edelfosine has been researched along with Adenocarcinoma in 2 studies
edelfosine: RN given refers to parent cpd
edelfosine : A racemate comprising equimolar amounts of (R)- and (S)-edelfosine.
1-octadecyl-2-methylglycero-3-phosphocholine : A glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The ether lipid analogue 1-octadecyl-2-methyl-rac-glycero-3-phosphocholine (ET-18-OCH3) has been shown to be a direct inhibitor of Swiss 3T3 fibroblast and BG1 ovarian adenocarcinoma cell cytosolic phosphoinositide selective phospholipase C (PIPLC) using [3H]-phosphatidylinositol-(4, 5)-bisphosphate ([3H]PIP2) as the substrate." | 3.68 | Selective inhibition of phosphatidylinositol phospholipase C by cytotoxic ether lipid analogues. ( Gratas, C; Melder, D; Modest, EJ; Powis, G; Riebow, J; Seewald, MJ, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Powis, G | 1 |
| Seewald, MJ | 1 |
| Gratas, C | 1 |
| Melder, D | 1 |
| Riebow, J | 1 |
| Modest, EJ | 2 |
| Noseda, A | 1 |
| Berens, ME | 1 |
| White, JG | 1 |
2 other studies available for edelfosine and Adenocarcinoma
| Article | Year |
|---|---|
Selective inhibition of phosphatidylinositol phospholipase C by cytotoxic ether lipid analogues.
Topics: 3T3 Cells; Adenocarcinoma; Animals; Cell Division; Choline; Female; Mice; Ovarian Neoplasms; Phospha | 1992 |
In vitro antiproliferative activity of combinations of ether lipid analogues and DNA-interactive agents against human tumor cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Division | 1988 |