Page last updated: 2024-10-21

edelfosine and Cancer of Lung

edelfosine has been researched along with Cancer of Lung in 8 studies

edelfosine: RN given refers to parent cpd
edelfosine : A racemate comprising equimolar amounts of (R)- and (S)-edelfosine.
1-octadecyl-2-methylglycero-3-phosphocholine : A glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.

Research Excerpts

ExcerptRelevanceReference
"Lung cancer is the most prevalent cancer and a high fatality disease."1.48Edelfosine: An Antitumor Drug Prototype. ( Barbuto, JAM; Costa, CJS; de Azevedo, RA; Ferreira, AK; Ferro, ES; Jorge, SD; Mambelli, LI; Pettinati, TN; Ramos, RN; Rodrigues, CP; Teixeira, SF, 2018)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's2 (25.00)18.2507
2000's2 (25.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Teixeira, SF1
Rodrigues, CP1
Costa, CJS1
Pettinati, TN1
de Azevedo, RA1
Mambelli, LI1
Jorge, SD1
Ramos, RN1
Ferro, ES1
Barbuto, JAM1
Ferreira, AK1
González-Fernández, Y1
Brown, HK1
Patiño-García, A1
Heymann, D1
Blanco-Prieto, MJ1
Shafer, SH2
Williams, CL2
Berdel, WE2
Bausert, WR1
Weltzien, HU1
Modolell, ML1
Widmann, KH1
Munder, PG1
Marino-Albernas, JR1
Bittman, R1
Peters, A1
Mayhew, E1
Strassheim, D1
Phelps, SH1
Lu, X1
Arthur, G1
Storme, GA1
van Blitterswijk, WJ1
Bruyneel, EA1
De Bruyne, GK1
Mareel, MM1

Other Studies

8 other studies available for edelfosine and Cancer of Lung

ArticleYear
Edelfosine: An Antitumor Drug Prototype.
    Anti-cancer agents in medicinal chemistry, 2018, Volume: 18, Issue:6

    Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; Cell Survival; Dose-Re

2018
Oral administration of edelfosine encapsulated lipid nanoparticles causes regression of lung metastases in pre-clinical models of osteosarcoma.
    Cancer letters, 2018, 08-28, Volume: 430

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cell

2018
Non-small and small cell lung carcinoma cell lines exhibit cell type-specific sensitivity to edelfosine-induced cell death and different cell line-specific responses to edelfosine treatment.
    International journal of oncology, 2003, Volume: 23, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Cycle;

2003
The influence of alkyl-lysophospholipids and lysophospholipid-activated macrophages on the development of metastasis of 3-Lewis lung carcinoma.
    European journal of cancer, 1980, Volume: 16, Issue:9

    Topics: Animals; Female; Lung Neoplasms; Lysophosphatidylcholines; Macrophages; Mice; Mice, Inbred C57BL; Ne

1980
Synthesis and growth inhibitory properties of glycosides of 1-O-hexadecyl-2-O-methyl-sn-glycerol, analogs of the antitumor ether lipid ET-18-OCH3 (edelfosine).
    Journal of medicinal chemistry, 1996, Aug-16, Volume: 39, Issue:17

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line; Cell Survival; Female; Glycosides; Huma

1996
Small cell lung carcinoma exhibits greater phospholipase C-beta1 expression and edelfosine resistance compared with non-small cell lung carcinoma.
    Cancer research, 2000, May-15, Volume: 60, Issue:10

    Topics: Antineoplastic Agents; Calcium; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Drug Resistan

2000
The differential susceptibility of A427 and A549 cell lines to the growth-inhibitory effects of ET-18-OCH3 does not correlate with the relative effects of the alkyl-lysophospholipid on the incorporation of fatty acids into cellular phospholipids.
    Cancer research, 1992, May-15, Volume: 52, Issue:10

    Topics: Acylation; Cell Division; Colonic Neoplasms; Drug Screening Assays, Antitumor; Fatty Acids; Humans;

1992
Antiinvasive effect of racemic 1-O-octadecyl-2-O-methylglycero-3-phosphocholine on MO4 mouse fibrosarcoma cells in vitro.
    Cancer research, 1985, Volume: 45, Issue:1

    Topics: Animals; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Chickens; Drug Ev

1985