Compounds > edatrexate
Page last updated: 2024-08-23

edatrexate and Experimental Neoplasms

edatrexate has been researched along with Experimental Neoplasms in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DeGraw, JI; Goutas, LJ; Moccio, DM; Schmid, FA; Sirotnak, FM1
Otter, GM; Sirotnak, FM1
Otter, GM; Schmid, FA; Sirotnak, FM1
DeGraw, JI; Samuels, LL; Schmid, FA; Sirotnak, FM1

Other Studies

4 other study(ies) available for edatrexate and Experimental Neoplasms

ArticleYear
New folate analogs of the 10-deaza-aminopterin series. Further evidence for markedly increased antitumor efficacy compared with methotrexate in ascitic and solid murine tumor models.
    Cancer chemotherapy and pharmacology, 1984, Volume: 12, Issue:1

    Topics: Aminopterin; Animals; Drug Evaluation, Preclinical; Female; Methotrexate; Mice; Neoplasms, Experimental; Structure-Activity Relationship

1984
Effective combination therapy of metastatic murine solid tumors with edatrexate and the vinca alkaloids, vinblastine, navelbine and vindesine.
    Cancer chemotherapy and pharmacology, 1994, Volume: 33, Issue:4

    Topics: Aminopterin; Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Tumor Cells, Cultured; Vinblastine; Vindesine; Vinorelbine

1994
Markedly improved efficacy of edatrexate compared to methotrexate in a high-dose regimen with leucovorin rescue against metastatic murine solid tumors.
    Cancer research, 1993, Feb-01, Volume: 53, Issue:3

    Topics: Adenocarcinoma; Aminopterin; Animals; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fibrosarcoma; Leucovorin; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma, Experimental; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Salvage Therapy

1993
10-Ethyl-10-deaza-aminopterin: structural design and biochemical, pharmacologic, and antitumor properties.
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:5

    Topics: Aminopterin; Animals; Biological Transport; Biotransformation; Cell Division; Cell Membrane; Cell Survival; Folic Acid Antagonists; Intestine, Small; Leukemia L1210; Mice; Neoplasms, Experimental; Polyglutamic Acid; Structure-Activity Relationship

1987