Page last updated: 2024-10-21

edelfosine and Inflammation

edelfosine has been researched along with Inflammation in 1 studies

edelfosine: RN given refers to parent cpd
edelfosine : A racemate comprising equimolar amounts of (R)- and (S)-edelfosine.
1-octadecyl-2-methylglycero-3-phosphocholine : A glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"Taken together, these data suggest that the combined treatment of PZQ and edelfosine promotes a high decrease in granuloma formation, as well as in the cellular immune response that underlies granuloma development, with changes in the cytokine patterns, and may provide a promising and effective strategy for a prophylactic treatment of schistosomiasis."7.81Inhibition of Granulomatous Inflammation and Prophylactic Treatment of Schistosomiasis with a Combination of Edelfosine and Praziquantel. ( López-Abán, J; Mollinedo, F; Muro, A; Rojas-Caraballo, J; Varela-M, RE; Yepes, E, 2015)
"Taken together, these data suggest that the combined treatment of PZQ and edelfosine promotes a high decrease in granuloma formation, as well as in the cellular immune response that underlies granuloma development, with changes in the cytokine patterns, and may provide a promising and effective strategy for a prophylactic treatment of schistosomiasis."3.81Inhibition of Granulomatous Inflammation and Prophylactic Treatment of Schistosomiasis with a Combination of Edelfosine and Praziquantel. ( López-Abán, J; Mollinedo, F; Muro, A; Rojas-Caraballo, J; Varela-M, RE; Yepes, E, 2015)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yepes, E1
Varela-M, RE1
López-Abán, J1
Rojas-Caraballo, J1
Muro, A1
Mollinedo, F1

Other Studies

1 other study available for edelfosine and Inflammation

ArticleYear
Inhibition of Granulomatous Inflammation and Prophylactic Treatment of Schistosomiasis with a Combination of Edelfosine and Praziquantel.
    PLoS neglected tropical diseases, 2015, Volume: 9, Issue:7

    Topics: Animals; Anthelmintics; Cytokines; Gene Expression Regulation; Granuloma; Inflammation; Mice; Phosph

2015