edaravone has been researched along with Subarachnoid Hemorrhage in 6 studies
Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
Excerpt | Relevance | Reference |
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"It is hypothesized that cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) is induced by free radicals released from a subarachnoid clot." | 6.74 | Effect of a free radical scavenger, edaravone, in the treatment of patients with aneurysmal subarachnoid hemorrhage. ( Asano, K; Munakata, A; Nakano, T; Naraoka, M; Ohkuma, H; Shimamura, N, 2009) |
"The degree of cerebral vasospasm was evaluated by measuring the diameter of each basilar artery, and the expression of Rho-kinase in the vascular wall was examined by western blotting." | 5.37 | Effect of a free radical scavenger, edaravone, on free radical reactions: related signal transduction and cerebral vasospasm in the rabbit subarachnoid hemorrhage model. ( Munakata, A; Ohkuma, H; Shimamura, N, 2011) |
"It is hypothesized that cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) is induced by free radicals released from a subarachnoid clot." | 2.74 | Effect of a free radical scavenger, edaravone, in the treatment of patients with aneurysmal subarachnoid hemorrhage. ( Asano, K; Munakata, A; Nakano, T; Naraoka, M; Ohkuma, H; Shimamura, N, 2009) |
"Cerebral vasospasm is a major cause of cerebral ischemia and poor outcomes in the setting of aneurysmal subarachnoid hemorrhage (SAH)." | 2.44 | Novel treatments for cerebral vasospasm following aneurysmal subarachnoid hemorrhage. ( Lehmann, E; Sagher, O, 2008) |
"Edaravone treatment significantly ameliorated neurological deficits, brain edema, and BBB disruption." | 1.51 | The Role of Oxidative Stress in Microvascular Disturbances after Experimental Subarachnoid Hemorrhage. ( Fumoto, T; Katagai, T; Li, Y; Naraoka, M; Ohkuma, H; Shimamura, N, 2019) |
"The degree of cerebral vasospasm was evaluated by measuring the diameter of each basilar artery, and the expression of Rho-kinase in the vascular wall was examined by western blotting." | 1.37 | Effect of a free radical scavenger, edaravone, on free radical reactions: related signal transduction and cerebral vasospasm in the rabbit subarachnoid hemorrhage model. ( Munakata, A; Ohkuma, H; Shimamura, N, 2011) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (50.00) | 29.6817 |
2010's | 3 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Nagashima, H | 1 |
Miwa, T | 1 |
Horiguchi, T | 1 |
Tomio, R | 1 |
Nakagawa, Y | 1 |
Yoshida, K | 1 |
Fumoto, T | 1 |
Naraoka, M | 2 |
Katagai, T | 1 |
Li, Y | 1 |
Shimamura, N | 3 |
Ohkuma, H | 3 |
Lehmann, E | 1 |
Sagher, O | 1 |
Munakata, A | 2 |
Nakano, T | 1 |
Asano, K | 1 |
Gao, Y | 1 |
Ding, XS | 1 |
Xu, S | 1 |
Wang, W | 1 |
Zuo, QL | 1 |
Kuai, F | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Efficacy and Safety of Nerve Growth Factor or Edaravone on Alcohol-induced Brain Injury[NCT03968042] | Phase 2 | 150 participants (Anticipated) | Interventional | 2019-06-30 | Recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 review available for edaravone and Subarachnoid Hemorrhage
Article | Year |
---|---|
Novel treatments for cerebral vasospasm following aneurysmal subarachnoid hemorrhage.
Topics: Animals; Anti-Inflammatory Agents; Antipyrine; Edaravone; Fibrinolytic Agents; Free Radical Scavenge | 2008 |
1 trial available for edaravone and Subarachnoid Hemorrhage
Article | Year |
---|---|
Effect of a free radical scavenger, edaravone, in the treatment of patients with aneurysmal subarachnoid hemorrhage.
Topics: Antipyrine; Cerebral Infarction; Comorbidity; Edaravone; Female; Free Radical Scavengers; Humans; Ja | 2009 |
4 other studies available for edaravone and Subarachnoid Hemorrhage
Article | Year |
---|---|
Hyperperfusion after Clipping of Aneurysm: A Rare Entity.
Topics: Aged; Aneurysm, Ruptured; Angiography, Digital Subtraction; Antipyrine; Cerebral Angiography; Cerebr | 2018 |
The Role of Oxidative Stress in Microvascular Disturbances after Experimental Subarachnoid Hemorrhage.
Topics: Animals; Antioxidants; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries; Disease Models, Anim | 2019 |
Neuroprotective effects of edaravone on early brain injury in rats after subarachnoid hemorrhage.
Topics: Animals; Antipyrine; Blotting, Western; Brain Injuries; Edaravone; Immunohistochemistry; Male; Malon | 2009 |
Effect of a free radical scavenger, edaravone, on free radical reactions: related signal transduction and cerebral vasospasm in the rabbit subarachnoid hemorrhage model.
Topics: Animals; Antipyrine; Basilar Artery; Disease Models, Animal; Edaravone; Free Radical Scavengers; Gen | 2011 |