edelfosine has been researched along with Acute Promyelocytic Leukemia in 11 studies
edelfosine: RN given refers to parent cpd
edelfosine : A racemate comprising equimolar amounts of (R)- and (S)-edelfosine.
1-octadecyl-2-methylglycero-3-phosphocholine : A glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 9 (81.82) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morris-Natschke, SL | 1 |
| Meyer, KL | 1 |
| Marasco, CJ | 1 |
| Piantadosi, C | 1 |
| Rossi, F | 1 |
| Godwin, PL | 1 |
| Modest, EJ | 2 |
| Jones, EW | 1 |
| Manning, R | 1 |
| Diomede, L | 1 |
| Colotta, F | 1 |
| Piovani, B | 1 |
| Re, F | 1 |
| Salmona, M | 1 |
| Small, GW | 1 |
| Strum, JC | 1 |
| Daniel, LW | 1 |
| Tsutsumi, T | 1 |
| Tokumura, A | 1 |
| Kitazawa, S | 1 |
| Hoffman, DR | 1 |
| Thomas, VL | 1 |
| Snyder, F | 3 |
| Hochhuth, C | 1 |
| Berkovic, D | 1 |
| Eibl, H | 2 |
| Unger, C | 1 |
| Doenecke, D | 1 |
| Workman, P | 1 |
| Donaldson, J | 1 |
| Lohmeyer, M | 1 |
| Shoji, M | 1 |
| Raynor, RL | 1 |
| Fleer, EA | 1 |
| Vogler, WR | 1 |
| Kuo, JF | 1 |
| Vallari, DS | 2 |
| Record, M | 1 |
| Smith, ZL | 2 |
11 other studies available for edelfosine and Acute Promyelocytic Leukemia
| Article | Year |
|---|---|
Synthesis of quaternary amine ether lipids and evaluation of neoplastic cell growth inhibitory properties.
Topics: Antineoplastic Agents; Ethers; Humans; Leukemia, Promyelocytic, Acute; Lipids; Protein Kinase C; Pyr | 1990 |
Cytotoxic effects of membrane-active agents in human leukaemia cell lines.
Topics: Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Culture Media, Serum-Free; Dibucaine | 1995 |
Induction of apoptosis in human leukemic cells by the ether lipid 1-octadecyl-2-methyl-rac-glycero-3-phosphocholine. A possible basis for its selective action.
Topics: Antineoplastic Agents; Apoptosis; Cholesterol; DNA, Neoplasm; Drug Resistance; Humans; Leukemia, Pro | 1993 |
Characterization of an HL-60 cell variant resistant to the antineoplastic ether lipid 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine.
Topics: Antineoplastic Agents; Biological Transport; Culture Media, Serum-Free; Dose-Response Relationship, | 1997 |
Undifferentiated HL-60 cells internalize an antitumor alkyl ether phospholipid more rapidly than resistant K562 cells.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Cytoskeleton; HL-60 Cells; Humans; Leukemia, Erythrob | 1998 |
Inhibition of cellular transport systems by alkyl phospholipid analogs in HL-60 human leukemia cells.
Topics: Antineoplastic Agents; Biological Transport; Cell Line; Cell Survival; Choline; Humans; Leukemia, Pr | 1992 |
Effects of antineoplastic phospholipids on parameters of cell differentiation in U937 cells.
Topics: Antigens, Surface; Antineoplastic Agents; Blotting, Northern; Cell Transformation, Neoplastic; DNA P | 1990 |
Platelet-activating factor (PAF) antagonist WEB 2086 does not modulate the cytotoxicity of PAF or antitumour alkyl lysophospholipids ET-18-O-methyl and SRI 62-834 in HL-60 promyelocytic leukaemia cells.
Topics: Antineoplastic Agents; Azepines; Calcium; Cell Survival; Dose-Response Relationship, Drug; Drug Inte | 1991 |
Effects of hexadecylphosphocholine on protein kinase C and TPA-induced differentiation of HL60 cells.
Topics: Cell Differentiation; Cell Line; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Phospholipid Ethe | 1991 |
O-alkyl-O-methylglycerophosphocholine, an antineoplastic lipid, undergoes spontaneous redistribution between biological membranes prepared from HL-60 cells.
Topics: Antineoplastic Agents; Cell Fractionation; Cell Membrane; Centrifugation, Density Gradient; Cytoplas | 1989 |
HL-60 cells become resistant towards antitumor ether-linked phospholipids following differentiation into a granulocytic form.
Topics: Antineoplastic Agents; Biological Transport; Cell Differentiation; Cell Line; Cell Survival; Choline | 1988 |