edatrexate has been researched along with Carcinoma, Epidermoid in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iijima, A; Kitoh, K; Kotake, Y; Koyanagi, N; Nomura, H; Ozawa, Y; Tamai, N; Yoshimatsu, K | 1 |
| Braakhuis, BJ; Jansen, G; Kegel, A; Noordhuis, P; Peters, GJ | 1 |
| Armand, JP; Cappelaere, P; Clavel, M; Cognetti, F; de Graeff, A; de Mulder, PH; Schornagel, JH; Vermorken, JB; Verweij, J; Wildiers, J | 1 |
| Benner, SE; Dimery, IW; Esparaz, B; Frenning, D; Guillory-Perez, C; Hong, WK; Huber, MH; Lippman, SM; Shirinian, M | 1 |
| Benedetti, J; Ensley, J; Grunberg, SM; Kuebler, JP; Marshall, ME; Muirhead, MJ; Richert-Boe, KE; Schuller, DE | 1 |
| Braakhuis, BJ; Jansen, G; Peters, GJ | 1 |
| Broun, ER; Iseminger, KA; Lentz, SL; Lincoln, S; Malfetano, JH; Mannel, R; Rose, PG | 1 |
| Armand, JP; Cappelaere, P; Clavel, M; Cognetti, F; de Mulder, PH; Kirkpatrick, A; Schornagel, JH; Vermorken, JB; Verweij, J; Wildiers, J | 1 |
| Green, MD; Sherman, P; Zalcberg, J | 1 |
| Hordijk, GJ; Jansen, G; Kathmann, GA; Schornagel, JH; van der Laan, BF; Westerhof, GR | 1 |
| Braakhuis, BJ; Brown, DH; Snow, GB; Van Dongen, GA | 1 |
| Clavel, M; Cognetti, F; de Mulder, P; Henzen-Logmans, S; Schornagel, J; Vermorken, J; Verweij, J | 1 |
7 trial(s) available for edatrexate and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Randomized phase III trial of edatrexate versus methotrexate in patients with metastatic and/or recurrent squamous cell carcinoma of the head and neck: a European Organization for Research and Treatment of Cancer Head and Neck Cancer Cooperative Group stu
Topics: Agranulocytosis; Aminopterin; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Injections, Intravenous; Lung; Male; Methotrexate; Respiratory Distress Syndrome; Thrombocytopenia | 1995 |
Phase II study of carboplatin and edatrexate (10-EdAM) with leucovorin rescue for patients with recurrent squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Middle Aged; Neoplasm Recurrence, Local | 1994 |
Phase II study of edatrexate in advanced head and neck cancer. A Southwest Oncology Group study.
Topics: Adult; Aged; Aminopterin; Antineoplastic Agents; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local | 1994 |
A phase II trial of edatrexate in previously treated squamous cell cervical cancer: a Gynecologic Oncology Group study.
Topics: Adult; Aged; Aged, 80 and over; Aminopterin; Antineoplastic Agents; Carcinoma, Squamous Cell; Fanconi Syndrome; Female; Folic Acid Antagonists; Humans; Middle Aged; Neoplasm Recurrence, Local; Uterine Cervical Neoplasms | 1997 |
A phase II trial of 10-ethyl-10-deaza-aminopterin, a novel antifolate, in patients with advanced and/or recurrent squamous cell carcinoma of the head and neck. The EORTC Head and Neck Cancer Cooperative Group.
Topics: Adult; Aged; Aminopterin; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Female; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Leukopenia; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Thrombocytopenia | 1992 |
Phase II study of 10-EdAM in patients with squamous cell carcinoma of the head and neck, previously untreated with chemotherapy.
Topics: Adult; Aged; Aminopterin; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged | 1992 |
Toxic dermatitis induced by 10-ethyl-10-deaza-aminopterin (10-EdAM), a novel antifolate.
Topics: Aged; Aminopterin; Carcinoma, Squamous Cell; Dermatitis, Contact; Drug Evaluation; Female; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Male; Middle Aged; Skin | 1990 |
5 other study(ies) available for edatrexate and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Synthesis and antitumor activities of novel 6-5 fused ring heterocycle antifolates: N-[4-[omega-(2-amino-4-substituted-6,7-dihydrocyclopenta [d]pyrimidin-5-yl)alkyl]benzoyl]-L-glutamic acids.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Colonic Neoplasms; Folic Acid Antagonists; Glutamates; Humans; Leukemia P388; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Nude; Neoplasm Transplantation; Pyrimidines; Structure-Activity Relationship; Tumor Cells, Cultured | 1994 |
Importance of pharmacodynamics in the in vitro antiproliferative activity of the antifolates methotrexate and 10-ethyl-10-deazaaminopterin against human head and neck squamous cell carcinoma.
Topics: Aminopterin; Carcinoma, Squamous Cell; Cell Division; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Polyglutamic Acid; Tumor Cells, Cultured | 1993 |
Variable pharmacodynamics of antifolates in squamous cell carcinoma of the head and neck.
Topics: Aminopterin; Carcinoma, Squamous Cell; Cell Division; Cell Line; Drug Resistance; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Tumor Cells, Cultured | 1993 |
In vitro activity of novel antifolates against human squamous carcinoma cell lines of the head and neck with inherent resistance to methotrexate.
Topics: Aminopterin; Biological Transport; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cell Membrane; Drug Resistance; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Tumor Cells, Cultured | 1992 |
Comparative study of the sensitivity of head and neck cell lines to methotrexate (MTX) and the analog 10-ethyl, 10-deazaaminopterin (10-EdAM).
Topics: Aminopterin; Carcinoma, Squamous Cell; Cell Line; Folic Acid Antagonists; Head and Neck Neoplasms; In Vitro Techniques; Methotrexate; Tumor Cells, Cultured | 1990 |