Page last updated: 2024-08-23

edatrexate and Leukemia

edatrexate has been researched along with Leukemia in 2 studies

*Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) [MeSH]

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Christie, PH; DeGraw, JI; Gaumont, Y; Kisliuk, RL; Sirotnak, FM1
Belani, CP; Green, MR; Herndon, JE; Kindler, HL; Suzuki, Y; Vogelzang, NJ1

Trials

1 trial(s) available for edatrexate and Leukemia

ArticleYear
Edatrexate (10-ethyl-deaza-aminopterin) (NSC #626715) with or without leucovorin rescue for malignant mesothelioma. Sequential phase II trials by the cancer and leukemia group B.
    Cancer, 1999, Nov-15, Volume: 86, Issue:10

    Topics: Aminopterin; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Humans; Leucovorin; Leukemia; Male; Mesothelioma; Middle Aged; Pleural Neoplasms; Survival Rate; Treatment Failure

1999

Other Studies

1 other study(ies) available for edatrexate and Leukemia

ArticleYear
Synthesis and antifolate properties of 9-alkyl-10-deazaminopterins.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

    Topics: Aminopterin; Animals; Chemical Phenomena; Chemistry; Folic Acid Antagonists; Humans; Leukemia; Leukemia L1210; Methotrexate; Molecular Structure; Tumor Cells, Cultured

1990