edatrexate has been researched along with Benign Neoplasms in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 8 (72.73) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheson, BD; Phillips, PH; Sorenson, JM | 1 |
| Allegra, CJ; Takimoto, CH | 1 |
| Edelman, MJ; Gandara, DR; Lau, D; Lauder, I; Meyers, F; Perez, EA; Turrell, C; Uhrich, M | 1 |
| Bertino, JR; Densmore, CL; Fleisher, M; Grant, SC; Heelan, RT; Kris, MG; Krol, G; Miller, VA; Pfister, DG; Pisters, KM; Rigas, JR; Sirotnak, FM; Tong, W; Tyson, LB | 1 |
| Sirotnak, FM | 1 |
| Aghi, M; Breakefield, XO; Kramm, CM | 1 |
| Chou, TC; Fennelly, DW; Grant, SC; Heelan, RT; Kris, MG; Miller, VA; Pisters, KM; Rigas, JR; Sirotnak, FM | 1 |
| Fleming, GF; Schilsky, RL | 1 |
| Fanucchi, MP; Farag, F; Kinahan, JJ; Samuels, LL; Sirotnak, FM; Vidal, PM; Young, CW | 1 |
| Fanucchi, MP; Farag, F; Gralla, RJ; Kinahan, JJ; Kris, MG; Marks, LD; O'Connell, JP; Wertheim, MS; Williams, L; Young, CW | 1 |
| Moccio, DM; Samuels, LL; Sirotnak, FM | 1 |
2 review(s) available for edatrexate and Benign Neoplasms
| Article | Year |
|---|---|
New antifolates in clinical development.
Topics: Aminopterin; Antimetabolites, Antineoplastic; Antineoplastic Agents; Drugs, Investigational; Folic Acid Antagonists; Humans; Neoplasms; Pyrimidines; Quinazolines; Thiophenes; Trimetrexate | 1995 |
Antifolates: the next generation.
Topics: Aminopterin; Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Clinical Trials as Topic; Drug Evaluation; Folic Acid Antagonists; Forecasting; Humans; Neoplasms; Pyrimidines; Quinazolines; Tetrahydrofolates; Thiophenes; Trimetrexate | 1992 |
4 trial(s) available for edatrexate and Benign Neoplasms
| Article | Year |
|---|---|
Phase I trial of edatrexate plus carboplatin in advanced solid tumors: amelioration of dose-limiting mucositis by ice chip cryotherapy.
Topics: Adult; Aged; Aminopterin; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cryotherapy; Exanthema; Female; Humans; Leukopenia; Male; Middle Aged; Mucous Membrane; Neoplasms; Vomiting | 1998 |
High-dose edatrexate with oral leucovorin rescue: a phase I and clinical pharmacological study in adults with advanced cancer.
Topics: Administration, Oral; Adult; Aged; Aminopterin; Antineoplastic Agents; Drug Interactions; Drug Monitoring; Female; Humans; Leucovorin; Male; Middle Aged; Neoplasms | 1996 |
Phase I study of the sequential administration of edatrexate and paclitaxel in patients with advanced solid tumors.
Topics: Adult; Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Male; Middle Aged; Neoplasms; Paclitaxel | 1999 |
Phase I trial and clinical pharmacological evaluation of 10-ethyl-10-deazaaminopterin in adult patients with advanced cancer.
Topics: Adult; Aminopterin; Antimetabolites, Antineoplastic; Drug Evaluation; Half-Life; Humans; Neoplasms; Skin Neoplasms | 1988 |
5 other study(ies) available for edatrexate and Benign Neoplasms
| Article | Year |
|---|---|
Clinical trials referral resource. Clinical trials using edatrexate.
Topics: Aminopterin; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Female; Humans; Male; Neoplasms | 1993 |
Enhancing cytotoxic sensitivity of tumor cells to antifolates: another opportunity for gene therapy?
Topics: Aminopterin; Animals; Antineoplastic Agents; Clone Cells; Folic Acid Antagonists; Genetic Therapy; Humans; Neoplasms; Peptide Synthases; Polyglutamic Acid; Tumor Cells, Cultured | 1999 |
Folylpolyglutamyl synthetase gene transfer and glioma antifolate sensitivity in culture and in vivo.
Topics: Aminopterin; Animals; Antimetabolites, Antineoplastic; Chromatography, Thin Layer; Dogs; Dose-Response Relationship, Drug; Folic Acid Antagonists; Gene Transfer Techniques; Genetic Therapy; Glioma; Humans; Methotrexate; Neoplasms; Peptide Synthases; Rats; Transduction, Genetic; Transfection; Tumor Cells, Cultured | 1999 |
Fluorometric high-performance liquid chromatographic analysis of 10-deazaaminopterin, 10-ethyl-10-deazaaminopterin, and known metabolites.
Topics: Aminopterin; Animals; Chromatography, High Pressure Liquid; Humans; Leukemia L1210; Mice; Mice, Nude; Neoplasms; Polyglutamic Acid; Spectrometry, Fluorescence | 1985 |
Similar differential for total polyglutamylation and cytotoxicity among various folate analogues in human and murine tumor cells in vitro.
Topics: Aminopterin; Animals; Cells, Cultured; Folic Acid; Humans; Kinetics; Leukemia L1210; Methotrexate; Mice; Neoplasms; Pteroylpolyglutamic Acids; Tumor Stem Cell Assay | 1985 |