edelfosine and Kahler Disease studies

edelfosine and Kahler Disease

edelfosine has been researched along with Kahler Disease in 3 studies

edelfosine: RN given refers to parent cpd
edelfosine : A racemate comprising equimolar amounts of (R)- and (S)-edelfosine.
1-octadecyl-2-methylglycero-3-phosphocholine : A glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.

Research Excerpts

Excerpt	Relevance	Reference
"Despite recent advances in treatment, multiple myeloma (MM) remains an incurable malignancy."	1.36	Lipid raft-targeted therapy in multiple myeloma. ( Blanco-Prieto, MJ; Campanero, MA; de la Iglesia-Vicente, J; Estella-Hermoso de Mendoza, A; Gajate, C; Mollinedo, F; Villa-Pulgarin, JA, 2010)
" Dose-response curves after drug exposure for 4 and 24 hours reached plateaus at 75 and 25 microg/mL, respectively."	1.29	Response of human multiple myeloma-derived cell lines to alkyl-lysophospholipid. ( Cook, P; Dalton, WS; Fiederlein, RL; Glasser, L; Powis, G; Vogler, WR, 1996)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (33.33)	18.2507
2000's	1 (33.33)	29.6817
2010's	1 (33.33)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

1 (33.33)

18.2507

2000's

1 (33.33)

29.6817

2010's

1 (33.33)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Mollinedo, F	2
de la Iglesia-Vicente, J	1
Gajate, C	2
Estella-Hermoso de Mendoza, A	1
Villa-Pulgarin, JA	1
Campanero, MA	1
Blanco-Prieto, MJ	1
Glasser, L	1
Dalton, WS	1
Fiederlein, RL	1
Cook, P	1
Powis, G	1
Vogler, WR	1

Studies

Mollinedo, F

de la Iglesia-Vicente, J

Gajate, C

Estella-Hermoso de Mendoza, A

Villa-Pulgarin, JA

Campanero, MA

Blanco-Prieto, MJ

Glasser, L

Dalton, WS

Fiederlein, RL

Cook, P

Powis, G

Vogler, WR

Other Studies

3 other studies available for edelfosine and Kahler Disease

Article	Year
Lipid raft-targeted therapy in multiple myeloma. Oncogene, 2010, Jul-01, Volume: 29, Issue:26 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Humans; Membran	2010
Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid rafts. Blood, 2007, Jan-15, Volume: 109, Issue:2 Topics: Apoptosis; Caspase 8; Cell Line, Tumor; Cell Proliferation; fas Receptor; Fas-Associated Death Domai	2007
Response of human multiple myeloma-derived cell lines to alkyl-lysophospholipid. Experimental hematology, 1996, Volume: 24, Issue:2 Topics: Antineoplastic Agents, Alkylating; Calcium; Dose-Response Relationship, Drug; Drug Resistance, Neopl	1996

Article

Year

Lipid raft-targeted therapy in multiple myeloma.

Oncogene, 2010, Jul-01, Volume: 29, Issue:26

Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Humans; Membran

2010

Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid rafts.

Blood, 2007, Jan-15, Volume: 109, Issue:2

Topics: Apoptosis; Caspase 8; Cell Line, Tumor; Cell Proliferation; fas Receptor; Fas-Associated Death Domai

2007

Response of human multiple myeloma-derived cell lines to alkyl-lysophospholipid.

Experimental hematology, 1996, Volume: 24, Issue:2

Topics: Antineoplastic Agents, Alkylating; Calcium; Dose-Response Relationship, Drug; Drug Resistance, Neopl

1996