Page last updated: 2024-10-30

edaravone and Subarachnoid Hemorrhage

edaravone has been researched along with Subarachnoid Hemorrhage in 6 studies

Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.

Research Excerpts

ExcerptRelevanceReference
"It is hypothesized that cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) is induced by free radicals released from a subarachnoid clot."6.74Effect of a free radical scavenger, edaravone, in the treatment of patients with aneurysmal subarachnoid hemorrhage. ( Asano, K; Munakata, A; Nakano, T; Naraoka, M; Ohkuma, H; Shimamura, N, 2009)
"The degree of cerebral vasospasm was evaluated by measuring the diameter of each basilar artery, and the expression of Rho-kinase in the vascular wall was examined by western blotting."5.37Effect of a free radical scavenger, edaravone, on free radical reactions: related signal transduction and cerebral vasospasm in the rabbit subarachnoid hemorrhage model. ( Munakata, A; Ohkuma, H; Shimamura, N, 2011)
"It is hypothesized that cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) is induced by free radicals released from a subarachnoid clot."2.74Effect of a free radical scavenger, edaravone, in the treatment of patients with aneurysmal subarachnoid hemorrhage. ( Asano, K; Munakata, A; Nakano, T; Naraoka, M; Ohkuma, H; Shimamura, N, 2009)
"Cerebral vasospasm is a major cause of cerebral ischemia and poor outcomes in the setting of aneurysmal subarachnoid hemorrhage (SAH)."2.44Novel treatments for cerebral vasospasm following aneurysmal subarachnoid hemorrhage. ( Lehmann, E; Sagher, O, 2008)
"Edaravone treatment significantly ameliorated neurological deficits, brain edema, and BBB disruption."1.51The Role of Oxidative Stress in Microvascular Disturbances after Experimental Subarachnoid Hemorrhage. ( Fumoto, T; Katagai, T; Li, Y; Naraoka, M; Ohkuma, H; Shimamura, N, 2019)
"The degree of cerebral vasospasm was evaluated by measuring the diameter of each basilar artery, and the expression of Rho-kinase in the vascular wall was examined by western blotting."1.37Effect of a free radical scavenger, edaravone, on free radical reactions: related signal transduction and cerebral vasospasm in the rabbit subarachnoid hemorrhage model. ( Munakata, A; Ohkuma, H; Shimamura, N, 2011)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nagashima, H1
Miwa, T1
Horiguchi, T1
Tomio, R1
Nakagawa, Y1
Yoshida, K1
Fumoto, T1
Naraoka, M2
Katagai, T1
Li, Y1
Shimamura, N3
Ohkuma, H3
Lehmann, E1
Sagher, O1
Munakata, A2
Nakano, T1
Asano, K1
Gao, Y1
Ding, XS1
Xu, S1
Wang, W1
Zuo, QL1
Kuai, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of Nerve Growth Factor or Edaravone on Alcohol-induced Brain Injury[NCT03968042]Phase 2150 participants (Anticipated)Interventional2019-06-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for edaravone and Subarachnoid Hemorrhage

ArticleYear
Novel treatments for cerebral vasospasm following aneurysmal subarachnoid hemorrhage.
    Acta neurochirurgica. Supplement, 2008, Volume: 105

    Topics: Animals; Anti-Inflammatory Agents; Antipyrine; Edaravone; Fibrinolytic Agents; Free Radical Scavenge

2008

Trials

1 trial available for edaravone and Subarachnoid Hemorrhage

ArticleYear
Effect of a free radical scavenger, edaravone, in the treatment of patients with aneurysmal subarachnoid hemorrhage.
    Neurosurgery, 2009, Volume: 64, Issue:3

    Topics: Antipyrine; Cerebral Infarction; Comorbidity; Edaravone; Female; Free Radical Scavengers; Humans; Ja

2009

Other Studies

4 other studies available for edaravone and Subarachnoid Hemorrhage

ArticleYear
Hyperperfusion after Clipping of Aneurysm: A Rare Entity.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2018, Volume: 27, Issue:5

    Topics: Aged; Aneurysm, Ruptured; Angiography, Digital Subtraction; Antipyrine; Cerebral Angiography; Cerebr

2018
The Role of Oxidative Stress in Microvascular Disturbances after Experimental Subarachnoid Hemorrhage.
    Translational stroke research, 2019, Volume: 10, Issue:6

    Topics: Animals; Antioxidants; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries; Disease Models, Anim

2019
Neuroprotective effects of edaravone on early brain injury in rats after subarachnoid hemorrhage.
    Chinese medical journal, 2009, Aug-20, Volume: 122, Issue:16

    Topics: Animals; Antipyrine; Blotting, Western; Brain Injuries; Edaravone; Immunohistochemistry; Male; Malon

2009
Effect of a free radical scavenger, edaravone, on free radical reactions: related signal transduction and cerebral vasospasm in the rabbit subarachnoid hemorrhage model.
    Acta neurochirurgica. Supplement, 2011, Volume: 110, Issue:Pt 2

    Topics: Animals; Antipyrine; Basilar Artery; Disease Models, Animal; Edaravone; Free Radical Scavengers; Gen

2011