edelfosine has been researched along with Leukemia, Myeloid, Acute in 12 studies
edelfosine: RN given refers to parent cpd
edelfosine : A racemate comprising equimolar amounts of (R)- and (S)-edelfosine.
1-octadecyl-2-methylglycero-3-phosphocholine : A glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.
Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The prolonged blood circulation potential of micellar formulations might improve the therapeutic potential of drug by increasing its bioavailability in the serum." | 1.43 | Transferrin-conjugated polymeric nanomedicine to enhance the anticancer efficacy of edelfosine in acute myeloid leukemia. ( Sun, Y; Sun, ZL, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marx, MH | 1 |
| Piantadosi, C | 1 |
| Noseda, A | 1 |
| Daniel, LW | 2 |
| Modest, EJ | 1 |
| Sun, Y | 1 |
| Sun, ZL | 1 |
| Wierenga, PK | 1 |
| Setroikromo, R | 1 |
| Kamps, G | 1 |
| Kampinga, HH | 1 |
| Vellenga, E | 1 |
| Heesbeen, EC | 1 |
| Rijksen, G | 2 |
| van Heugten, HG | 2 |
| Verdonck, LF | 2 |
| Vogler, WR | 3 |
| Civoli, F | 1 |
| Pauig, SB | 1 |
| Gajate, C | 1 |
| Santos-Beneit, AM | 1 |
| Macho, A | 1 |
| Lazaro, Md | 1 |
| Hernandez-De Rojas, A | 1 |
| Modolell, M | 1 |
| Muñoz, E | 1 |
| Mollinedo, F | 1 |
| Berdel, WE | 1 |
| Olson, AC | 2 |
| Winton, EF | 1 |
| Heffner, LT | 1 |
| Gordon, DS | 1 |
| Reed, CB | 1 |
| Tang, W | 1 |
| Ziboh, VA | 1 |
| Witteveen, EO | 1 |
| Rozemuller, E | 1 |
| Okamoto, S | 1 |
| Dulisch, I | 1 |
| Neumann, HA | 1 |
| Löhr, GW | 1 |
| Andreesen, R | 1 |
12 other studies available for edelfosine and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Synthesis and evaluation of neoplastic cell growth inhibition of 1-N-alkylamide analogues of glycero-3-phosphocholine.
Topics: Amides; Cell Division; Humans; Leukemia, Myeloid, Acute; Magnetic Resonance Spectroscopy; Phosphatid | 1988 |
Transferrin-conjugated polymeric nanomedicine to enhance the anticancer efficacy of edelfosine in acute myeloid leukemia.
Topics: Administration, Intravenous; Antineoplastic Agents; Apoptosis; Cell Cycle; Drug Liberation; Dynamic | 2016 |
Differences in heat sensitivity between normal and acute myeloid leukemic stem cells: feasibility of hyperthermic purging of leukemic cells from autologous stem cell grafts.
Topics: Animals; Bone Marrow Purging; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Hot | 2003 |
Influence of serum levels on leukemic cell destruction by the ether lipid ET-18-OCH3.
Topics: Antineoplastic Agents; Biological Factors; Bone Marrow Cells; Bone Marrow Purging; Cell Division; Ce | 1995 |
Bone marrow purging in acute leukemia with alkyl-lysophospholipids: a new family of anticancer drugs.
Topics: Antineoplastic Agents; Bone Marrow Purging; Bone Marrow Transplantation; Cyclophosphamide; Cytarabin | 1994 |
Differentiation of HL-60 cells distinguishes between cytostatic and cytotoxic effects of the alkylphospholipid ET-18-OCH3.
Topics: Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Survival; Dimethyl Sulfoxide; Dose- | 1996 |
Involvement of mitochondria and caspase-3 in ET-18-OCH(3)-induced apoptosis of human leukemic cells.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; DNA Fragmentation; Enzyme | 2000 |
Autologous bone marrow transplantation in acute leukemia with marrow purged with alkyl-lysophospholipid.
Topics: Adolescent; Adult; Antineoplastic Agents; Blood Platelets; Bone Marrow; Bone Marrow Cells; Bone Marr | 1992 |
Antineoplastic ether-linked phospholipid induces differentiation of acute myelogenous leukemic KG-1 cells into macrophage-like cells.
Topics: Antineoplastic Agents; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; Estera | 1991 |
Selective killing of malignant cells from leukemic patients by alkyl-lysophospholipid.
Topics: Adolescent; Adult; Aged; Blast Crisis; Bone Marrow; Bone Marrow Transplantation; Child; Colony-Formi | 1990 |
Elimination of leukemic cells by the combined use of ether lipids in vitro.
Topics: Blood; Cell Line; Cell Survival; Clone Cells; Drug Synergism; Humans; In Vitro Techniques; Leukemia, | 1987 |
Clonogenicity of normal and malignant hematopoietic progenitor cells after exposure to synthetic alkyl-lymphospholipids.
Topics: Animals; Antineoplastic Agents; Cell Line; Dose-Response Relationship, Drug; Hematopoiesis; Hematopo | 1985 |