitro arrhythmia model.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Disease Models, Animal; Edetic Acid; Heart Ventricles; In Vitro Techniques; Neural Conduction; Purkinje Fibers | 1992 |
Alterations in intestinal permeability and blood flow in a new model of mesenteric ischemia.
Topics: Animals; Cell Membrane Permeability; Disease Models, Animal; Edetic Acid; Intestinal Mucosa; Ischemia; Male; Mesentery; Microspheres; Rats; Rats, Inbred Strains; Regional Blood Flow; Reperfusion | 1992 |
Potential role of histamine monochloramine in a rabbit model of ileitis.
Topics: Acute Disease; Animals; Cell Membrane Permeability; Chloramines; Chromium Radioisotopes; Disease Models, Animal; Edetic Acid; Histamine; Ileitis; Intestinal Mucosa; Peroxidase; Rabbits | 1991 |
[Activation of lipid peroxidation in the liver mitochondria and acute toxicity of chemical compounds].
Topics: Acute Disease; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Edetic Acid; In Vitro Techniques; Lipid Peroxidation; Male; Mitochondria, Liver; Oxidative Phosphorylation; Rats; Solvents | 1991 |
Abnormal permeability precedes the development of a gluten sensitive enteropathy in Irish setter dogs.
Topics: Alkaline Phosphatase; Animals; Celiac Disease; Disease Models, Animal; Dogs; Edetic Acid; Glutens; Intestinal Absorption; Jejunum; Permeability | 1991 |
Experimental non-steroidal anti-inflammatory drug-induced enteropathy in the rat: similarities to inflammatory bowel disease and effect of thromboxane synthetase inhibitors.
Topics: Animals; Cell Membrane Permeability; Chromium Radioisotopes; Disease Models, Animal; Edetic Acid; Ileum; Imidazoles; Indomethacin; Inflammatory Bowel Diseases; Jejunum; Male; Peroxidase; Prednisolone; Rats; Rats, Inbred Strains; Sulfasalazine; Tetracycline; Thromboxane-A Synthase | 1990 |
A comparison between the main clinical signs of milk fever in cows with those of hypocalcaemia induced by Na2EDTA solution.
Topics: Animals; Cattle; Cattle Diseases; Disease Models, Animal; Edetic Acid; Erythrocytes; Female; Hypocalcemia; Parturient Paresis; Potassium; Pregnancy | 1990 |
Drug-induced inhibition of proteoglycanase activity in the Hulth-Telhag model.
Topics: Animals; Disease Models, Animal; Edetic Acid; Endopeptidases; Enzyme Inhibitors; Injections, Intra-Articular; Knee Joint; Metalloendopeptidases; Microscopy, Electron; Osteoarthritis; Protease Inhibitors; Rabbits | 1989 |
Degradative enzyme systems in osteoarthritic cartilage.
Topics: Acid Phosphatase; Animals; Cartilage, Articular; Cytidine; Disease Models, Animal; Edetic Acid; Egtazic Acid; Endopeptidases; Glycosaminoglycans; Humans; Hydrogen-Ion Concentration; Metalloendopeptidases; Microbial Collagenase; Osteoarthritis; Rabbits; Thymidine | 1985 |
Experimental calcification of the myocardium. Ultrastructural and histochemical investigations.
Topics: Animals; Calcinosis; Cardiomyopathies; Dihydrotachysterol; Disease Models, Animal; Edetic Acid; Female; Hypercalcemia; Microscopy, Electron; Mitochondria, Muscle; Myocardium; Rats | 1973 |
Enhancement of ampicillin efficacy by peroral levodopa in rat pyelonephritis.
Topics: Administration, Oral; Ampicillin; Animals; Catechols; Cephalothin; Dihydroxyphenylalanine; Disease Models, Animal; Drug Synergism; Edetic Acid; Escherichia coli Infections; Nitrofurantoin; Phenylacetates; Pyelonephritis; Rats; Time Factors | 1972 |
Combinations of edetic acid and antibiotics in the treatment of rat burns infected with a resistant strain of Pseudomonas aeruginosa.
Topics: Ampicillin; Animals; Burns; Disease Models, Animal; Edetic Acid; Mice; Microbial Sensitivity Tests; Penicillin Resistance; Pseudomonas aeruginosa; Pseudomonas Infections; Tetracycline; Wound Infection | 1973 |
The effect of tobramycin on Pseudomonas keratitis.
Topics: Amino Sugars; Animals; Anti-Bacterial Agents; Cornea; Disease Models, Animal; Edetic Acid; El Salvador; Exudates and Transudates; Gentamicins; Glycosides; Injections; Keratitis; Male; Microbial Sensitivity Tests; Ophthalmic Solutions; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits | 1973 |
[Origin and reversibility of hydronephrosis in multirenicular kidneys. II. Function studies and radioisotope clearance in young midget pigs].
Topics: Animals; Chromium Radioisotopes; Disease Models, Animal; Edetic Acid; Female; Glomerular Filtration Rate; Hydronephrosis; Iodine Radioisotopes; Iodohippuric Acid; Ligation; Nephrectomy; Regeneration; Species Specificity; Swine; Time Factors; Ureter | 1974 |
Collagenase inhibitors in Pseudomonas keratitis. Adjuncts to antibiotic therapy in rabbits.
Topics: Animals; Corneal Ulcer; Cysteine; Disease Models, Animal; Drug Therapy, Combination; Edetic Acid; Evaluation Studies as Topic; Female; Microbial Collagenase; Ophthalmic Solutions; Polymyxins; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Sodium Chloride; Sulfates; Time Factors | 1974 |
Role of antibody and complement in the immune clearance and destruction of erythrocytes. II. Molecular nature of IgG and IgM complement-fixing sites and effects of their interaction with serum.
Topics: Animals; Antibody Specificity; Antigen-Antibody Reactions; Binding Sites; Cell Survival; Chromium Isotopes; Complement Fixation Tests; Complement System Proteins; Coombs Test; Disease Models, Animal; Edetic Acid; Erythrocytes; Guinea Pigs; Hemagglutination Tests; Hemolysis; Immunity, Cellular; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Iodine Isotopes; Liver; Rabbits; Time Factors; Venoms | 1972 |
The first phase of pseudomonadal pneumonia influenced by the administration of ampicillin + EDTA in vivo.
Topics: Ampicillin; Animals; Disease Models, Animal; Drug Synergism; Edetic Acid; Leukocytosis; Phagocytosis; Pneumonia; Pseudomonas aeruginosa; Pseudomonas Infections; Pulmonary Alveoli; Rabbits | 1970 |
Orally administered solasodine, a steroidal glycoalkaloid, suppresses ovalbumin-induced exaggerated Th2-immune response in rat model of bronchial asthma.
Topics: Allergens; Aluminum Hydroxide; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Dexamethasone; Disease Models, Animal; Histamine; Humans; Immunity; Immunoglobulin E; Interleukin-4; Interleukin-5; Lung; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Nitric Oxide; Nitrites; Ovalbumin; Rats; Solanaceous Alkaloids; Tumor Necrosis Factor-alpha | 2022 |
Effect of ethanolic extract of Solanum virginianum Linn. on neuropathic pain using chronic constriction injury rat model and molecular docking studies.
Topics: Analgesics; Animals; Behavior, Animal; Binding Sites; Binding, Competitive; Calcium Channels, N-Type; Disease Models, Animal; Ethanol; Female; Hyperalgesia; Male; Molecular Docking Simulation; Neuralgia; Pain Threshold; Plant Extracts; Protein Binding; Rats, Wistar; Sciatic Neuropathy; Solanaceous Alkaloids; Solanum; Solvents | 2020 |
In silico and in vivo characterization of cabralealactone, solasodin and salvadorin in a rat model: potential anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Carbon Tetrachloride; Coumarins; Cyclooxygenase 2; Disease Models, Animal; DNA; Injections, Intraperitoneal; Lactones; Liver; Molecular Docking Simulation; Naphthalenes; Oxidative Stress; Rats; Solanaceous Alkaloids; Tumor Necrosis Factor-alpha | 2018 |
Natural product solasodine-3-O-β-D-glucopyranoside inhibits the virulence factors of Candida albicans.
Topics: Animals; Antifungal Agents; Biofilms; Biological Products; Caenorhabditis elegans; Candida albicans; Cyclic AMP; Disease Models, Animal; Glycosides; Hyphae; Microbial Viability; Signal Transduction; Solanaceous Alkaloids; Solanum; Survival Analysis; Virulence Factors | 2015 |
Anticonvulsant activity of solasodine isolated from Solanum sisymbriifolium fruits in rodents.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fruit; Hypnotics and Sedatives; Injections, Intraperitoneal; Male; Mice; Rats; Rats, Wistar; Seizures; Solanaceous Alkaloids; Solanum | 2011 |