edatrexate has been researched along with Colonic Neoplasms in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iijima, A; Kitoh, K; Kotake, Y; Koyanagi, N; Nomura, H; Ozawa, Y; Tamai, N; Yoshimatsu, K | 1 |
| Otter, GM; Schmid, FA; Sirotnak, FM | 1 |
| Israel, K; Kemeny, N; O'Hehir, M | 1 |
3 other study(ies) available for edatrexate and Colonic Neoplasms
| Article | Year |
|---|---|
Synthesis and antitumor activities of novel 6-5 fused ring heterocycle antifolates: N-[4-[omega-(2-amino-4-substituted-6,7-dihydrocyclopenta [d]pyrimidin-5-yl)alkyl]benzoyl]-L-glutamic acids.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Colonic Neoplasms; Folic Acid Antagonists; Glutamates; Humans; Leukemia P388; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Nude; Neoplasm Transplantation; Pyrimidines; Structure-Activity Relationship; Tumor Cells, Cultured | 1994 |
Markedly improved efficacy of edatrexate compared to methotrexate in a high-dose regimen with leucovorin rescue against metastatic murine solid tumors.
Topics: Adenocarcinoma; Aminopterin; Animals; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fibrosarcoma; Leucovorin; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma, Experimental; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Salvage Therapy | 1993 |
Phase II trial of 10-Edam in patients with advanced colorectal carcinoma.
Topics: Abdominal Pain; Adult; Aged; Aminopterin; Carcinoma; Colonic Neoplasms; Drug Evaluation; Female; Folic Acid Antagonists; Humans; Injections, Intravenous; Male; Middle Aged; Rectal Neoplasms; Remission Induction | 1990 |