edatrexate has been researched along with Leukemia L 1210 in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Christie, PH; DeGraw, JI; Gaumont, Y; Kisliuk, RL; Sirotnak, FM | 1 |
| Colwell, WT; DeGraw, JI; Piper, JR; Sirotnak, FM | 1 |
| Tsukagoshi, S | 1 |
| Johnson, CA; Otter, GM; Piper, JR; Sirotnak, FM | 1 |
| Otter, GM; Rumberger, BG; Schmid, FA; Sirotnak, FM | 1 |
| Fanucchi, MP; Farag, F; Kinahan, JJ; Samuels, LL; Sirotnak, FM; Vidal, PM; Young, CW | 1 |
| DeGraw, JI; Samuels, LL; Schmid, FA; Sirotnak, FM | 1 |
| Christie, PH; DeGraw, JI; Gaumont, Y; Kisliuk, RL; Schmid, FA; Sirotnak, FM; Tagawa, H | 1 |
| Moccio, DM; Samuels, LL; Sirotnak, FM | 1 |
1 review(s) available for edatrexate and Leukemia L 1210
| Article | Year |
|---|---|
[Development of antimetabolites, II].
Topics: Aminopterin; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cytarabine; Deoxycytidine; Humans; Leukemia L1210; Methotrexate; Mice; Trimetrexate | 1993 |
8 other study(ies) available for edatrexate and Leukemia L 1210
| Article | Year |
|---|---|
Synthesis and antifolate properties of 9-alkyl-10-deazaminopterins.
Topics: Aminopterin; Animals; Chemical Phenomena; Chemistry; Folic Acid Antagonists; Humans; Leukemia; Leukemia L1210; Methotrexate; Molecular Structure; Tumor Cells, Cultured | 1990 |
Synthesis and antitumor activity of 10-propargyl-10-deazaaminopterin.
Topics: Aminopterin; Animals; Antineoplastic Agents; Female; Leukemia L1210; Mammary Neoplasms, Experimental; Mice; Structure-Activity Relationship | 1993 |
Synthesis and antifolate evaluation of 10-ethyl-5-methyl-5,10- dideazaaminopterin and an alternative synthesis of 10-ethyl-10- deazaaminopterin (edatrexate).
Topics: Aminopterin; Animals; Antineoplastic Agents; Folic Acid Antagonists; Leukemia L1210; Tumor Cells, Cultured | 1992 |
Preferential selection during therapy in vivo by edatrexate compared to methotrexate of resistant L1210 cell variants with decreased folylpolyglutamate synthetase activity.
Topics: Aminopterin; Animals; Drug Resistance; Folic Acid Antagonists; Leukemia L1210; Methotrexate; Mice; Neoplasm Transplantation; Peptide Synthases; Phenotype | 1990 |
Fluorometric high-performance liquid chromatographic analysis of 10-deazaaminopterin, 10-ethyl-10-deazaaminopterin, and known metabolites.
Topics: Aminopterin; Animals; Chromatography, High Pressure Liquid; Humans; Leukemia L1210; Mice; Mice, Nude; Neoplasms; Polyglutamic Acid; Spectrometry, Fluorescence | 1985 |
10-Ethyl-10-deaza-aminopterin: structural design and biochemical, pharmacologic, and antitumor properties.
Topics: Aminopterin; Animals; Biological Transport; Biotransformation; Cell Division; Cell Membrane; Cell Survival; Folic Acid Antagonists; Intestine, Small; Leukemia L1210; Mice; Neoplasms, Experimental; Polyglutamic Acid; Structure-Activity Relationship | 1987 |
Synthesis and biological activity of resolved C-10 diastereomers of 10-methyl- and 10-ethyl-10-deazaminopterin.
Topics: Aminopterin; Animals; Folic Acid Antagonists; Leukemia L1210; Methotrexate; Mice; Stereoisomerism; Structure-Activity Relationship | 1986 |
Similar differential for total polyglutamylation and cytotoxicity among various folate analogues in human and murine tumor cells in vitro.
Topics: Aminopterin; Animals; Cells, Cultured; Folic Acid; Humans; Kinetics; Leukemia L1210; Methotrexate; Mice; Neoplasms; Pteroylpolyglutamic Acids; Tumor Stem Cell Assay | 1985 |