edetic acid has been researched along with Alzheimer Disease in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (14.81) | 18.7374 |
| 1990's | 5 (18.52) | 18.2507 |
| 2000's | 6 (22.22) | 29.6817 |
| 2010's | 8 (29.63) | 24.3611 |
| 2020's | 4 (14.81) | 2.80 |
| Authors | Studies |
|---|---|
| Kong, LY; Li, SY; Wang, XB | 1 |
| Manral, A; Meena, P; Saini, V; Tiwari, M | 1 |
| Cai, P; Kong, LY; Liu, QH; Wang, XB; Wang, ZM; Wu, JJ; Xu, DQ; Yang, XL | 1 |
| Edraki, N; Firuzi, O; Iraji, A; Khoshneviszadeh, M; Mahdavi, M; Miri, R; Nadri, H; Tavakkoli, M | 1 |
| Liu, P; Liu, ZP; Shi, XL; Wu, JD | 1 |
| Andrisano, V; Arce, EM; Barenys, M; Bartolini, M; Bolognesi, ML; Brea, J; De Simone, A; Decker, M; Ginex, T; Gómez-Catalán, J; Griñán-Ferré, C; Loza, MI; Luque, FJ; Martínez, N; Mattellone, A; Muñoz-Torrero, D; Naldi, M; Pallàs, M; Pérez, B; Pont, C; Sabate, R; Scheiner, M; Soriano-Fernández, Y | 1 |
| Ding, X; Jiang, L; Lei, P; Li, T; Wang, W; Yang, X | 1 |
| Han, SW; Jeong, HB; Kim, HR; Kim, S; Park, YH; Pyun, JM; Ryoo, N; Shin, HW; Youn, YC | 1 |
| Bittner, T; Gürsel, SÜ; Jethwa, A; Kurz, C; Perneczky, R; Schrurs, I; Stöckl, L; Suridjan, I | 1 |
| Hara, M; Mitsuda, Y; Nishiyama, Y; Paul, S; Planque, SA; Taguchi, H | 1 |
| Adlard, PA; Bush, AI; Finkelstein, DI; Fowler, CJ; Gupta, VB; Martins, IJ; Martins, RN; Xu, H | 1 |
| Fagan, AM; Grodstein, F; Hyman, BT; Irizarry, MC; Mehta, PD; Okereke, OI; Qiu, WQ; Selkoe, DJ; Sun, X; Xia, W | 1 |
| Myint, KT; Nakamura, T; Oda, Y | 1 |
| Boutaud, O; Caprioli, RM; Chaurand, P; Montine, TJ; Oates, JA; Ou, JJ | 1 |
| Berthon, G; Collingwood, J; Exley, C; House, E; Khan, A; Korchazkina, O | 1 |
| Hazell, AS; Kennedy, G; Norenberg, MD; Normandin, L; Yi, JH | 1 |
| Forssmann, WG; John, H; Schulz, S | 1 |
| Abbott, LB; Lott, JA | 1 |
| Beyreuther, K; Bush, AI; d Paradis, M; Gusella, JF; Masters, CL; Multhaup, G; Pettingell, WH; Tanzi, RE; Vonsattel, JP | 1 |
| Holopainen, JM; Kinnunen, PK; Lehtonen, JY | 1 |
| Haley, BE; Pendergrass, JC | 1 |
| Abraham, CR; Billingslea, A; Cribbs, DH; Davies, TA; Eisenhauer, P; Fine, RE; Long, HJ; Marshall, DC; Otto, K; Simons, ER; Tibbles, H; Wells, J | 1 |
| Ladner, CJ; Lee, JM | 1 |
| Hoyer, S; Yun, SW | 1 |
| Rai, GS | 1 |
| Carson, RE; Rapoport, SI; Schlageter, NL | 1 |
| Bagne, CA; Cardelli, MB; Pomara, N; Russell, M | 1 |
1 review(s) available for edetic acid and Alzheimer Disease
| Article | Year |
|---|---|
Inhibition of brain tubulin-guanosine 5'-triphosphate interactions by mercury: similarity to observations in Alzheimer's diseased brain.
Topics: Administration, Inhalation; Alzheimer Disease; Animals; Binding Sites; Brain; Chelating Agents; Edetic Acid; Egtazic Acid; Glutamic Acid; Guanosine Triphosphate; Humans; Isotope Labeling; Mercury; Microtubules; Nucleotides; Rats; Tubulin | 1997 |
26 other study(ies) available for edetic acid and Alzheimer Disease
| Article | Year |
|---|---|
Design, synthesis and biological evaluation of imine resveratrol derivatives as multi-targeted agents against Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Cell Line, Tumor; Copper; Humans; Neuroprotective Agents; Reactive Oxygen Species; Resveratrol; Stilbenes | 2014 |
Multifunctional novel Diallyl disulfide (DADS) derivatives with β-amyloid-reducing, cholinergic, antioxidant and metal chelating properties for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Allyl Compounds; Alzheimer Disease; Amyloid beta-Peptides; Anhydrides; Antioxidants; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Chelating Agents; Cholinesterase Inhibitors; Copper; Disulfides; Humans; Molecular Docking Simulation; Structure-Activity Relationship | 2015 |
Rational modification of donepezil as multifunctional acetylcholinesterase inhibitors for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cell Survival; Cholinesterase Inhibitors; Copper; Donepezil; Drug Design; Humans; Indans; Kinetics; Liver; Mice; Models, Molecular; Peptide Fragments; Piperidines; Protein Aggregates; Protein Conformation | 2016 |
Multifunctional iminochromene-2H-carboxamide derivatives containing different aminomethylene triazole with BACE1 inhibitory, neuroprotective and metal chelating properties targeting Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Benzopyrans; Cell Proliferation; Chelating Agents; Dose-Response Relationship, Drug; Humans; Molecular Structure; Neuroprotective Agents; PC12 Cells; Rats; Structure-Activity Relationship; Triazoles | 2017 |
Synthesis and evaluation of novel GSK-3β inhibitors as multifunctional agents against Alzheimer's disease.
Topics: Alzheimer Disease; Amides; Amines; Animals; Antioxidants; Blood-Brain Barrier; Cell Line; Chelating Agents; Drug Design; Glycogen Synthase Kinase 3 beta; Humans; PC12 Cells; Protein Aggregation, Pathological; Protein Kinase Inhibitors; Rats; Structure-Activity Relationship; tau Proteins | 2019 |
From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects.
Topics: Alzheimer Disease; Aminoquinolines; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Brain; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Heterocyclic Compounds, 4 or More Rings; Humans; Molecular Dynamics Simulation; Molecular Structure; Neuroprotective Agents; Recombinant Proteins; Structure-Activity Relationship; tau Proteins | 2021 |
Head-to-Head Comparison of Different Blood Collecting Tubes for Quantification of Alzheimer's Disease Biomarkers in Plasma.
Topics: Adult; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Edetic Acid; Female; Heparin; Humans; Lithium; Male; Peptide Fragments; tau Proteins; Young Adult | 2022 |
Prediction of amyloid PET positivity via machine learning algorithms trained with EDTA-based blood amyloid-β oligomerization data.
Topics: Algorithms; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Cognitive Dysfunction; Edetic Acid; Humans; Machine Learning; Positron-Emission Tomography | 2022 |
Impact of pre-analytical sample handling factors on plasma biomarkers of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Edetic Acid; Humans; Peptide Fragments; Reproducibility of Results; Specimen Handling; tau Proteins | 2023 |
Metal-dependent amyloid β-degrading catalytic antibody construct.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antibodies, Catalytic; Chelating Agents; Copper; Edetic Acid; Humans; Hydrolysis; Zinc | 2014 |
Zinc affects the proteolytic stability of Apolipoprotein E in an isoform-dependent way.
Topics: Alzheimer Disease; Apolipoproteins E; Chelating Agents; Dose-Response Relationship, Drug; Edetic Acid; Enzyme Inhibitors; Humans; Plasma; Protein Isoforms; Serine Proteases; Thrombin; Trace Elements; Zinc | 2015 |
Performance characteristics of plasma amyloid-beta 40 and 42 assays.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Anticoagulants; Biomarkers; Edetic Acid; Enzyme-Linked Immunosorbent Assay; Heparin; Humans; Peptide Fragments; Reproducibility of Results; Sensitivity and Specificity; Time Factors | 2009 |
Ethylenediaminetetraacetic acid increases identification rate of phosphoproteomics in real biological samples.
Topics: Alzheimer Disease; Animals; Brain Chemistry; Chromatography, Affinity; Disease Models, Animal; Edetic Acid; Humans; Mass Spectrometry; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphoproteins; Phosphoric Acids; Proteomics; Titanium | 2010 |
Prostaglandin H2 (PGH2) accelerates formation of amyloid beta1-42 oligomers.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Chelating Agents; Dimerization; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Macromolecular Substances; Microscopy, Electron; Peptide Fragments; Polymers; Prostaglandin H2; Prostaglandins E; Prostaglandins H; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2002 |
Aluminium, iron, zinc and copper influence the in vitro formation of amyloid fibrils of Abeta42 in a manner which may have consequences for metal chelation therapy in Alzheimer's disease.
Topics: Aluminum; Alzheimer Disease; Amyloid beta-Peptides; Brain; Chelation Therapy; Chromatography, High Pressure Liquid; Copper; Edetic Acid; Humans; In Vitro Techniques; Iron; Peptide Fragments; Zinc | 2004 |
Alzheimer type II astrocytic changes following sub-acute exposure to manganese and its prevention by antioxidant treatment.
Topics: Acetylcysteine; Alzheimer Disease; Analysis of Variance; Animals; Antioxidants; Astrocytes; Cerebral Cortex; Chelating Agents; Disease Models, Animal; Drug Interactions; Edetic Acid; Male; Manganese; Rats; Rats, Sprague-Dawley; Time Factors | 2006 |
Validated multi-component CZE-UV procedure for the quantification of human hemorphin LVV-H7 in plasma stability studies.
Topics: Alzheimer Disease; CD13 Antigens; Edetic Acid; Electrophoresis, Capillary; Hemoglobins; Humans; Learning; Peptide Fragments; Reproducibility of Results; Species Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Time Factors | 2006 |
Reactivation of serum creatine kinase isoenzyme BB in patients with malignancies.
Topics: Adenylate Kinase; Alzheimer Disease; Blood Protein Electrophoresis; Chelating Agents; Creatine Kinase; Edetic Acid; Electrophoresis, Agar Gel; Enzyme Reactivators; Humans; Isoenzymes; Mercaptoethanol; Neoplasms; Sulfhydryl Compounds | 1984 |
Rapid induction of Alzheimer A beta amyloid formation by zinc.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Edetic Acid; Humans; Kinetics; Mice; Peptide Fragments; Rats; Solubility; Zinc | 1994 |
Activation of phospholipase A2 by amyloid beta-peptides in vitro.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Calcium; Edetic Acid; Enzyme Activation; Humans; Hydrolysis; Kinetics; Molecular Sequence Data; Pancreas; Peptide Fragments; Phosphatidylglycerols; Phospholipases A; Phospholipases A2; Phospholipids; Swine | 1996 |
Blood brain barrier endothelial cells express candidate amyloid precursor protein-cleaving secretases.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Antibody Specificity; Aspartic Acid Endopeptidases; Blood Platelets; Blood-Brain Barrier; Edetic Acid; Endopeptidases; Endothelium, Vascular; Humans; Hydroxamic Acids; Immunohistochemistry; Metalloendopeptidases; Oligopeptides | 1998 |
Reduced high-affinity agonist binding at the M(1) muscarinic receptor in Alzheimer's disease brain: differential sensitivity to agonists and divalent cations.
Topics: Acetylcholine; Aged; Alzheimer Disease; Brain; Carbachol; Cations, Divalent; Chlorides; Edetic Acid; Female; Guanylyl Imidodiphosphate; Humans; Kinetics; Magnesium Chloride; Male; Manganese Compounds; Muscarinic Agonists; Oxotremorine; Pirenzepine; Receptor, Muscarinic M1; Receptors, Muscarinic; Reference Values | 1999 |
Effects of low-level lead on glycolytic enzymes and pyruvate dehydrogenase of rat brain in vitro: relevance to sporadic Alzheimer's disease?
Topics: Adenosine Triphosphate; Alzheimer Disease; Animals; Brain; Chelating Agents; Cysteine; Dithiothreitol; Edetic Acid; Enzyme Activation; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Hexokinase; In Vitro Techniques; Lead; Male; Organometallic Compounds; Pyruvate Dehydrogenase Complex; Pyruvate Kinase; Rats; Rats, Wistar | 2000 |
Chelation therapy in dementia.
Topics: Alzheimer Disease; Edetic Acid; Humans; Zinc | 1986 |
Examination of blood-brain barrier permeability in dementia of the Alzheimer type with [68Ga]EDTA and positron emission tomography.
Topics: Aged; Alzheimer Disease; Blood-Brain Barrier; Edetic Acid; Gallium Radioisotopes; Humans; Male; Middle Aged; Permeability; Tomography, Emission-Computed | 1987 |
Chelation therapy. Unproved modality in the treatment of Alzheimer-type dementia.
Topics: Aged; Alzheimer Disease; Edetic Acid; Female; Humans; Infusions, Parenteral; Metals; Quackery | 1985 |