Page last updated: 2024-10-21

edelfosine and Cancer of Pancreas

edelfosine has been researched along with Cancer of Pancreas in 2 studies

edelfosine: RN given refers to parent cpd
edelfosine : A racemate comprising equimolar amounts of (R)- and (S)-edelfosine.
1-octadecyl-2-methylglycero-3-phosphocholine : A glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.

Research Excerpts

ExcerptRelevanceReference
"Edelfosine was taken up in significant amounts by pancreatic cancer cells and induced caspase- and mitochondrial-mediated apoptosis."1.38Antitumor alkyl-lysophospholipid analog edelfosine induces apoptosis in pancreatic cancer by targeting endoplasmic reticulum. ( Alvarez, J; Dakir, el-H; Fonteriz, RI; Gajate, C; Matos-da-Silva, M; Mollinedo, F, 2012)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bello, C1
Bai, J1
Zambron, BK1
Elías-Rodríguez, P1
Gajate, C2
Robina, I1
Caffa, I1
Cea, M1
Montecucco, F1
Nencioni, A1
Nahimana, A1
Aubry, D1
Breton, C1
Duchosal, MA1
Mollinedo, F2
Vogel, P1
Matos-da-Silva, M1
Dakir, el-H1
Fonteriz, RI1
Alvarez, J1

Other Studies

2 other studies available for edelfosine and Cancer of Pancreas

ArticleYear
Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cells.
    European journal of medicinal chemistry, 2018, Apr-25, Volume: 150

    Topics: Antineoplastic Agents; Cell Death; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug;

2018
Antitumor alkyl-lysophospholipid analog edelfosine induces apoptosis in pancreatic cancer by targeting endoplasmic reticulum.
    Oncogene, 2012, May-24, Volume: 31, Issue:21

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; DNA-Binding Proteins; Endoplasmic Retic

2012