Page last updated: 2024-10-21

edelfosine and Leukemia L 1210

edelfosine has been researched along with Leukemia L 1210 in 7 studies

edelfosine: RN given refers to parent cpd
edelfosine : A racemate comprising equimolar amounts of (R)- and (S)-edelfosine.
1-octadecyl-2-methylglycero-3-phosphocholine : A glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's6 (85.71)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Diomede, L1
Damia, G1
D'Incalci, M1
Imperatori, L1
Algeri, M1
Modest, EJ2
Salmona, M1
Wagner, BA3
Buettner, GR3
Burns, CP4
Kelley, EE1
Marino-Albernas, JR1
Bittman, R1
Peters, A1
Mayhew, E1
Unger, C1
Eibl, H1
Kim, DJ1
Fleer, EA1
Kötting, J1
Bartsch, HH1
Nagel, GA1
Pfizenmaier, K1

Other Studies

7 other studies available for edelfosine and Leukemia L 1210

ArticleYear
In vivo anti-tumor activity of synthetic ether lipids is not enhanced by pharmacological modulation of tumor lipid composition.
    International journal of cancer, 1994, Nov-15, Volume: 59, Issue:4

    Topics: Animals; Antineoplastic Agents; Cell Membrane; Cholesterol; Drug Combinations; Female; Glycerides; L

1994
Free radical-mediated lipid peroxidation in cells: oxidizability is a function of cell lipid bis-allylic hydrogen content.
    Biochemistry, 1994, Apr-19, Volume: 33, Issue:15

    Topics: Animals; Ascorbic Acid; Electron Spin Resonance Spectroscopy; Fatty Acids; Free Radicals; Hydrogen;

1994
Unidirectional membrane uptake of the ether lipid antineoplastic agent edelfosine by L1210 cells.
    Biochemical pharmacology, 1993, Jun-22, Volume: 45, Issue:12

    Topics: Animals; Antineoplastic Agents; Blood Proteins; Endocytosis; Humans; Kinetics; Leukemia L1210; Lipid

1993
Increased generation of lipid-derived and ascorbate free radicals by L1210 cells exposed to the ether lipid edelfosine.
    Cancer research, 1993, Feb-15, Volume: 53, Issue:4

    Topics: Animals; Antineoplastic Agents; Ascorbic Acid; Docosahexaenoic Acids; Dose-Response Relationship, Dr

1993
Synthesis and growth inhibitory properties of glycosides of 1-O-hexadecyl-2-O-methyl-sn-glycerol, analogs of the antitumor ether lipid ET-18-OCH3 (edelfosine).
    Journal of medicinal chemistry, 1996, Aug-16, Volume: 39, Issue:17

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line; Cell Survival; Female; Glycosides; Huma

1996
Membrane peroxidative damage enhancement by the ether lipid class of antineoplastic agents.
    Cancer research, 1992, Nov-01, Volume: 52, Issue:21

    Topics: Animals; Antineoplastic Agents; Ascorbic Acid; Cell Death; Drugs, Investigational; Fatty Acids; Free

1992
Sensitivity of leukemia cell lines to cytotoxic alkyl-lysophospholipids in relation to O-alkyl cleavage enzyme activities.
    Journal of the National Cancer Institute, 1987, Volume: 78, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship,

1987