edelfosine has been researched along with HIV Coinfection in 2 studies
edelfosine: RN given refers to parent cpd
edelfosine : A racemate comprising equimolar amounts of (R)- and (S)-edelfosine.
1-octadecyl-2-methylglycero-3-phosphocholine : A glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Edelfosine is an FDA-approved investigational, anti-neoplastic drug." | 1.72 | Edelfosine reactivates latent HIV-1 reservoirs in myeloid cells through activation of NF-κB and AP1 pathway. ( Gaur, R; Muhammadi, MK; Rai, M; Rawat, K, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rai, M | 1 |
| Rawat, K | 1 |
| Muhammadi, MK | 1 |
| Gaur, R | 1 |
| Lucas, A | 1 |
| Kim, Y | 1 |
| Rivera-Pabon, O | 1 |
| Chae, S | 1 |
| Kim, DH | 1 |
| Kim, B | 1 |
2 other studies available for edelfosine and HIV Coinfection
| Article | Year |
|---|---|
Edelfosine reactivates latent HIV-1 reservoirs in myeloid cells through activation of NF-κB and AP1 pathway.
Topics: CD4-Positive T-Lymphocytes; HIV Infections; HIV-1; Humans; Myeloid Cells; NF-kappa B; Phospholipid E | 2022 |
Targeting the PI3K/Akt cell survival pathway to induce cell death of HIV-1 infected macrophages with alkylphospholipid compounds.
Topics: Anti-HIV Agents; Cell Death; Cell Line; Cells, Cultured; HIV Infections; HIV-1; Humans; Macrophages; | 2010 |