edelfosine has been researched along with MS (Multiple Sclerosis) in 3 studies
edelfosine: RN given refers to parent cpd
edelfosine : A racemate comprising equimolar amounts of (R)- and (S)-edelfosine.
1-octadecyl-2-methylglycero-3-phosphocholine : A glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Edelfosine has been proposed for the treatment of autoimmune diseases like multiple sclerosis (MS)." | 1.40 | The orally available, synthetic ether lipid edelfosine inhibits T cell proliferation and induces a type I interferon response. ( Abramowski, P; Martin, R; Otto, B, 2014) |
| "High corticosterone levels were detected during stages of acute paralysis, whereas a decrease to normal levels was noted during each recovery phase." | 1.29 | Immunoregulation and drug treatment in chronic relapsing experimental allergic encephalomyelitis in the Lewis rat. ( Borel, JF; Chabannes, D; Kovarik, J, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abramowski, P | 2 |
| Otto, B | 1 |
| Martin, R | 2 |
| Steinbach, K | 1 |
| Zander, AR | 1 |
| Kovarik, J | 1 |
| Chabannes, D | 1 |
| Borel, JF | 1 |
3 other studies available for edelfosine and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
The orally available, synthetic ether lipid edelfosine inhibits T cell proliferation and induces a type I interferon response.
Topics: Antineoplastic Agents; Biomarkers; CD4-Positive T-Lymphocytes; Cell Proliferation; Cells, Cultured; | 2014 |
Immunomodulatory effects of the ether phospholipid edelfosine in experimental autoimmune encephalomyelitis.
Topics: Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Encephalomyelitis, | 2014 |
Immunoregulation and drug treatment in chronic relapsing experimental allergic encephalomyelitis in the Lewis rat.
Topics: Animals; Autoimmune Diseases; Concanavalin A; Corticosterone; Cyclosporine; Dexamethasone; Disease M | 1995 |