edelfosine has been researched along with Invasiveness, Neoplasm in 12 studies
edelfosine: RN given refers to parent cpd
edelfosine : A racemate comprising equimolar amounts of (R)- and (S)-edelfosine.
1-octadecyl-2-methylglycero-3-phosphocholine : A glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The MCF-7/6 human breast cancer cells were used as negative control since their E-cadherin/catenin complex is functional in cells grown on solid substrate but not in suspension." | 1.31 | Alkyl-lysophospholipid 1-O-octadecyl-2-O-methyl- glycerophosphocholine induces invasion through episialin-mediated neutralization of E-cadherin in human mammary MCF-7 cells in vitro. ( Bruyneel, EA; Delannoy, P; Goeman, JL; Hilkens, J; Huet, G; Krzewinski-Recchi, MA; Mareel, MM; Oomen, LC; Philippé, J; Steelant, WF; Van der Eycken, J, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Van Slambrouck, S | 3 |
| Steelant, WF | 4 |
| Steinestel, K | 1 |
| Eder, S | 1 |
| Ehinger, K | 1 |
| Schneider, J | 1 |
| Genze, F | 1 |
| Winkler, E | 1 |
| Wardelmann, E | 1 |
| Schrader, AJ | 1 |
| Steinestel, J | 1 |
| Jaffrès, PA | 1 |
| Gajate, C | 1 |
| Bouchet, AM | 1 |
| Couthon-Gourvès, H | 1 |
| Chantôme, A | 1 |
| Potier-Cartereau, M | 1 |
| Besson, P | 1 |
| Bougnoux, P | 1 |
| Mollinedo, F | 1 |
| Vandier, C | 1 |
| Lopez, M | 1 |
| Recchi, MA | 1 |
| Boilly-Marer, Y | 1 |
| Bruyneel, EA | 5 |
| Delannoy, P | 2 |
| Verbert, A | 1 |
| Van Den Eeckhout, EG | 1 |
| Deforce, D | 1 |
| Droller, MJ | 1 |
| Slaton, JW | 1 |
| Hampton, JA | 1 |
| Selman, SH | 1 |
| van Larebeke, NA | 1 |
| Mareel, MM | 4 |
| Goeman, JL | 1 |
| Philippé, J | 1 |
| Oomen, LC | 1 |
| Hilkens, J | 1 |
| Krzewinski-Recchi, MA | 1 |
| Huet, G | 1 |
| Van der Eycken, J | 1 |
| Mareel, M | 1 |
| Bracke, M | 1 |
| Bruyneel, E | 1 |
| Van Larebeke, N | 1 |
| De Mets, M | 1 |
| Storme, GA | 2 |
| Schallier, DC | 1 |
| Bolscher, JG | 1 |
| Berdel, WE | 2 |
| van Blitterswijk, WJ | 1 |
| De Bruyne, GK | 1 |
3 reviews available for edelfosine and Invasiveness, Neoplasm
| Article | Year |
|---|---|
1-O-octadecyl-2-O-methylglycero-3-phosphocholine (Edelfosine) and cancer cell invasion: a short review.
Topics: Animals; Antineoplastic Agents; Humans; Neoplasm Invasiveness; Neoplasms; Phospholipid Ethers; Signa | 2014 |
Alkyl ether lipids, ion channels and lipid raft reorganization in cancer therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Movement; Drug Design; Glycolipids; Humans; Ion Chan | 2016 |
Invasion and metastasis control: implications for increased therapeutic index of antitumor drugs.
Topics: Antineoplastic Agents; Catechin; Dipyridamole; Glycoproteins; Humans; Microtubules; Neoplasm Invasiv | 1990 |
9 other studies available for edelfosine and Invasiveness, Neoplasm
| Article | Year |
|---|---|
The small conductance calcium-activated potassium channel 3 (SK3) is a molecular target for Edelfosine to reduce the invasive potential of urothelial carcinoma cells.
Topics: Adult; Aged; Calcium; Carcinoma; Cell Movement; Female; Gene Expression Regulation, Neoplastic; Huma | 2016 |
Clustering of monosialyl-Gb5 initiates downstream signalling events leading to invasion of MCF-7 breast cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Female; Focal Adhesi | 2007 |
Edelfosine protects precultured heart fragments against the invasion of malignant cells through altered sialylation.
Topics: Animals; Antineoplastic Agents; Biotinylation; Blotting, Western; Cell Membrane; Chick Embryo; Drug | 2007 |
This month in Investigative Urology. A commentary on suramin demonstrates in vitro toxicity against transitional cell carcinoma cell lines and exposure to alkyllysophospholipids inhibits in vitro invasion of transitional cell carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Transitional Cell; Drug Screening Assays, Antitumor; Humans; Neopl | 1994 |
Exposure to alkyllysophospholipids inhibits in vitro invasion of transitional cell carcinoma.
Topics: Animals; Antineoplastic Agents; Carcinoma, Transitional Cell; Drug Screening Assays, Antitumor; Huma | 1994 |
An anti-invasive concentration of the alkyl-lysophospholipid ET-18-OCH3 enhances the motility of embryonal chick heart cells cultured on solid substrate.
Topics: Animals; Cell Membrane; Cell Size; Cells, Cultured; Chick Embryo; Heart; In Vitro Techniques; Myocar | 1994 |
Alkyl-lysophospholipid 1-O-octadecyl-2-O-methyl- glycerophosphocholine induces invasion through episialin-mediated neutralization of E-cadherin in human mammary MCF-7 cells in vitro.
Topics: Antibodies, Monoclonal; beta Catenin; Biotinylation; Blotting, Northern; Blotting, Western; Breast N | 2001 |
Effect of lipid derivatives on invasion in vitro and on surface glycoproteins of three rodent cell types.
Topics: Animals; Antineoplastic Agents; Cell Line; Lysophospholipids; Membrane Glycoproteins; Mice; Mice, In | 1987 |
Antiinvasive effect of racemic 1-O-octadecyl-2-O-methylglycero-3-phosphocholine on MO4 mouse fibrosarcoma cells in vitro.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Chickens; Drug Ev | 1985 |