Page last updated: 2024-10-21

edelfosine and Experimental Leukemia

edelfosine has been researched along with Experimental Leukemia in 9 studies

edelfosine: RN given refers to parent cpd
edelfosine : A racemate comprising equimolar amounts of (R)- and (S)-edelfosine.
1-octadecyl-2-methylglycero-3-phosphocholine : A glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.

Research Excerpts

ExcerptRelevanceReference
" All the mice given cells not treated with ALP succumbed to leukemia, whereas there was a dose-response increase in survival in those given ALP treated cells."1.28Purging leukemia remission marrows with alkyl-lysophospholipids, preclinical and clinical results. ( Berdel, WE; Glasser, L; Okamoto, S; Olson, AC; Vogler, WR, 1990)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19906 (66.67)18.7374
1990's3 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glasser, L3
Somberg, LB2
Vogler, WR4
Shoji, M2
Fukuhara, T1
Winton, EF1
Berdel, WE3
Olson, AC2
Okamoto, S2
Kuo, JF1
Girard, PR1
Mazzei, GJ1
Turner, RS1
Su, HD1
Berger, MR2
Schmähl, D2
Leder, GH1
Fiebig, HH1
Wallbrecher, E1
Winterhalter, BR1
Löhr, GW1

Reviews

1 review available for edelfosine and Experimental Leukemia

ArticleYear
Ether lipids and derivatives as investigational anticancer drugs. A brief review.
    Onkologie, 1990, Volume: 13, Issue:4

    Topics: Animals; Antineoplastic Agents; Drug Evaluation; Humans; Leukemia, Experimental; Mice; Neoplasms, Ex

1990

Other Studies

8 other studies available for edelfosine and Experimental Leukemia

ArticleYear
Purging murine leukemic marrow with alkyl-lysophospholipids.
    Blood, 1984, Volume: 64, Issue:6

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; Colony-Forming Units Assay; Gr

1984
Different mechanisms of inhibition by alkyl-lysophospholipid and phorbol ester of granulocyte-macrophage colony-stimulating factor binding to human leukemic cell lines.
    Experimental hematology, 1994, Volume: 22, Issue:1

    Topics: Antineoplastic Agents; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Iodine Radioisotope

1994
Purging leukemia remission marrows with alkyl-lysophospholipids, preclinical and clinical results.
    Progress in clinical and biological research, 1990, Volume: 333

    Topics: Acute Disease; Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplan

1990
Phospholipid/calcium-dependent protein kinase (protein kinase C) system: a major site of bioregulation.
    Advances in enzyme regulation, 1986, Volume: 25

    Topics: Animals; Antineoplastic Agents; Electrophoresis, Polyacrylamide Gel; Estrogen Antagonists; Humans; K

1986
Protection by the alkyllysophospholipid, 1-octadecyl-2-methoxy-rac-glycero-3-phosphocholine, but not by the retinoid etretinate against leukemia development in DMBA-treated Long-Evans rats.
    Cancer letters, 1986, Volume: 30, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Etretinate; Female; Leukemia, Experimental; Lysophosphati

1986
Modulation of chemical carcinogenesis in rats by alkyl lysophospholipids.
    Lipids, 1987, Volume: 22, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents; Dose-Respons

1987
Experimental studies on the role of alkyl lysophospholipids in autologous bone marrow transplantation.
    Lipids, 1987, Volume: 22, Issue:11

    Topics: Animals; Bone Marrow; Bone Marrow Transplantation; Humans; Leukemia, Experimental; Lysophospholipids

1987
In vitro and in vivo cytotoxicity of alkyl lysophospholipid ET-18-OCH3 and thioether lipid BM 41.440.
    Lipids, 1987, Volume: 22, Issue:11

    Topics: Animals; Antineoplastic Agents; Cell Survival; Cytotoxins; Glyceryl Ethers; Humans; Injections, Intr

1987