edelfosine has been researched along with Experimental Neoplasms in 10 studies
edelfosine: RN given refers to parent cpd
edelfosine : A racemate comprising equimolar amounts of (R)- and (S)-edelfosine.
1-octadecyl-2-methylglycero-3-phosphocholine : A glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This provided an increase in relative oral bioavailability of 1500% after a single oral administration of drug-loaded LNs, maintaining edelfosine plasma levels over 7 days in contrast to a single oral administration of edelfosine solution, which presented a relative oral bioavailability of 10%." | 5.38 | Complete inhibition of extranodal dissemination of lymphoma by edelfosine-loaded lipid nanoparticles. ( Blanco-Prieto, MJ; Campanero, MA; de la Iglesia-Vicente, J; Estella-Hermoso de Mendoza, A; Lana, H; Mollinedo, F; Villa-Pulgarin, JA, 2012) |
| "This provided an increase in relative oral bioavailability of 1500% after a single oral administration of drug-loaded LNs, maintaining edelfosine plasma levels over 7 days in contrast to a single oral administration of edelfosine solution, which presented a relative oral bioavailability of 10%." | 1.38 | Complete inhibition of extranodal dissemination of lymphoma by edelfosine-loaded lipid nanoparticles. ( Blanco-Prieto, MJ; Campanero, MA; de la Iglesia-Vicente, J; Estella-Hermoso de Mendoza, A; Lana, H; Mollinedo, F; Villa-Pulgarin, JA, 2012) |
| "with MDA-MB 231 human breast carcinoma cells." | 1.30 | Effects of iron supplementation and ET-18-OCH3 on MDA-MB 231 breast carcinomas in nude mice consuming a fish oil diet. ( Barnes, CJ; Cameron, IL; Hardman, WE; Knight, CW, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bittman, R | 1 |
| Byun, HS | 1 |
| Mercier, B | 1 |
| Salari, H | 1 |
| Estella-Hermoso de Mendoza, A | 1 |
| Campanero, MA | 1 |
| Lana, H | 1 |
| Villa-Pulgarin, JA | 1 |
| de la Iglesia-Vicente, J | 1 |
| Mollinedo, F | 1 |
| Blanco-Prieto, MJ | 1 |
| Bhamra, R | 1 |
| Bolcsak, LE | 1 |
| Ahmad, I | 1 |
| Schupsky, J | 1 |
| Roberts, P | 1 |
| Stevens, R | 1 |
| Cavanaugh, C | 1 |
| Swenson, CE | 1 |
| Berdel, WE | 3 |
| Bausert, WR | 1 |
| Weltzien, HU | 1 |
| Modolell, ML | 1 |
| Widmann, KH | 1 |
| Munder, PG | 1 |
| Hardman, WE | 1 |
| Barnes, CJ | 1 |
| Knight, CW | 1 |
| Cameron, IL | 1 |
| Okamoto, S | 1 |
| Santos, GW | 1 |
| Colvin, OM | 1 |
| Berger, MR | 1 |
| Schmähl, D | 1 |
| Bolscher, JG | 1 |
| Schallier, DC | 1 |
| van Rooy, H | 1 |
| Storme, GA | 1 |
| Smets, LA | 1 |
3 reviews available for edelfosine and Experimental Neoplasms
| Article | Year |
|---|---|
Ether lipids in cancer chemotherapy.
Topics: Animals; Antineoplastic Agents; Bone Marrow Transplantation; Drug Evaluation; Drug Evaluation, Precl | 1990 |
Ether lipids and derivatives as investigational anticancer drugs. A brief review.
Topics: Animals; Antineoplastic Agents; Drug Evaluation; Humans; Leukemia, Experimental; Mice; Neoplasms, Ex | 1990 |
Pharmacological purging of bone marrow with reference to autografting.
Topics: Adolescent; Adult; Animals; Bleomycin; Bone Marrow; Bone Marrow Transplantation; Cell Separation; Ch | 1986 |
1 trial available for edelfosine and Experimental Neoplasms
| Article | Year |
|---|---|
Pharmacological purging of bone marrow with reference to autografting.
Topics: Adolescent; Adult; Animals; Bleomycin; Bone Marrow; Bone Marrow Transplantation; Cell Separation; Ch | 1986 |
7 other studies available for edelfosine and Experimental Neoplasms
| Article | Year |
|---|---|
2'-(Trimethylammonio)ethyl 4-(hexadecyloxy)-3(S)-methoxybutanephosphonate: a novel potent antineoplastic agent.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; | 1993 |
Complete inhibition of extranodal dissemination of lymphoma by edelfosine-loaded lipid nanoparticles.
Topics: Animals; Diglycerides; Fatty Acids; Humans; Leukemic Infiltration; Lymph Nodes; Lymphoma; Mice; Nano | 2012 |
Activity, pharmacokinetics and tissue distribution of TLC ELL-12 (liposomal antitumor ether lipid) in rats with transplantable, s.c. methylnitrosourea-induced tumors.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Area Under Curve; Female; Half-Life; Injections, | 2003 |
The influence of alkyl-lysophospholipids and lysophospholipid-activated macrophages on the development of metastasis of 3-Lewis lung carcinoma.
Topics: Animals; Female; Lung Neoplasms; Lysophosphatidylcholines; Macrophages; Mice; Mice, Inbred C57BL; Ne | 1980 |
Effects of iron supplementation and ET-18-OCH3 on MDA-MB 231 breast carcinomas in nude mice consuming a fish oil diet.
Topics: Animals; Breast Neoplasms; Dietary Fats, Unsaturated; Eicosanoids; Fish Oils; Growth Inhibitors; Hum | 1997 |
Modulation of chemical carcinogenesis in rats by alkyl lysophospholipids.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents; Dose-Respons | 1987 |
Modification of cell surface carbohydrates and invasive behavior by an alkyl lysophospholipid.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cu | 1988 |