Page last updated: 2024-08-17

edetic acid and Acute Liver Injury, Drug-Induced

edetic acid has been researched along with Acute Liver Injury, Drug-Induced in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199015 (60.00)18.7374
1990's5 (20.00)18.2507
2000's0 (0.00)29.6817
2010's4 (16.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Akakpo, JY; Jaeschke, H; Ramachandran, A1
Dear, J1
Black, P; Dear, JW; Gallagher, B; Grahamslaw, J; Henriksen, D; Lee, RJ; Morrison, EE; O'Brien, R; Oatey, K; Oosthuyzen, W; Weir, CJ1
DIBELLA, S; PICHIERRI, U; RICHETTA, G1
EYBL, V; MERTL, F; SYKORA, J1
COVEY, TJ1
VILLELA, GG1
CARROLL, R; TAPP, E1
Wedeen, RP1
Brent, J; Kulig, K; McKinney, PE1
Das Gupta, S; Flora, SJ; Mathur, R; Mathur, S1
D'Alteroche, L; Dorval, ED; Fimbel, B; Metman, EH; Picon, L; Raabe, JJ1
Ahmed, S; Athar, M; Rahman, A; Saleem, M; Sultana, S1
Bingen, A; Kirn, A1
Engström, B; Nordberg, GF1
Chandra, SV; Husain, R; Seth, PK; Singh, J; Tandon, SK1
Chamorovskaia, LT; MItrokhin, NM; Zhigacheva, IV1
Carter, EA; Matkin, C; Ratner, AV; Simpson, BB; Young, SW1
Glende, EA; Recknagel, RO1
Gedigk, P; Giersberg, O; Wessel, W1
Johnson, RB1
Plaa, GL; Rice, AJ1
Howell, JM; Isael, J; Treeby, PJ1

Reviews

4 review(s) available for edetic acid and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Novel strategies for the treatment of acetaminophen hepatotoxicity.
    Expert opinion on drug metabolism & toxicology, 2020, Volume: 16, Issue:11

    Topics: Acetaminophen; Acetylcysteine; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Drug Overdose; Edetic Acid; Fomepizole; Hepatocytes; Humans; Liver Failure, Acute; Pyridoxal Phosphate

2020
BIOCHEMICAL ASPECTS OF CARBON TETRACHLORIDE POISONING.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Alkaline Phosphatase; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Edetic Acid; Fatty Acids; Fatty Liver; Glycerides; Hepatitis; Isocitrate Dehydrogenase; Liver Regeneration; Malate Dehydrogenase; Mitochondria; NAD; Necrosis; Nucleotidases; Oxidoreductases; Phospholipids; Potassium; Rats; Research; RNA; Toxicology

1964
Occupational renal disease.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1984, Volume: 3, Issue:4

    Topics: Arsenic Poisoning; Berylliosis; Cadmium Poisoning; Chemical and Drug Induced Liver Injury; Edetic Acid; Glomerular Filtration Rate; Humans; Kidney Diseases; Lead Poisoning; Mercury Poisoning; Occupational Diseases; Silicosis; Solvents

1984

Trials

2 trial(s) available for edetic acid and Acute Liver Injury, Drug-Induced

ArticleYear
Randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with the 12-h regimen of N-acetylcysteine for paracetamol overdose-the PP100-01 for Overdose of Paracetamol (POP) trial: study protocol for a randomi
    Trials, 2019, Jan-08, Volume: 20, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Chemical and Drug Induced Liver Injury; Clinical Trials Data Monitoring Committees; Clinical Trials, Phase I as Topic; Data Interpretation, Statistical; Drug Overdose; Drug Therapy, Combination; Edetic Acid; Female; Humans; Male; Outcome Assessment, Health Care; Pyridoxal Phosphate; Randomized Controlled Trials as Topic; Research Design

2019
Principal results of a randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with a 12 h regimen of N-acetylcysteine for paracetamol overdose (POP trial).
    EBioMedicine, 2019, Volume: 46

    Topics: Acetaminophen; Acetylcysteine; Adult; Biomarkers; Chemical and Drug Induced Liver Injury; Drug Interactions; Drug Overdose; Edetic Acid; Female; Humans; Male; Protective Agents; Pyridoxal Phosphate; Time Factors; Young Adult

2019

Other Studies

19 other study(ies) available for edetic acid and Acute Liver Injury, Drug-Induced

ArticleYear
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests

2011
ON PATHOLOGICAL OCCURRENCE OF GLUCOSE-6-PHOSPHATASE IN BLOOD SERUM.
    Clinica chimica acta; international journal of clinical chemistry, 1963, Volume: 8

    Topics: Alkaline Phosphatase; Blood Chemical Analysis; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Clinical Enzyme Tests; Cyanides; Edetic Acid; Glucose-6-Phosphatase; Glycerophosphates; Hepatitis; Rats; Research; Serum; Toxicology

1963
[EFFECT OF CALCIUM COMPLEXES OF AMINOPOLYCARBOXYLIC ACIDS ON ACUTE EXPERIMENTAL CADMIUM POISONING].
    Pracovni lekarstvi, 1963, Volume: 15

    Topics: Animals; Cadmium; Cadmium Poisoning; Calcium; Chelating Agents; Chemical and Drug Induced Liver Injury; Edetic Acid; Gastrointestinal Tract; Hepatitis; Humans; Kidney; Male; Mice; Pharmacology; Rats; Research; Spleen; Testis; Toxicology

1963
FERROUS SULFATE POISONING: A REVIEW, CASE SUMMARIES, AND THERAPEUTIC REGIMEN.
    The Journal of pediatrics, 1964, Volume: 64

    Topics: Blood Chemical Analysis; Chemical and Drug Induced Liver Injury; Dialysis; Edetic Acid; Ferrous Compounds; Heavy Metal Poisoning; Hepatitis; Hepatitis A; Infant; Iron; Metals, Heavy; Poisoning; Renal Dialysis; Sulfates; Toxicology; Urine

1964
TETRACYCLINE ACCUMULATION IN TOXIC LIVER DAMAGE.
    The Journal of pathology and bacteriology, 1965, Volume: 89

    Topics: Amides; Calcium; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Edetic Acid; Fluorescence; Formates; Hepatitis; Hepatitis A; Metabolism; Necrosis; Pathology; Pharmacology; Promethazine; Rats; Research; Sulfhydryl Compounds; Tetracycline; Toxicology

1965
Acute zinc chloride ingestion in a child: local and systemic effects.
    Annals of emergency medicine, 1994, Volume: 23, Issue:6

    Topics: Acidosis; Acute Disease; Ammonium Chloride; Amylases; Burns, Chemical; Chemical and Drug Induced Liver Injury; Chlorides; Dimercaprol; Drug Therapy, Combination; Edetic Acid; Emergency Service, Hospital; Humans; Hypertension; Infant; Male; Poisoning; Pyloric Antrum; Sleep Stages; Zinc Compounds

1994
Mobilization and distribution of beryllium over the course of chelation therapy with some polyaminocarboxylic acids in the rat.
    Human & experimental toxicology, 1993, Volume: 12, Issue:1

    Topics: Animals; Berylliosis; Beryllium; Chelating Agents; Chelation Therapy; Chemical and Drug Induced Liver Injury; Edetic Acid; Kidney Diseases; Liver Diseases; Male; Pentetic Acid; Rats; Splenic Diseases

1993
[Acute hepatitis caused by exposure to lead].
    Gastroenterologie clinique et biologique, 1995, Volume: 19, Issue:11

    Topics: Acute Disease; Adult; Antidotes; Chemical and Drug Induced Liver Injury; Edetic Acid; Humans; Lead Poisoning; Male; Occupational Diseases

1995
Ellagic acid ameliorates nickel induced biochemical alterations: diminution of oxidative stress.
    Human & experimental toxicology, 1999, Volume: 18, Issue:11

    Topics: Animals; Biomarkers; Chelating Agents; Chemical and Drug Induced Liver Injury; Edetic Acid; Ellagic Acid; Environmental Pollutants; Female; Kidney; Kidney Diseases; Liver; Liver Diseases; Nickel; Oxidative Stress; Rats; Rats, Wistar

1999
Fibrillar bodies in hepatocyte nuclei during the course of the toxic hepatitis produced by frog virus 3 in mice.
    Journal of ultrastructure research, 1975, Volume: 50, Issue:2

    Topics: Animals; Anura; Cell Nucleus; Chemical and Drug Induced Liver Injury; Disease Models, Animal; DNA Viruses; Edetic Acid; Histocytochemistry; Inclusion Bodies; Liver; Mice; Mice, Inbred Strains; Microscopy, Electron; Pronase; Proteins; Ribonucleases

1975
Effects of detergent formula chelating agents on the metabolism and toxicity of cadmium in mice.
    Acta pharmacologica et toxicologica, 1978, Volume: 43, Issue:5

    Topics: Animals; Cadmium; Cadmium Poisoning; Chelating Agents; Chemical and Drug Induced Liver Injury; Detergents; Drug Synergism; Edetic Acid; Female; Liver; Male; Mice; Necrosis; Nitrilotriacetic Acid; Phosphates; Time Factors; Tissue Distribution

1978
Chelation in metal intoxication. I. In vivo effect of chelating agents on liver and testis of manganese administered rats.
    Environmental research, 1975, Volume: 9, Issue:1

    Topics: Aminosalicylic Acids; Animals; Chelating Agents; Chemical and Drug Induced Liver Injury; Edetic Acid; Injections, Intraperitoneal; Liver; Male; Manganese; Manganese Poisoning; Nitrilotriacetic Acid; Pentetic Acid; Proteins; Rats; Succinate Dehydrogenase; Testis

1975
[Activation of lipid peroxidation in the liver mitochondria and acute toxicity of chemical compounds].
    Gigiena i sanitariia, 1991, Issue:1

    Topics: Acute Disease; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Edetic Acid; In Vitro Techniques; Lipid Peroxidation; Male; Mitochondria, Liver; Oxidative Phosphorylation; Rats; Solvents

1991
MRI measurement of hepatocyte toxicity using the new MRI contrast agent manganese dipyridoxal diphosphate, a manganese/pyridoxal 5-phosphate chelate.
    Magnetic resonance in medicine, 1989, Volume: 10, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Contrast Media; Edetic Acid; Ethanol; Galactosamine; Liver; Liver Diseases; Magnetic Resonance Imaging; Manganese; Pyridoxal Phosphate; Rabbits; Time Factors

1989
Biochemical basis for the in vitro pro-oxidant action of carbon tetrachloride.
    Experimental and molecular pathology, 1969, Volume: 11, Issue:2

    Topics: Aldehydes; Animals; Antimetabolites; Benzene; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cytochromes; Edetic Acid; Electron Transport; Ferricyanides; Glutathione; Lipid Metabolism; Male; Malonates; Methane; Microsomes, Liver; NADP; Oxidation-Reduction; Rats

1969
[Electron microscopic and morphometric studies on rabbit liver after intravenous injection of organically bound copper].
    Virchows Archiv fur pathologische Anatomie und Physiologie und fur klinische Medizin, 1966, Jan-28, Volume: 340, Issue:3

    Topics: Animals; Chemical and Drug Induced Liver Injury; Copper; Cytoplasm; Edetic Acid; Liver; Microscopy, Electron; Mitochondria, Liver; Phagocytosis; Pinocytosis; Rabbits

1966
A new fluorometric method for the estimation or detection of total and fractionated alkaline phosphatase.
    Clinical chemistry, 1969, Volume: 15, Issue:2

    Topics: Alcohols; Alkaline Phosphatase; Buffers; Chemical and Drug Induced Liver Injury; Cholestasis; Edetic Acid; Electrophoresis; Fluorometry; Glycerophosphates; Hepatomegaly; Humans; Hydrogen-Ion Concentration; Isoenzymes; Liver Diseases; Magnesium; Male; Methods; Naphthalenes; Neoplasm Metastasis; Prostatic Neoplasms; Temperature; Time Factors

1969
The role of triglyceride accumulation and of necrosis in the hemodynamic responses of the isolated perfused rat liver after administration of carbon tetrachloride.
    Toxicology and applied pharmacology, 1969, Volume: 14, Issue:1

    Topics: Acetates; Amides; Animals; Body Temperature; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Castration; Chemical and Drug Induced Liver Injury; Edetic Acid; Ethionine; Female; Hemodynamics; Hypothermia, Induced; Liver Circulation; Liver Diseases; Male; Methionine; Necrosis; Ovary; Perfusion; Promethazine; Quaternary Ammonium Compounds; Rats; Testosterone; Triglycerides

1969
Deaths in ewes following the administration of copper calcium edetate for prevention of swayback.
    The Veterinary record, 1969, Aug-16, Volume: 85, Issue:7

    Topics: Animals; Chemical and Drug Induced Liver Injury; Copper; Deficiency Diseases; Demyelinating Diseases; Edetic Acid; Gastrointestinal Hemorrhage; Hemorrhage; Kidney; Liver; Sheep; Sheep Diseases; Swayback

1969