edelfosine has been researched along with Kahler Disease in 3 studies
edelfosine: RN given refers to parent cpd
edelfosine : A racemate comprising equimolar amounts of (R)- and (S)-edelfosine.
1-octadecyl-2-methylglycero-3-phosphocholine : A glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.
Excerpt | Relevance | Reference |
---|---|---|
"Despite recent advances in treatment, multiple myeloma (MM) remains an incurable malignancy." | 1.36 | Lipid raft-targeted therapy in multiple myeloma. ( Blanco-Prieto, MJ; Campanero, MA; de la Iglesia-Vicente, J; Estella-Hermoso de Mendoza, A; Gajate, C; Mollinedo, F; Villa-Pulgarin, JA, 2010) |
" Dose-response curves after drug exposure for 4 and 24 hours reached plateaus at 75 and 25 microg/mL, respectively." | 1.29 | Response of human multiple myeloma-derived cell lines to alkyl-lysophospholipid. ( Cook, P; Dalton, WS; Fiederlein, RL; Glasser, L; Powis, G; Vogler, WR, 1996) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (33.33) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Mollinedo, F | 2 |
de la Iglesia-Vicente, J | 1 |
Gajate, C | 2 |
Estella-Hermoso de Mendoza, A | 1 |
Villa-Pulgarin, JA | 1 |
Campanero, MA | 1 |
Blanco-Prieto, MJ | 1 |
Glasser, L | 1 |
Dalton, WS | 1 |
Fiederlein, RL | 1 |
Cook, P | 1 |
Powis, G | 1 |
Vogler, WR | 1 |
3 other studies available for edelfosine and Kahler Disease
Article | Year |
---|---|
Lipid raft-targeted therapy in multiple myeloma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Humans; Membran | 2010 |
Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid rafts.
Topics: Apoptosis; Caspase 8; Cell Line, Tumor; Cell Proliferation; fas Receptor; Fas-Associated Death Domai | 2007 |
Response of human multiple myeloma-derived cell lines to alkyl-lysophospholipid.
Topics: Antineoplastic Agents, Alkylating; Calcium; Dose-Response Relationship, Drug; Drug Resistance, Neopl | 1996 |