Page last updated: 2024-10-30

edaravone and Pre-Eclampsia

edaravone has been researched along with Pre-Eclampsia in 2 studies

Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.

Research Excerpts

ExcerptRelevanceReference
" Edaravone is a powerful free radical scavenger used for the treatment of ischemia/reperfusion diseases due to its anti-oxidative stress and anti-inflammatory properties."8.02Effect of edaravone on pregnant mice and their developing fetuses subjected to placental ischemia. ( Abe, K; Atallah, M; Yamashita, T, 2021)
"Pretreatment with edaravone significantly inhibited hypoxia-induced oxidative stress formation and sFlt-1 expression in trophoblasts."5.40Edaravone inhibits hypoxia-induced trophoblast-soluble Fms-like tyrosine kinase 1 expression: a possible therapeutic approach to preeclampsia. ( Han, L; Liu, XX; Luo, QQ; Yan, T; Zhao, Y; Zheng, YF; Zou, L, 2014)
" Edaravone is a powerful free radical scavenger used for the treatment of ischemia/reperfusion diseases due to its anti-oxidative stress and anti-inflammatory properties."4.02Effect of edaravone on pregnant mice and their developing fetuses subjected to placental ischemia. ( Abe, K; Atallah, M; Yamashita, T, 2021)
"Pretreatment with edaravone significantly inhibited hypoxia-induced oxidative stress formation and sFlt-1 expression in trophoblasts."1.40Edaravone inhibits hypoxia-induced trophoblast-soluble Fms-like tyrosine kinase 1 expression: a possible therapeutic approach to preeclampsia. ( Han, L; Liu, XX; Luo, QQ; Yan, T; Zhao, Y; Zheng, YF; Zou, L, 2014)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Atallah, M1
Yamashita, T1
Abe, K1
Zhao, Y1
Zheng, YF1
Luo, QQ1
Yan, T1
Liu, XX1
Han, L1
Zou, L1

Other Studies

2 other studies available for edaravone and Pre-Eclampsia

ArticleYear
Effect of edaravone on pregnant mice and their developing fetuses subjected to placental ischemia.
    Reproductive biology and endocrinology : RB&E, 2021, Feb-06, Volume: 19, Issue:1

    Topics: Animals; Disease Models, Animal; Edaravone; Female; Ischemia; Male; Mice; Mice, Inbred C57BL; Oxidat

2021
Edaravone inhibits hypoxia-induced trophoblast-soluble Fms-like tyrosine kinase 1 expression: a possible therapeutic approach to preeclampsia.
    Placenta, 2014, Volume: 35, Issue:7

    Topics: Antipyrine; Cell Hypoxia; Cell Line; Cobalt; Edaravone; Female; Free Radical Scavengers; Gene Expres

2014