Page last updated: 2024-10-21

edelfosine and Extravascular Hemolysis

edelfosine has been researched along with Extravascular Hemolysis in 7 studies

edelfosine: RN given refers to parent cpd
edelfosine : A racemate comprising equimolar amounts of (R)- and (S)-edelfosine.
1-octadecyl-2-methylglycero-3-phosphocholine : A glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.

Research Excerpts

ExcerptRelevanceReference
"5 mg/kg (no observed adverse effects) and 62."1.32Toxicity and disposition of TLC ELL-12 (liposomal antitumor ether lipid) in Sprague-Dawley rats. ( Bhamra, R; Bolcsak, LE; Cavanaugh, C; Roberts, P; Stevens, R; Swenson, CE, 2003)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (85.71)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fos, E1
Suesa, N1
Borras, L1
Lobato, C1
Banfi, P1
Gambetta, RA1
Zunino, F1
Mauleón, D1
Carganico, G1
Bhamra, R1
Bolcsak, LE1
Roberts, P1
Stevens, R1
Cavanaugh, C1
Swenson, CE1
Ahmad, I3
Filep, JJ1
Franklin, JC2
Janoff, AS3
Masters, GR1
Pattassery, J1
Peters, A1
Schupsky, JJ1
Zha, Y2
Mayhew, E3
Lundberg, BB1
Peters, AC1
Pushkareva, MY1
Bhatia, S1
Dause, R1
Filep, J1
Kaisheva, E1
Perkins, WR1
Kötting, J1
Marschner, NW1
Neumüller, W1
Unger, C1
Eibl, H1

Other Studies

7 other studies available for edelfosine and Extravascular Hemolysis

ArticleYear
Synthesis of alkyl chain-modified ether lipids and evaluation of their in vitro cytotoxicity.
    Journal of medicinal chemistry, 1995, Mar-31, Volume: 38, Issue:7

    Topics: Animals; Cell Division; Cell Survival; Chemical Phenomena; Chemistry, Physical; Growth Inhibitors; H

1995
Toxicity and disposition of TLC ELL-12 (liposomal antitumor ether lipid) in Sprague-Dawley rats.
    Anti-cancer drugs, 2003, Volume: 14, Issue:3

    Topics: Animals; Antineoplastic Agents; Area Under Curve; Carbon Isotopes; Cell Line, Tumor; Chromatography,

2003
Enhanced therapeutic effects of liposome-associated 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine.
    Cancer research, 1997, May-15, Volume: 57, Issue:10

    Topics: Animals; Antineoplastic Agents; Ascitic Fluid; Carcinoma, Lewis Lung; Drug Screening Assays, Antitum

1997
Ether lipids enhance the cytotoxic effect of teniposide and paclitaxel in liposomes against leukaemic cells in culture.
    Anti-cancer drug design, 1997, Volume: 12, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Drug Antagonism; Drug Synergism; Hemolysis; HL-60 Cells; Humans;

1997
Growth inhibitory effects of liposome-associated 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine.
    Lipids, 1997, Volume: 32, Issue:10

    Topics: Animals; Calcium; Cell Division; DNA Fragmentation; Drug Resistance, Neoplasm; Hemolysis; Humans; Li

1997
Stability of association of 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine with liposomes is composition dependent.
    Biochimica et biophysica acta, 1997, Oct-02, Volume: 1329, Issue:1

    Topics: Centrifugation, Density Gradient; Cholesterol; Erythrocytes; Fluoresceins; Fluorescent Dyes; Hemolys

1997
Hexadecylphosphocholine and octadecyl-methyl-glycero-3-phosphocholine: a comparison of hemolytic activity, serum binding and tissue distribution.
    Progress in experimental tumor research, 1992, Volume: 34

    Topics: Animals; Antineoplastic Agents; Female; Hemolysis; Phospholipid Ethers; Phosphorylcholine; Rats; Rat

1992