edelfosine has been researched along with Acute Disease in 4 studies
edelfosine: RN given refers to parent cpd
edelfosine : A racemate comprising equimolar amounts of (R)- and (S)-edelfosine.
1-octadecyl-2-methylglycero-3-phosphocholine : A glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Minimal residual disease was measured with flow cytometry using leukemia-associated phenotypes as established at diagnosis." | 2.71 | Purging of peripheral blood stem cell transplants in AML: a predictive model based on minimal residual disease burden. ( Feller, N; Jansen-van der Weide, MC; Ossenkoppele, GJ; Schuurhuis, GJ; van der Pol, MA; Westra, GA, 2005) |
| " All the mice given cells not treated with ALP succumbed to leukemia, whereas there was a dose-response increase in survival in those given ALP treated cells." | 1.28 | Purging leukemia remission marrows with alkyl-lysophospholipids, preclinical and clinical results. ( Berdel, WE; Glasser, L; Okamoto, S; Olson, AC; Vogler, WR, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feller, N | 1 |
| Jansen-van der Weide, MC | 1 |
| van der Pol, MA | 1 |
| Westra, GA | 1 |
| Ossenkoppele, GJ | 1 |
| Schuurhuis, GJ | 1 |
| Vogler, WR | 2 |
| Berdel, WE | 2 |
| Wierenga, PK | 1 |
| Setroikromo, R | 1 |
| Vellenga, E | 1 |
| Kampinga, HH | 1 |
| Olson, AC | 1 |
| Okamoto, S | 1 |
| Glasser, L | 1 |
2 trials available for edelfosine and Acute Disease
| Article | Year |
|---|---|
Purging of peripheral blood stem cell transplants in AML: a predictive model based on minimal residual disease burden.
Topics: Acute Disease; Adolescent; Adult; Bone Marrow Purging; Cryopreservation; Decision Making; Female; Fe | 2005 |
Autologous bone marrow transplantation with alkyl-lysophospholipid-purged marrow.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoc | 1993 |
2 other studies available for edelfosine and Acute Disease
| Article | Year |
|---|---|
Purging of acute myeloid leukaemia cells from stem cell grafts by hyperthermia: enhancement of the therapeutic index by the tetrapeptide AcSDKP and the alkyl-lysophospholipid ET-18-OCH(3).
Topics: Acute Disease; Animals; Bone Marrow Purging; Cell Cycle; Cell Death; Colony-Forming Units Assay; Hem | 2000 |
Purging leukemia remission marrows with alkyl-lysophospholipids, preclinical and clinical results.
Topics: Acute Disease; Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplan | 1990 |